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Translocation (X;10)(p10;p10): A rare but nonrandom chromosomal abnormality in acute leukemia of myeloid differentiation

  • K. F. Wong
  • , K. J. Hayes
  • , Y. O. Huh
  • , M. Albitar
  • , A. B. Glassman

Research output: Contribution to journal › Article › peer-review

Abstract

Structural abnormality of chromosome X is uncommonly seen in patients with acute leukemia, and translocation between chromosome X and 10 is an exceedingly rare event. In this report, we describe the occurrence of t(X;10)(p10;p10) in two patients with acute leukemia, one with acute monocytic leukemia and the other with myeloblastic relapse arising from bilineage leukemia. To our knowledge, similar chromosomal abnormality has been reported only twice in the literature.

Original languageEnglish (US)
Pages (from-to)153-155
Number of pages3
JournalCancer Genetics and Cytogenetics
Volume86
Issue number2
DOIs
StatePublished - Feb 1996

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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