Treatment of malignant paravertebral and mesenchymal tumor pain with cryoablation

Yong Li, Zhi Guo, Wenge Xing, Haitao Wang, Xueling Yang, Changfu Liu

    Research output: Contribution to journalArticle


    Objective: This study aimed to analyze the feasibility, safety, and efficacy of cryoablation in treating pain caused by malignant paravertebral and mesenchymal tumor.

    Methods: Cryoablation was performed in 31 patients with unresectable and painful malignant paravertebral and mesenchymal tumors whose pain was poorly controlled by conventional treatment methods. Tumors ranged in size from 3 cm to 20 cm. Pain experienced by the patient was assessed using the Brief Pain Inventory (BPI) at 0, 1 day, 1 week, 1 month, and 3 months post-cryoablation.

    Results: BPI scores were divided into two categories, i.e., the influence and the severity of pain. Both categories showed downward trend after cryoablation. Pain severity score significantly decreased (P=0.001, t= 3.862; P=0.031, t=2.261) 1 day and 1 month after cryoablation. Pain influence score also significantly decreased (P=0.016, t=2.566; P= 0.036, t=2.195) 1 day and 1 week after cryoablation. Two patients (6.45%) had mild complications, and no serious complication was observed.

    Conclusion: Cryoablation is a low-risk and well-tolerated topical treatment for pain caused by unresectable malignant paravertebral and mesenchymal tumors.

    Original languageEnglish (US)
    Pages (from-to)1052-1056
    Number of pages5
    JournalChinese Journal of Clinical Oncology
    Issue number16
    StatePublished - Aug 30 2014


    • Cryoablation
    • Mesenchymal tumor
    • Pain
    • Paravertebral

    ASJC Scopus subject areas

    • Oncology
    • Cancer Research

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