Tumor evolution in response to chemotherapy: Phenotype versus genotype

Research output: Contribution to journalShort surveypeer-review

44 Scopus citations

Abstract

In this issue of Cell Reports, Almendro etal. report one of the first comprehensive studies on the intratumor heterogeneity of cell phenotypes and genotypes before and after chemotherapy in breast cancer. These data challenge the concept of genetic population bottlenecks and suggest that cellular phenotypes play an important role in developing resistance to therapy.

Original languageEnglish (US)
Pages (from-to)417-419
Number of pages3
JournalCell Reports
Volume6
Issue number3
DOIs
StatePublished - Feb 13 2014

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

Fingerprint

Dive into the research topics of 'Tumor evolution in response to chemotherapy: Phenotype versus genotype'. Together they form a unique fingerprint.

Cite this