Tumor localization in tissue microarrays using rotation invariant superpixel pyramids

Shazia Akbar, Lee Jordan, Alastair M. Thompson, Stephen J. McKenna

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Scopus citations

Abstract

Tumor localization is an important component of histopathology image analysis; it has yet to be reliably automated for breast cancer histopathology. This paper investigates the use of superpixel classification to localize tumor regions. A superpixel representation retains information about visual structures such as cellular compartments, connective tissue, lumen and fatty tissue without having to commit to semantic segmentation at this level. In order to localize tumor in large images, a rotation invariant spatial pyramid representation is proposed using bags-of-superpixels. The method is evaluated on expert-annotated oestrogen-receptor stained TMA spots and compared to other superpixel classification techniques. Results demonstrate that it performs favorably.

Original languageEnglish (US)
Title of host publication2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015
PublisherIEEE Computer Society
Pages1292-1295
Number of pages4
ISBN (Electronic)9781479923748
DOIs
StatePublished - Jul 21 2015
Event12th IEEE International Symposium on Biomedical Imaging, ISBI 2015 - Brooklyn, United States
Duration: Apr 16 2015Apr 19 2015

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2015-July
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other12th IEEE International Symposium on Biomedical Imaging, ISBI 2015
Country/TerritoryUnited States
CityBrooklyn
Period4/16/154/19/15

Keywords

  • rotation invariant spatial pyramid
  • spatial bag-of-words
  • superpixels
  • tumor classification

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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