@inbook{37bc6564abec48d0b3ec59baaec84a7c,
title = "Understanding the Genomic Ultraconservations: T-UCRs and Cancer",
abstract = "Transcribed ultraconserved regions (T-UCRs) are genomic regions conserved across large evolutionary distances, which encode for noncoding RNAs that serve as regulators of gene expression. Although T-UCRs have been linked to multiple aspects of mammalian gene regulation, the roles of their extreme evolutionary conservation remain largely unexplained. Growing body of literature is now focusing on T-UCRs as potential cancer biomarkers or as new drug targets. Here we present an overview of the discoveries so far published about the role of T-UCR in cancer and disease.",
keywords = "Cancer, Noncoding RNA, T-UCR, Transcribed ultraconserved region",
author = "Linda Fabris and Calin, {George A.}",
note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",
year = "2017",
doi = "10.1016/bs.ircmb.2017.04.004",
language = "English (US)",
series = "International Review of Cell and Molecular Biology",
publisher = "Elsevier Inc.",
pages = "159--172",
booktitle = "International Review of Cell and Molecular Biology",
}