@inbook{8cf5a58d10454e73b1392434286940d6,
title = "Using aptamers to study protein-protein interactions",
abstract = "The emerging science of systems biology focuses on the systematic study of complex interactions in whole biological systems. A systemic, or integrative, methodology is employed as the chief means of discovering new properties and understanding the aggregate of processes that occur in a biological system. Accordingly, the Human Genome Project has provided a complete map of genes and resultant proteins corresponding to their function. Protein-protein interactions are important pieces of this biological tapestry, and understanding how they work cooperatively in a cell will result in a better understanding of the whole organism. To accomplish this objective, we report the use of DNA/RNA aptamers as a novel tool for the study and elucidation of protein-protein interactions, both in vivo and in vitro.",
keywords = "Aptamers, FRET, Fluorescence anisotropy, Protein-protein interactions",
author = "Parag Parekh and Jennifer Martin and Yan Chen and Dalia Colon and Hui Wang and Weihong Tan",
note = "Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",
year = "2008",
doi = "10.1007/10_2008_104",
language = "English (US)",
isbn = "9783540688174",
series = "Advances in Biochemical Engineering/Biotechnology",
pages = "177--194",
editor = "Meike Werther and Harald Seitz",
booktitle = "Protein - Protein Interaction",
}