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Using Both Efficacy and Toxicity for Dose-Finding

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationStatistical Methods for Dose-Finding Experiments
Publisherwiley
Pages275-285
Number of pages11
ISBN (Electronic)9780470861257
ISBN (Print)0470861231, 9780470861233
DOIs
StatePublished - Jun 20 2006

Keywords

  • Bivariate binary regression models
  • Computer simulation study
  • Dose-finding algorithm
  • Dose-outcome models
  • Efficacy and toxicity in dose-finding
  • Outcome-adaptive Bayesian method using efficacy (E) and toxicity (T )
  • Software package - EffTox
  • Trade-off contours
  • Two dose-outcome curves and computer simulation

ASJC Scopus subject areas

  • General Medicine

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