Varying kVp as a means of reducing CT breast dose to pediatric patients

K. B. Mathieu, A. C. Turner, M. Khatonabadi, M. F. McNitt-Gray, C. H. Cagnon, D. D. Cody

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We investigated the possibility of reducing radiation dose to the breast tissue of pediatric females by using multiple tube voltages within a single CT examination. The peak kilovoltage (kVp) was adjusted when the x-ray beam was directly exposing the representative breast tissue of a 5-year-old, 10-year-old, and an adult female anthropomorphic phantom; this strategy was called kVp splitting and was emulated by using a different kVp over the anterior and posterior tube angles. Dose savings from kVp splitting were calculated relative to using a fixed kVp over all tube angles and the results indicated savings in all three phantoms when using 80 kVp over the posterior tube angles regardless of the anterior kVp. Monte Carlo (MC) simulations with and without kVp splitting were performed to estimate absorbed breast dose in voxelized models constructed from the CT images of pediatric female patients; 80 kVp was used over the posterior tube angles. The MC simulations revealed breast dose savings of between 9.8% and 33% from using kVp splitting compared to simulations using a fixed kVp protocol with the anterior technique. Before this strategy could be implemented clinically, the development of suitable image reconstruction algorithms and the image quality of scans with kVp splitting would need further study.

Original languageEnglish (US)
Pages (from-to)4455-4469
Number of pages15
JournalPhysics in medicine and biology
Volume58
Issue number13
DOIs
StatePublished - Jul 7 2013

Fingerprint

Breast
Pediatrics
Computer-Assisted Image Processing
X-Rays
Radiation

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Varying kVp as a means of reducing CT breast dose to pediatric patients. / Mathieu, K. B.; Turner, A. C.; Khatonabadi, M.; McNitt-Gray, M. F.; Cagnon, C. H.; Cody, D. D.

In: Physics in medicine and biology, Vol. 58, No. 13, 07.07.2013, p. 4455-4469.

Research output: Contribution to journalArticle

Mathieu, K. B. ; Turner, A. C. ; Khatonabadi, M. ; McNitt-Gray, M. F. ; Cagnon, C. H. ; Cody, D. D. / Varying kVp as a means of reducing CT breast dose to pediatric patients. In: Physics in medicine and biology. 2013 ; Vol. 58, No. 13. pp. 4455-4469.
@article{58560053968b41a4beda5fa8292e7252,
title = "Varying kVp as a means of reducing CT breast dose to pediatric patients",
abstract = "We investigated the possibility of reducing radiation dose to the breast tissue of pediatric females by using multiple tube voltages within a single CT examination. The peak kilovoltage (kVp) was adjusted when the x-ray beam was directly exposing the representative breast tissue of a 5-year-old, 10-year-old, and an adult female anthropomorphic phantom; this strategy was called kVp splitting and was emulated by using a different kVp over the anterior and posterior tube angles. Dose savings from kVp splitting were calculated relative to using a fixed kVp over all tube angles and the results indicated savings in all three phantoms when using 80 kVp over the posterior tube angles regardless of the anterior kVp. Monte Carlo (MC) simulations with and without kVp splitting were performed to estimate absorbed breast dose in voxelized models constructed from the CT images of pediatric female patients; 80 kVp was used over the posterior tube angles. The MC simulations revealed breast dose savings of between 9.8{\%} and 33{\%} from using kVp splitting compared to simulations using a fixed kVp protocol with the anterior technique. Before this strategy could be implemented clinically, the development of suitable image reconstruction algorithms and the image quality of scans with kVp splitting would need further study.",
author = "Mathieu, {K. B.} and Turner, {A. C.} and M. Khatonabadi and McNitt-Gray, {M. F.} and Cagnon, {C. H.} and Cody, {D. D.}",
year = "2013",
month = "7",
day = "7",
doi = "10.1088/0031-9155/58/13/4455",
language = "English (US)",
volume = "58",
pages = "4455--4469",
journal = "Physics in Medicine and Biology",
issn = "0031-9155",
publisher = "IOP Publishing Ltd.",
number = "13",

}

TY - JOUR

T1 - Varying kVp as a means of reducing CT breast dose to pediatric patients

AU - Mathieu, K. B.

AU - Turner, A. C.

AU - Khatonabadi, M.

AU - McNitt-Gray, M. F.

AU - Cagnon, C. H.

AU - Cody, D. D.

PY - 2013/7/7

Y1 - 2013/7/7

N2 - We investigated the possibility of reducing radiation dose to the breast tissue of pediatric females by using multiple tube voltages within a single CT examination. The peak kilovoltage (kVp) was adjusted when the x-ray beam was directly exposing the representative breast tissue of a 5-year-old, 10-year-old, and an adult female anthropomorphic phantom; this strategy was called kVp splitting and was emulated by using a different kVp over the anterior and posterior tube angles. Dose savings from kVp splitting were calculated relative to using a fixed kVp over all tube angles and the results indicated savings in all three phantoms when using 80 kVp over the posterior tube angles regardless of the anterior kVp. Monte Carlo (MC) simulations with and without kVp splitting were performed to estimate absorbed breast dose in voxelized models constructed from the CT images of pediatric female patients; 80 kVp was used over the posterior tube angles. The MC simulations revealed breast dose savings of between 9.8% and 33% from using kVp splitting compared to simulations using a fixed kVp protocol with the anterior technique. Before this strategy could be implemented clinically, the development of suitable image reconstruction algorithms and the image quality of scans with kVp splitting would need further study.

AB - We investigated the possibility of reducing radiation dose to the breast tissue of pediatric females by using multiple tube voltages within a single CT examination. The peak kilovoltage (kVp) was adjusted when the x-ray beam was directly exposing the representative breast tissue of a 5-year-old, 10-year-old, and an adult female anthropomorphic phantom; this strategy was called kVp splitting and was emulated by using a different kVp over the anterior and posterior tube angles. Dose savings from kVp splitting were calculated relative to using a fixed kVp over all tube angles and the results indicated savings in all three phantoms when using 80 kVp over the posterior tube angles regardless of the anterior kVp. Monte Carlo (MC) simulations with and without kVp splitting were performed to estimate absorbed breast dose in voxelized models constructed from the CT images of pediatric female patients; 80 kVp was used over the posterior tube angles. The MC simulations revealed breast dose savings of between 9.8% and 33% from using kVp splitting compared to simulations using a fixed kVp protocol with the anterior technique. Before this strategy could be implemented clinically, the development of suitable image reconstruction algorithms and the image quality of scans with kVp splitting would need further study.

UR - http://www.scopus.com/inward/record.url?scp=84879482928&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879482928&partnerID=8YFLogxK

U2 - 10.1088/0031-9155/58/13/4455

DO - 10.1088/0031-9155/58/13/4455

M3 - Article

C2 - 23756499

AN - SCOPUS:84879482928

VL - 58

SP - 4455

EP - 4469

JO - Physics in Medicine and Biology

JF - Physics in Medicine and Biology

SN - 0031-9155

IS - 13

ER -