TY - GEN
T1 - White light oblique-incidence diffuse reflectance spectroscopy for classification of in vivo pigmented skin lesions
AU - Garcia-Uribe, Alejandro
AU - Smith, Elizabeth B.
AU - Duvic, Madeleine
AU - Wang, Lihong V.
PY - 2007
Y1 - 2007
N2 - A study of in-vivo classification of pigmented skin lesions using oblique-incidence diffuse reflectance spectroscopy is presented. Spatio-spectral data in the wavelength range from 455 to 765 nm are collected from 111 pigmented lesions including 10 histopathologically diagnosed as melanoma. The first 67 lesions are used for training the classifiers, and 44 lesions are used for testing. The first classifier separates (1) malignant melanoma and severe dysplastic nevi from (2) moderate and mild dysplastic nevi, common nevi, actinic and seborrheic keratoses. The second classifier next distinguishes between (a) moderate and mild dysplastic nevi, common nevi from (b) actinic and seborrheic keratoses. The third classifier further separates (I) moderate and mild dysplastic nevi from (II) common nevi. The first classifier performs with 100% sensitivity and 91% specificity with overall classification rates of 93% and 95 % for the training and testing sets, respectively. The second classifier has classification rates of 95% and 97 % for the training and testing sets, respectively, whereas the third classifier has classification rates of 98% and 94 % for the training and testing sets, respectively.
AB - A study of in-vivo classification of pigmented skin lesions using oblique-incidence diffuse reflectance spectroscopy is presented. Spatio-spectral data in the wavelength range from 455 to 765 nm are collected from 111 pigmented lesions including 10 histopathologically diagnosed as melanoma. The first 67 lesions are used for training the classifiers, and 44 lesions are used for testing. The first classifier separates (1) malignant melanoma and severe dysplastic nevi from (2) moderate and mild dysplastic nevi, common nevi, actinic and seborrheic keratoses. The second classifier next distinguishes between (a) moderate and mild dysplastic nevi, common nevi from (b) actinic and seborrheic keratoses. The third classifier further separates (I) moderate and mild dysplastic nevi from (II) common nevi. The first classifier performs with 100% sensitivity and 91% specificity with overall classification rates of 93% and 95 % for the training and testing sets, respectively. The second classifier has classification rates of 95% and 97 % for the training and testing sets, respectively, whereas the third classifier has classification rates of 98% and 94 % for the training and testing sets, respectively.
KW - Lesion classification
KW - Oblique incidence reflectometry
KW - Skin cancer
KW - Spectroscopy
UR - http://www.scopus.com/inward/record.url?scp=34247360877&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34247360877&partnerID=8YFLogxK
U2 - 10.1117/12.699633
DO - 10.1117/12.699633
M3 - Conference contribution
AN - SCOPUS:34247360877
SN - 0819465488
SN - 9780819465481
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Interactions with Tissue and Cells XVIII
T2 - Optical Interactions with Tissue and Cells XVIII
Y2 - 22 January 2007 through 24 January 2007
ER -