Why Proteasome Inhibitors Cannot ERADicate Multiple Myeloma

Research output: Contribution to journalShort surveypeer-review

31 Scopus citations

Abstract

Proteasome inhibitors are key parts of our armamentarium against multiple myeloma, but the disease can become resistant through poorly defined mechanisms. In this issue of Cancer Cell, Leung-Hagesteijn and colleagues describe XBP1s- subpopulations of tumor cells that are resistant to bortezomib and may account for therapeutic failures in the clinic.

Original languageEnglish (US)
Pages (from-to)275-277
Number of pages3
JournalCancer cell
Volume24
Issue number3
DOIs
StatePublished - Sep 9 2013

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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