Tetrachloro(trans-d,l-1,2-diaminocyclohexane)platinum(IV) complex (tetraplatin or ormaplatin) has been recognized as a potential anticancer agent. We have determined the crystal Structure of this compound by x-ray single crystal diffraction. It has a unique space group and rare molecular packing. Parameters are as follows: space group R3c (rhombohedral), a = 26.425(4) Å, α = 54.50(1)°; V = 11375Å3, Z = 36. The coordination about Pt atoms is a slightly distorted octahedron owing to the presence of the geometrically strained five-membered ring (avg. N-Pt-N angle = 82.9°). An intricate network of intermolecular hydrogen bonds holds the crystal lattice together. Three independent ormaplatin molecules surround each water molecule, forming the three shortest A⋯B contacts and thus the three strongest hydrogen bonds.
ASJC Scopus subject areas
- Inorganic Chemistry