Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neoplasms Medicine & Life Sciences
Mutation Medicine & Life Sciences
Genes Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Tumors Chemical Compounds
Genome Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Cells Chemical Compounds

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Research Output 1978 2019

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

Adhikary, S., Chakravarti, D., Terranova, C., Sengupta, I., Maitituoheti, M., Dasgupta, A., Srivastava, D. K., Ma, J., Raman, A. T., Tarco, E., Sahin, A. A., Bassett, R., Yang, F., Tapia, C., Roy, S., Rai, K. & Das, C., Dec 1 2019, In : Nature communications. 10, 1, 1398.

Research output: Contribution to journalArticle

Open Access
suppressors
Ligases
breast
Histones
Triple Negative Breast Neoplasms

Buparlisib in patients with recurrent glioblastoma harboring phosphatidylinositol 3-kinase pathway activation: An open-label, multicenter, multi-arm, phase II trial

Wen, P. Y., Touat, M., Alexander, B. M., Mellinghoff, I. K., Ramkissoon, S., McCluskey, C. S., Pelton, K., Haidar, S., Basu, S. S., Gaffey, S. C., Brown, L. E., Martinez-Ledesma, J. E., Wu, S., Kim, J., Wei, W., Park, M. A., Huse, J., Kuhn, J. G., Rinne, M. L., Colman, H. & 24 othersAgar, N. Y. R., Omuro, A. M., DeAngelis, L. M., Gilbert, M. R., de Groot, J. F., Cloughesy, T. F., Chi, A. S., Roberts, T. M., Zhao, J. J., Lee, E. Q., Nayak, L., Heath, J. R., Horky, L. L., Batchelor, T. T., Beroukhim, R., Chang, S. M., Ligon, A. H., Dunn, I. F., Koul, D., Young, G. S., Prados, M. D., Reardon, D. A., Alfred Yung, W. K. & Ligon, K. L., Mar 20 2019, In : Journal of Clinical Oncology. 37, 9, p. 741-750 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Glioblastoma
Neoplasms
Pharmacokinetics
NVP-BKM120

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Bryant, K. L., Stalnecker, C. A., Zeitouni, D., Klomp, J. E., Peng, S., Tikunov, A. P., Gunda, V., Pierobon, M., Waters, A. M., George, S. D., Tomar, G., Papke, B., Hobbs, G. A., Yan, L., Hayes, T. K., Diehl, J. N., Goode, G. D., Chaika, N. V., Wang, Y., Zhang, G. F. & 11 othersWitkiewicz, A. K., Knudsen, E. S., Petricoin, E. F., Singh, P. K., Macdonald, J. M., Tran, N. L., Lyssiotis, C. A., Ying, H., Kimmelman, A. C., Cox, A. D. & Der, C. J., Apr 1 2019, In : Nature medicine. 25, 4, p. 628-640 13 p.

Research output: Contribution to journalArticle

Autophagy
Chloroquine
Pancreatic Neoplasms
Fluxes
Adenocarcinoma