Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neoplasms Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Mutation Medicine & Life Sciences
Clinical Trials, Phase I Medicine & Life Sciences
Clinical Trials Medicine & Life Sciences
Survival Medicine & Life Sciences
Pharmacokinetics Medicine & Life Sciences

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Research Output 1977 2019

PARPI triggers the STING-dependent immune response and enhances the therapeutic efficacy of immune checkpoint blockade independent of BRCANEss

Shen, J., Zhao, W., Ju, Z., Wang, L., Peng, Y., Labrie, M., Yap, T. A., Mills, G. B. & Peng, G., Jan 15 2019, In : Cancer Research. 79, 2, p. 311-319 9 p.

Research output: Contribution to journalArticle

Therapeutic Uses
Therapeutics
DNA
Neoplasms
DNA Repair-Deficiency Disorders

Phase 1 study of the combination of vemurafenib, carboplatin, and paclitaxel in patients with BRAF-mutated melanoma and other advanced malignancies

Bhatty, M., Kato, S., Piha-Paul, S. A., Naing, A., Subbiah, V., Huang, H. J., Karp, D. D., Tsimberidou, A. M., Zinner, R. G., Hwu, W-J., Javle, M., Patel, S. P., Hu, M. I-N., Varadhachary, G. R., Conley, A. P., Ramzanali, N. M., Holley, V. R., Kurzrock, R., Meric-Bernstam, F., Kwang Chae, Y. & 3 othersKim, K. B., Falchook, G. S. & Janku, F., Feb 1 2019, In : Cancer. 125, 3, p. 463-472 10 p.

Research output: Contribution to journalArticle

Carboplatin
Paclitaxel
Melanoma
Mitogen-Activated Protein Kinase Kinases
Neoplasms
2 Citations

State-of-the-art strategies for targeting the DNA damage response in cancer

Pilie, P. G., Tang, C., Mills, G. B. & Yap, T. A., Feb 1 2019, In : Nature Reviews Clinical Oncology. 16, 2, p. 81-104 24 p.

Research output: Contribution to journalReview article

DNA Damage
Neoplasms
Therapeutics
Biomarkers
Clonal Evolution