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  • 2017

    Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

    The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

    Research output: Contribution to journal › Article › peer-review

    Open Access
    624 Scopus citations

  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    The Cancer Genome Atlas Research Network, Jun 15 2017, In: Cell. 169, 7, p. 1327-1341.e23

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1430 Scopus citations

  • Comprehensive genomic profiling of metastatic squamous cell carcinoma of the anal canal

    Morris, V., Rao, X., Pickering, C., Foo, W. C., Rashid, A., Eterovic, K., Kim, T., Chen, K., Wang, J., Shaw, K. & Eng, C., Nov 2017, In: Molecular Cancer Research. 15, 11, p. 1542-1550 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations

  • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

    Robertson, A. G., Kim, J., Al-Ahmadie, H., Bellmunt, J., Guo, G., Cherniack, A. D., Hinoue, T., Laird, P. W., Hoadley, K. A., Akbani, R., Castro, M. A. A., Gibb, E. A., Kanchi, R. S., Gordenin, D. A., Shukla, S. A., Sanchez-Vega, F., Hansel, D. E., Czerniak, B. A., Reuter, V. E., Su, X., & 153 othersde Sa Carvalho, B., Chagas, V. S., Mungall, K. L., Sadeghi, S., Pedamallu, C. S., Lu, Y., Klimczak, L. J., Zhang, J., Choo, C., Ojesina, A. I., Bullman, S., Leraas, K. M., Lichtenberg, T. M., Wu, C. J., Schultz, N., Getz, G., Meyerson, M., Mills, G. B., McConkey, D. J., Albert, M., Alexopoulou, I., Ally, A., Antic, T., Aron, M., Balasundaram, M., Bartlett, J., Baylin, S. B., Beaver, A., Birol, I., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., Brooks, D., Broom, B. M., Bshara, W., Burks, E., Cárcano, F. M., Carlsen, R., Carvalho, A. L., Castle, E. P., Castro, P., Catto, J. W., Chesla, D. W., Chuah, E., Chudamani, S., Cortessis, V. K., Cottingham, S. L., Crain, D., Curley, E., Daneshmand, S., Demchok, J. A., Dhalla, N., Djaladat, H., Eckman, J., Egea, S. C., Engel, J., Felau, I., Ferguson, M. L., Gardner, J., Gastier-Foster, J. M., Gerken, M., Gomez-Fernandez, C. R., Harr, J., Hartmann, A., Herbert, L. M., Ho, T. H., Holt, R. A., Hutter, C. M., Jones, S. J. M., Jorda, M., Kahnoski, R. J., Kasaian, K., Kwiatkowski, D. J., Lai, P. H., Lane, B. R., Lerner, S. P., Liu, J., Lolla, L., Lotan, Y., Lucchesi, F. R., Ma, Y., Machado, R. D., Maglinte, D. T., Mallery, D., Marra, M. A., Martin, S. E., Mayo, M., Meraney, A., Moinzadeh, A., Moore, R. A., Mora Pinero, E. M., Morris, S., Morrison, C., Mungall, A. J., Myers, J. B., Naresh, R., O'Donnell, P. H., Parekh, D. J., Parfitt, J., Paulauskis, J. D., Sekhar Pedamallu, C., Penny, R. J., Pihl, T., Porten, S., Quintero-Aguilo, M. E., Ramirez, N. C., Rathmell, W. K., Rieger-Christ, K., Saller, C., Salner, A., Sandusky, G., Scapulatempo, C. N., Schein, J. E., Schuckman, A. K., Shelton, C., Shelton, T., Simko, J., Singh, P., Sipahimalani, P., Smith, N. D., Sofia, H. J., Sorcini, A., Stanton, M. L., Steinberg, G. D., Stoehr, R., Su, X., Sullivan, T., Sun, Q., Tam, A., Tarnuzzer, R., Tarvin, K., Taubert, H., Thiessen, N., Thorne, L., Tse, K., Tucker, K., Van Den Berg, D. J., van Kessel, K. E., Wach, S., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wise, L., Wong, T., Wu, Y., Yang, L., Zach, L. A., Zenklusen, J. C., Zhang, J., Zmuda, E. & Zwarthoff, E. C., Oct 19 2017, In: Cell. 171, 3, p. 540-556.e25

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1467 Scopus citations

  • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

    Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J., & 187 othersAsa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In: Cancer cell. 31, 2, p. 181-193 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    500 Scopus citations

  • Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

    Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In: Cell Systems. 4, 1, p. 73-83.e10

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • Corilagin sensitizes epithelial ovarian cancer to chemotherapy by inhibiting Snail-glycolysis pathways

    Jia, L., Zho, J., Zhao, H., Yanjin, H., Lv, M., Zhao, N., Zheng, Z., Lu, Y., Ming, Y. & Yu, Y., Oct 2017, In: Oncology reports. 38, 4, p. 2464-2470 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • CTNNB1 (beta-catenin) mutation identifies low grade, early stage endometrial cancer patients at increased risk of recurrence

    Kurnit, K. C., Kim, G. N., Fellman, B. M., Urbauer, D. L., Mills, G. B., Zhang, W. & Broaddus, R. R., Jul 1 2017, In: Modern Pathology. 30, 7, p. 1032-1041 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    209 Scopus citations

  • Development and validation of an ultradeep next-generation sequencing assay for testing of plasma cell-free DNA from patients with advanced cancer

    Janku, F., Zhang, S., Waters, J., Liu, L., Huang, H. J., Subbiah, V., Hong, D. S., Karp, D. D., Fu, S., Cai, X., Ramzanali, N. M., Madwani, K., Cabrilo, G., Andrews, D. L., Zhao, Y., Javle, M., Kopetz, E. S., Luthra, R., Kim, H. J., Gnerre, S., & 11 othersSatya, R. V., Chuang, H. Y., Kruglyak, K. M., Toung, J., Zhao, C., Shen, R., Heymach, J. V., Meric-Bernstam, F., Mills, G. B., Fan, J. B. & Salathia, N. S., Sep 15 2017, In: Clinical Cancer Research. 23, 18, p. 5648-5656 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Dynamic Organization of lncRNA and Circular RNA Regulators Collectively Controlled Cardiac Differentiation in Humans

    Li, Y., Zhang, J., Huo, C., Ding, N., Li, J., Xiao, J., Lin, X., Cai, B., Zhang, Y. & Xu, J., Oct 2017, In: EBioMedicine. 24, p. 137-146 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    67 Scopus citations

  • Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer

    Lu, H., Villafane, N., Dogruluk, T., Grzeskowiak, C. L., Kong, K., Tsang, Y. H., Zagorodna, O., Pantazi, A., Yang, L., Neill, N. J., Kim, Y. W., Creighton, C. J., Verhaak, R. G., Mills, G. B., Park, P. J., Kucherlapati, R. & Scott, K. L., Jul 1 2017, In: Cancer Research. 77, 13, p. 3502-3512 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Epigenetic regulation of KPC1 ubiquitin ligase affects the NF-κB pathway in melanoma

    Iida, Y., Ciechanover, A., Marzese, D. M., Hata, K., Bustos, M., Ono, S., Wang, J., Salomon, M. P., Tran, K., Lam, S., Hsu, S., Nelson, N., Kravtsova-Ivantsiv, Y., Mills, G. B., Davies, M. A. & Hoon, D. S. B., Aug 15 2017, In: Clinical Cancer Research. 23, 16, p. 4831-4842 12 p.

    Research output: Contribution to journal › Article › peer-review

    27 Scopus citations

  • Establishment of patient-derived tumor xenograft models of epithelial ovarian cancer for preclinical evaluation of novel therapeutics

    Liu, J. F., Palakurthi, S., Zeng, Q., Zhou, S., Ivanova, E., Huang, W., Zervantonakis, I. K., Selfors, L. M., Shen, Y., Pritchard, C. C., Zheng, M., Adleff, V., Papp, E., Piao, H., Novak, M., Fotheringham, S., Wulf, G. M., English, J., Kirschmeier, P. T., Velculescu, V. E., & 6 othersPaweletz, C., Mills, G. B., Livingston, D. M., Brugge, J. S., Matulonis, U. A. & Drapkin, R., Mar 1 2017, In: Clinical Cancer Research. 23, 5, p. 1263-1273 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    91 Scopus citations

  • Estrogen Replacement Reduces Risk and Increases Survival Times of Women With Hepatocellular Carcinoma

    Hassan, M. M., Botrus, G., Abdel-Wahab, R., Wolff, R. A., Li, D., Tweardy, D., Phan, A. T., Hawk, E., Javle, M., Lee, J. S., Torres, H. A., Rashid, A., Lenzi, R., Hassabo, H. M., Abaza, Y., Shalaby, A. S., Lacin, S., Morris, J., Patt, Y. Z., Amos, C. I., & 4 othersKhaderi, S. A., Goss, J. A., Jalal, P. K. & Kaseb, A. O., Nov 2017, In: Clinical Gastroenterology and Hepatology. 15, 11, p. 1791-1799 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    78 Scopus citations

  • Explore, visualize, and analyze functional cancer proteomic data using the cancer proteome atlas

    Li, J., Akbani, R., Zhao, W., Lu, Y., Weinstein, J. N., Mills, G. B. & Liang, H., Nov 1 2017, In: Cancer Research. 77, 21, p. e51-e54

    Research output: Contribution to journal › Article › peer-review

    Open Access
    75 Scopus citations

  • Genomic analysis of exceptional responder to regorafenib in treatment-refractory metastatic rectal cancer: A case report and review of the literature

    Korphaisarn, K., Loree, J. M., Nguyen, V., Coulson, R., Holla, V., Litzenburger, B. C., Chen, K., Mills, G. B., Maru, D. M., Meric-Bernstan, F., Shaw, K. R. M. & Kopetz, S., 2017, In: Oncotarget. 8, 34, p. 57882-57888 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Genomic analysis of thymic epithelial tumors identifies novel subtypes associated with distinct clinical features

    Lee, H. S., Jang, H. J., Shah, R., Yoon, D., Hamaji, M., Wald, O., Lee, J. S., Sugarbaker, D. J. & Burt, B. M., Aug 15 2017, In: Clinical Cancer Research. 23, 16, p. 4855-4864 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers

    Ock, C. Y., Hwang, J. E., Keam, B., Kim, S. B., Shim, J. J., Jang, H. J., Park, S., Sohn, B. H., Cha, M., Ajani, J. A., Kopetz, S., Lee, K. W., Kim, T. M., Heo, D. S. & Lee, J. S., Dec 1 2017, In: Nature communications. 8, 1, 1050.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    95 Scopus citations

  • HNF1B loss exacerbates the development of chromophobe renal cell carcinomas

    Sun, M., Tong, P., Kong, W., Dong, B., Huang, Y., Park, I. Y., Zhou, L., Liu, X. D., Ding, Z., Zhang, X., Bai, S., German, P., Powell, R., Wang, Q., Tong, X., Tannir, N. M., Matin, S. F., Rathmell, W. K., Fuller, G. N., McCutcheon, I. E., & 3 othersWalker, C. L., Wang, J. & Jonasch, E., Oct 1 2017, In: Cancer Research. 77, 19, p. 5313-5326 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations

  • Hormonal based treatment of ovarian anaplastic ependymoma with anastrozole

    Gorski, J. W., Taylor, J. S., Zhang, J., Liu, J. & Jazaeri, A. A., May 1 2017, In: Gynecologic Oncology Reports. 20, p. 93-96 4 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • HSP70 inhibition synergistically enhances the effects of magnetic fluid hyperthermia in ovarian cancer

    Court, K. A., Hatakeyama, H., Wu, S. Y., Lingegowda, M. S., Rodríguez-Aguayo, C., López-Berestein, G., Ju-Seog, L., Rinaldi, C., Juan, E. J., Sood, A. K. & Torres-Lugo, M., May 1 2017, In: Molecular cancer therapeutics. 16, 5, p. 966-976 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • HSP90 Shapes the Consequences of Human Genetic Variation

    Karras, G. I., Yi, S., Sahni, N., Fischer, M., Xie, J., Vidal, M., D'Andrea, A. D., Whitesell, L. & Lindquist, S., Feb 23 2017, In: Cell. 168, 5, p. 856-866.e12

    Research output: Contribution to journal › Article › peer-review

    Open Access
    77 Scopus citations

  • Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

    McGrail, D. J., Lin, C. C. J., Garnett, J., Liu, Q., Mo, W., Dai, H., Lu, Y., Yu, Q., Ju, Z., Yin, J., Vellano, C. P., Hennessy, B., Mills, G. B. & Lin, S. Y., Dec 1 2017, In: npj Systems Biology and Applications. 3, 1, 8.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer

    Weiler, S. M. E., Pinna, F., Wolf, T., Lutz, T., Geldiyev, A., Sticht, C., Knaub, M., Thomann, S., Bissinger, M., Wan, S., Rössler, S., Becker, D., Gretz, N., Lang, H., Bergmann, F., Ustiyan, V., Kalin, T. V., Singer, S., Lee, J. S., Marquardt, J. U., & 3 othersSchirmacher, P., Kalinichenko, V. V. & Breuhahn, K., Jun 2017, In: Gastroenterology. 152, 8, p. 2037-2051.e22

    Research output: Contribution to journal › Article › peer-review

    109 Scopus citations

  • In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons

    Chung, C. Y., Khurana, V., Yi, S., Sahni, N., Loh, K. H., Auluck, P. K., Baru, V., Udeshi, N. D., Freyzon, Y., Carr, S. A., Hill, D. E., Vidal, M., Ting, A. Y. & Lindquist, S., Feb 22 2017, In: Cell Systems. 4, 2, p. 242-250.e4

    Research output: Contribution to journal › Article › peer-review

    Open Access
    83 Scopus citations

  • Integrated genomic analysis of recurrence-associated small non-coding RNAs in oesophageal cancer

    Jang, H. J., Lee, H. S., Burt, B. M., Lee, G. K., Yoon, K. A., Park, Y. Y., Sohn, B. H., Kim, S. B., Kim, M. S., Lee, J. M., Joo, J., Kim, S. C., Yun, J. S., Na, K. J., Choi, Y. L., Park, J. L., Kim, S. Y., Lee, Y. S., Han, L., Liang, H., & 6 othersMak, D., Burks, J. K., Zo, J. I., Sugarbaker, D. J., Shim, Y. M. & Lee, J. S., Feb 1 2017, In: Gut. 66, 2, p. 215-225 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Integrated genomic and molecular characterization of cervical cancer

    The Cancer Genome Atlas Research Network, Mar 16 2017, In: Nature. 543, 7645, p. 378-384 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    985 Scopus citations

  • Integrated genomic characterization of oesophageal carcinoma

    The Cancer Genome Atlas Research Network, Jan 12 2017, In: Nature. 541, 7636, p. 169-174 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1195 Scopus citations

  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B., & 251 othersAkbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In: Cancer cell. 32, 2, p. 185-203.e13

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1172 Scopus citations

  • Integrated Molecular Characterization of Uterine Carcinosarcoma

    Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., & 130 othersBaylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In: Cancer cell. 31, 3, p. 411-423 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    273 Scopus citations

  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

    Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L., & 150 othersChang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In: Cancer cell. 32, 2, p. 204-220.e15

    Research output: Contribution to journal › Article › peer-review

    Open Access
    563 Scopus citations

  • Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome

    Aure, M. R., Vitelli, V., Jernström, S., Kumar, S., Krohn, M., Due, E. U., Haukaas, T. H., Leivonen, S. K., Vollan, H. K. M., Lüders, T., Rødland, E., Vaske, C. J., Zhao, W., Møller, E. K., Nord, S., Giskeødegård, G. F., Bathen, T. F., Caldas, C., Tramm, T., Alsner, J., & 26 othersOvergaard, J., Geisler, J., Bukholm, I. R. K., Naume, B., Schlichting, E., Sauer, T., Mills, G. B., Kåresen, R., Mælandsmo, G. M., Lingjærde, O. C., Frigessi, A., Kristensen, V. N., Børresen-Dale, A. L., Sahlberg, K. K., Borgen, E., Engebråten, O., Fodstad, Ø., Fritzman, B., Garred, Ø., Geitvik, G. A., Langerød, A., Hofvind, S., Russnes, H. G., Skjerven, H. K., Sørlie, T. & OSBREAC, Mar 29 2017, In: Breast Cancer Research. 19, 1, 44.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    70 Scopus citations

  • Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

    CONSORTIA, Mar 14 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    351 Scopus citations

  • Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells

    Kang, D. H., Lee, D. J., Lee, S., Lee, S. Y., Jun, Y., Kim, Y., Kim, Y., Lee, J. S., Lee, D. K., Lee, S., Jho, E. H., Yu, D. Y. & Kang, S. W., Dec 1 2017, In: Nature communications. 8, 1, 40.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Jab1/Csn5–thioredoxin signaling in relapsed acute monocytic leukemia under oxidative stress

    Zhou, F., Pan, Y., Wei, Y., Zhang, R., Bai, G., Shen, Q., Meng, S., Le, X. F., Andreeff, M. & Claret, F. X., Aug 1 2017, In: Clinical Cancer Research. 23, 15, p. 4450-4461 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism

    Zeng, Q., Chen, J., Li, Y., Werle, K. D., Zhao, R. X., Quan, C. S., Wang, Y. S., Zhai, Y. X., Wang, J. W., Youssef, M., Cui, R., Liang, J., Genovese, N., Chow, L. T., Li, Y. L. & Xu, Z. X., Mar 2 2017, In: Oncogene. 36, 9, p. 1245-1255 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations

  • Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells

    Yuan, Y., Du, Y., Hu, X. Y., Liu, M. Y., Du, J. K., Liu, X. M., Yu, H. E., Wang, T. Z., Pu, J. X., Zhong, Q. & Zou, Q. F., Mar 2017, In: Oncology Letters. 13, 3, p. 1672-1680 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • Loss-of-function screens of druggable targetome against cancer stem-like cells

    Song, M., Lee, H., Nam, M. H., Jeong, E., Kim, S., Hong, Y., Kim, N., Yim, H. Y., Yoo, Y. J., Kim, J. S., Kim, J. S., Cho, Y. Y., Mills, G. B., Kim, W. Y. & Yoon, S., Feb 2017, In: FASEB Journal. 31, 2, p. 625-935 311 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Loss of the novel mitochondrial protein fam210b promotes metastasis via pdk4-dependent metabolic reprogramming

    Sun, S., Liu, J., Zhao, M., Han, Y., Chen, P., Mo, Q., Wang, B., Chen, G., Fang, Y., Tian, Y., Zhou, J., Ma, D., Gao, Q. & Wu, P., 2017, In: Cell Death and Disease. 8, 6, e2870.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations

  • Macrophages facilitate resistance to anti-VEGF therapy by altered VEGFR expression

    Dalton, H. J., Pradeep, S., McGuire, M., Hailemichael, Y., Ma, S., Lyons, Y., Armaiz-Pena, G. N., Previs, R. A., Hansen, J. M., Rupaimoole, R., Gonzalez-Villasana, V., Cho, M. S., Wu, S. Y., Mangala, L. S., Jennings, N. B., Hu, W., Langley, R., Mu, H., Andreeff, M., Bar-Eli, M., & 5 othersOverwijk, W., Ram, P., Lopez-Berestein, G., Coleman, R. L. & Sood, A. K., Nov 15 2017, In: Clinical Cancer Research. 23, 22, p. 7034-7046 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    70 Scopus citations

  • Marsdenia tenacissima extract overcomes Axl- and Metmediated erlotinib and gefitinib cross-resistance in non-small cell lung cancer cells

    Han, S. Y., Zhao, W., Han, H. B., Sun, H., Xue, D., Jiao, Y. N., He, X. R., Jiang, S. T. & Li, P. P., 2017, In: Oncotarget. 8, 34, p. 56893-56905 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • MicroPET/CT imaging of AXL downregulation by HSP90 inhibition in triple-negative breast cancer

    Wang, W., Zhao, J., Wen, X., Chun-Jen Lin, C., Li, J., Huang, Q., Yu, Y., Lin, S. Y. & Li, C., May 14 2017, In: Contrast Media and Molecular Imaging. 2017, 1686525.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • MicroRNA-31 suppresses the self-renewal capability of α2δ1+ liver tumor-initiating cells by targeting ISL1

    Zhang, Y., Zhao, W., Han, H., Li, S., Chen, D. & Zhang, Z., 2017, In: Oncotarget. 8, 50, p. 87647-87657 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • miRNA-miRNA crosstalk: From genomics to phenomics

    Xu, J., Shao, T., Ding, N., Li, Y. & Li, X., Nov 1 2017, In: Briefings in bioinformatics. 18, 6, p. 1002-1011 10 p.

    Research output: Contribution to journal › Article › peer-review

    27 Scopus citations

  • Molecular heterogeneity at the network level: High-dimensional testing, clustering and a TCGA case study

    Städler, N., Dondelinger, F., Hill, S. M., Akbani, R., Lu, Y., Mills, G. B. & Mukherjee, S., Sep 15 2017, In: Bioinformatics. 33, 18, p. 2890-2896 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Multiplatform-based molecular subtypes of non-small-cell lung cancer

    Chen, F., Zhang, Y., Parra, E., Rodriguez, J., Behrens, C., Akbani, R., Lu, Y., Kurie, J. M., Gibbons, D. L., Mills, G. B., Wistuba, I. I. & Creighton, C. J., Mar 1 2017, In: Oncogene. 36, 10, p. 1384-1393 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    94 Scopus citations

  • Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer

    Kang, M. H., Jeong, K. J., Kim, W. Y., Lee, H. J., Gong, G., Suh, N., Gyrffy, B., Kim, S., Jeong, S. Y., Mills, G. B. & Park, Y. Y., Mar 23 2017, In: Oncogene. 36, 12, p. 1745-1752 8 p.

    Research output: Contribution to journal › Article › peer-review

    53 Scopus citations

  • Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer

    Gao, R., Kim, C., Sei, E., Foukakis, T., Crosetto, N., Chan, L. K., Srinivasan, M., Zhang, H., Meric-Bernstam, F. & Navin, N., Dec 1 2017, In: Nature communications. 8, 1, 228.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    88 Scopus citations

  • Next-Generation Sequencing and Result Interpretation in Clinical Oncology: Challenges of Personalized Cancer Therapy

    Khotskaya, Y. B., Mills, G. B. & Mills Shaw, K. R., Jan 14 2017, In: Annual Review of Medicine. 68, p. 113-125 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

    Zoeller, J. J., Bronson, R. T., Selfors, L. M., Mills, G. B. & Brugge, J. S., Dec 1 2017, In: npj Breast Cancer. 3, 1, 18.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations