Eun-Kyoung Breuer

Research output

Research output per year 2011 2012 2013 2015 2016 2018 2019

• 11 Article
• 4 Review article
• 3 Editorial

Research output per year

Research output per year

Search results

• 2019

  Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling

  Breuer, E. K., Fukushiro-Lopes, D., Dalheim, A., Burnette, M., Zartman, J., Kaja, S., Wells, C., Campo, L., Curtis, K. J., Romero-Moreno, R., Littlepage, L. E., Niebur, G. L., Hoskins, K., Nishimura, M. I. & Gentile, S., Mar 1 2019, In: Cell Death and Disease. 10, 3, 180.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Catenins 100%
  • Potassium Channels 90%
  • 1,3-bis(2-hydroxy-5-trifluoromethylphenyl)urea 65%
  • Cell Movement 51%
  • Breast Neoplasms 50%
  50 Scopus citations
• 2018

  Combination treatment of polo-like kinase 1 and tankyrase-1 inhibitors enhances anticancer effect in triple-negative breast cancer cells

  Ha, G. H., Kim, D. Y., Breuer, E. K. & Kim, C. K., Mar 2018, In: Anticancer research. 38, 3, p. 1303-1310 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tankyrases 100%
  • polo-like kinase 1 89%
  • Triple Negative Breast Neoplasms 71%
  • Apoptosis 15%
  • Cell Migration Assays 11%
  20 Scopus citations

• Inhibition of TACC3 by a small molecule inhibitor in breast cancer

  Campo, L. & Breuer, E. K., Apr 15 2018, In: Biochemical and biophysical research communications. 498, 4, p. 1085-1092 8 p.

  Research output: Contribution to journal › Article › peer-review

  • KHS101 100%
  • Breast Neoplasms 45%
  • Protein 29%
  • Proteins 26%
  • DNA Damage 25%
  15 Scopus citations

• Negative regulation of BRCA1 by transforming acidic coiled-coil protein 3 (TACC3)

  Kim, J. L., Ha, G. H., Campo, L. & Breuer, E. K., Feb 5 2018, In: Biochemical and biophysical research communications. 496, 2, p. 633-640 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Breast Neoplasms 100%
  • Genomic Instability 86%
  • Protein 80%
  • Proteins 72%
  • Breast 59%
  8 Scopus citations

• Preclinical study of a Kv11.1 potassium channel activator as antineoplastic approach for breast cancer

  Fukushiro-Lopes, D. F., Hegel, A. D., Rao, V., Wyatt, D., Baker, A., Breuer, E. K., Osipo, C., Zartman, J. J., Burnette, M., Kaja, S., Kouzoukas, D., Burris, S., Keith Jones, W. & Gentile, S., 2018, In: Oncotarget. 9, 3, p. 3321-3337 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Potassium Channels 100%
  • 1,3-bis(2-hydroxy-5-trifluoromethylphenyl)urea 90%
  • Antineoplastic Agents 83%
  • Breast Neoplasms 55%
  • Neoplasms 28%
  35 Scopus citations
• 2017

  The role of Rak in the regulation of stability and function of BRCA1

  Kim, J. L., Ha, G. H., Campo, L., Denning, M. F., Patel, T. B., Osipo, C., Lin, S. Y. & Breuer, E. K., Oct 17 2017, In: Oncotarget. 8, 49, p. 86799-86815 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • BRCA1 Protein 100%
  • Genomic Instability 73%
  • Poly(ADP-ribose) Polymerase Inhibitors 29%
  • Breast Neoplasms 28%
  • Protein Stability 26%
  9 Scopus citations
• 2016

  Predictors and Modulators of Synthetic Lethality: An Update on PARP Inhibitors and Personalized Medicine

  Murata, S., Zhang, C., Finch, N., Zhang, K., Campo, L. & Breuer, E. K., 2016, In: BioMed research international. 2016, 2346585.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Synthetic Lethal Mutations 100%
  • Poly(ADPribose) 93%
  • Poly(ADP-ribose) Polymerase Inhibitors 89%
  • Precision Medicine 73%
  • olaparib 41%
  36 Scopus citations

• Targeting defective DNA damage response signaling

  Campo, L. & Breuer, E. K., Feb 1 2016, In: Current Drug Targets. 17, 2, p. 138 1 p.

  Research output: Contribution to journal › Editorial › peer-review
• 2015

  EMT-inducing molecular factors in gynecological cancers

  Campo, L., Zhang, C. & Breuer, E. K., 2015, In: BioMed research international. 2015, 420891.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Epithelial-Mesenchymal Transition 100%
  • Neoplasms 31%
  • Vulva 23%
  • Papillomaviridae 23%
  • Fallopian Tubes 23%
  20 Scopus citations

• FAK mediates a compensatory survival signal parallel to PI3K-AKT in PTEN-Null T-ALL cells

  You, D., Xin, J., Volk, A., Wei, W., Schmidt, R., Scurti, G., Nand, S., Breuer, E. K., Kuo, P. C., Breslin, P., Kini, A. R., Nishimura, M. I., Zeleznik-Le, N. J. & Zhang, J., Mar 31 2015, In: Cell Reports. 10, 12, p. 2055-2068 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphatidylinositol 100%
  • Phosphatidylinositol 3-Kinase 84%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 81%
  • Survival 45%
  • Disorder 35%
  46 Scopus citations

• TACC3 deregulates the DNA damage response and confers sensitivity to radiation and PARP inhibition

  Ha, G. H., Kim, J. L., Petersson, A., Oh, S., Denning, M. F., Patel, T. & Breuer, E. K., Mar 26 2015, In: Oncogene. 34, 13, p. 1667-1678 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Poly(ADP-ribose) Polymerases 100%
  • Radiation Tolerance 96%
  • DNA Damage 73%
  • Proteins 30%
  • Genomic Instability 23%
  18 Scopus citations

• TACC3 in personalized medicine

  Murata, S., Campo, L. & Breuer, E. K., 2015, In: Oncoscience. 2, 10, p. 847-848 2 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
• 2013

  TACC3 Is Essential for EGF-Mediated EMT in Cervical Cancer

  Ha, G. H., Kim, J. L. & Breuer, E. K. Y., Aug 1 2013, In: PloS one. 8, 8, e70353.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • uterine cervical neoplasms 100%
  • epidermal growth factor 80%
  • epidermal growth factor receptors 79%
  • Epithelial-Mesenchymal Transition 73%
  • Epidermal Growth Factor 69%
  48 Scopus citations

• TACC3 promotes epithelial-mesenchymal transition (EMT) through the activation of PI3K/Akt and ERK signaling pathways

  Ha, G. H., Park, J. S. & Breuer, E. K. Y., May 10 2013, In: Cancer Letters. 332, 1, p. 63-73 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Signal-Regulated MAP Kinases 100%
  • Epithelial-Mesenchymal Transition 95%
  • Phosphatidylinositol 3-Kinase 93%
  • Protein Kinases 85%
  • Proteins 33%
  99 Scopus citations

• Transforming acidic coiled-coil proteins (TACCs) in human cancer

  Ha, G. H., Kim, J. L. & Breuer, E. K. Y., Aug 9 2013, In: Cancer Letters. 336, 1, p. 24-33 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Centrosome 100%
  • Microtubules 62%
  • Proteins 35%
  • Neoplasms 30%
  • Genomic Instability 17%
  51 Scopus citations
• 2012

  Biochemical pathways in cancer

  Breuer, E. K. Y., Murph, M. M. & Craven, R. J., 2012, In: Biochemistry Research International. 268504.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Mitotic kinases and p53 signaling

  Ha, G. H. & Breuer, E. K. Y., 2012, In: Biochemistry Research International. 195903.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Phosphotransferases 61%
  • Error 59%
  • Aneuploidy 17%
  • Mitosis 15%
  • Spindle Apparatus 9%
  10 Scopus citations
• 2011

  ZNF668 functions as a tumor suppressor by regulating p53 stability and function in breast cancer

  Hu, R., Peng, G., Dai, H., Breuer, E. K., Stemke-Hale, K., Li, K., Gonzalez-Angulo, A. M., Mills, G. B. & Lin, S. Y., Oct 15 2011, In: Cancer Research. 71, 20, p. 6524-6534 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zinc Fingers 100%
  • Breast Neoplasms 56%
  • Proteins 32%
  • Neoplasms 28%
  • Protein Deficiency 16%
  26 Scopus citations