Hiroki Torikai

2020

Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering

Zong, S., Mi, T., Flores, L. G., Alpert, A., Olivares, S., Patel, K., Maiti, S., McNamara, G., Cooper, L. J. N. & Torikai, H., Feb 1 2020, In: PloS one. 15, 2, e0228112.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2016

CD62L⁺ NKT cells have prolonged persistence and antitumor activity in vivo

Tian, G., Courtney, A. N., Jena, B., Heczey, A., Liu, D., Marinova, E., Guo, L., Xu, X., Torikai, H., Mo, Q., Dotti, G., Cooper, L. J. & Metelitsa, L. S., Jun 1 2016, In: Journal of Clinical Investigation. 126, 6, p. 2341-2355 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

118 Scopus citations

Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application

Torikai, H., Mi, T., Gragert, L., Maiers, M., Najjar, A., Ang, S., Maiti, S., Dai, J., Switzer, K. C., Huls, H., Dulay, G. P., Reik, A., Rebar, E. J., Holmes, M. C., Gregory, P. D., Champlin, R. E., Shpall, E. J. & Cooper, L. J. N., Feb 23 2016, In: Scientific reports. 6, 21757.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Redirecting specificity of t cells using the Sleeping Beauty system to express chimeric antigen receptors by mix-and-matching of V_L and V_H domains targeting CD123⁺ tumors

Thokala, R., Olivares, S., Mi, T., Maiti, S., Deniger, D., Huls, H., Torikai, H., Singh, H., Champlin, R. E., Laskowski, T., McNamara, G. & Cooper, L. J. N., Aug 2016, In: PloS one. 11, 8, e0159477.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

Redirecting T-cell specificity to EGFR using mRNA to self-limit expression of chimeric antigen receptor

Caruso, H. G., Torikai, H., Zhang, L., Maiti, S., Dai, J., Do, K. A., Singh, H., Huls, H., Lee, D. A., Champlin, R. E., Heimberger, A. B. & Cooper, L. J. N., 2016, In: Journal of Immunotherapy. 39, 5, p. 205-217 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Targeting B-cell malignancies through human B-cell receptor specific CD4⁺ T cells

Weng, J., Baio, F. E., Moriarty, K. E., Torikai, H., Wang, H., Liu, Z., Maiti, S. N., Gwak, D., Popescu, M. S., Cha, S. C., Cooper, L. J. N., Neelapu, S. S. & Kwak, L. W., Nov 1 2016, In: OncoImmunology. 5, 11, e1232220.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2013

Sleeping beauty system to redirect T-cell specificity for human applications

Maiti, S. N., Huls, H., Singh, H., Dawson, M., Figliola, M., Olivares, S., Rao, P., Zhao, Y. J., Multani, A., Yang, G., Zhang, L., Crossland, D., Ang, S., Torikai, H., Rabinovich, B., Lee, D. A., Kebriaei, P., Hackett, P., Champlin, R. E. & Cooper, L. J. N., Feb 2013, In: Journal of Immunotherapy. 36, 2, p. 112-123 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Toward eliminating HLA class i expression to generate universal cells from allogeneic donors

Torikai, H., Reik, A., Soldner, F., Warren, E. H., Yuen, C., Zhou, Y., Crossland, D. L., Huls, H., Littman, N., Zhang, Z., Tykodi, S. S., Kebriaei, P., Lee, D. A., Miller, J. C., Rebar, E. J., Holmes, M. C., Jaenisch, R., Champlin, R. E., Gregory, P. D. & Cooper, L. J. N., 2013, In: Blood. 122, 8, p. 1341-1349 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

230 Scopus citations

2012

A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR

Torikai, H., Reik, A., Liu, P. Q., Zhou, Y., Zhang, L., Maiti, S., Huls, H., Miller, J. C., Kebriaei, P., Rabinovitch, B., Lee, D. A., Champlin, R. E., Bonini, C., Naldini, L., Rebar, E. J., Gregory, P. D., Holmes, M. C. & Cooper, L. J. N., Jun 14 2012, In: Blood. 119, 24, p. 5697-5705 9 p.

Research output: Contribution to journal › Article › peer-review

404 Scopus citations

Autophagy Creates a CTL Epitope That Mimics Tumor-Associated Antigens

Demachi-Okamura, A., Torikai, H., Akatsuka, Y., Miyoshi, H., Yoshimori, T. & Kuzushima, K., Oct 11 2012, In: PloS one. 7, 10, e47126.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

HapMap SNP Scanner: An online program to mine SNPs responsible for cell phenotype

Yamamura, T., Hikita, J., Bleakley, M., Hirosawa, T., Sato-Otsubo, A., Torikai, H., Hamajima, T., Nannya, Y., Demachi-Okamura, A., Maruya, E., Saji, H., Yamamoto, Y., Takahashi, T., Emi, N., Morishima, Y., Kodera, Y., Kuzushima, K., Riddell, S. R., Ogawa, S. & Akatsuka, Y., Aug 2012, In: Tissue Antigens. 80, 2, p. 119-125 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2011

Mismatched human leukocyte antigen class II-restricted CD8⁺ cytotoxic T cells may mediate selective graft-versus-leukemia effects following allogeneic hematopoietic cell transplantation

Hirosawa, T., Torikai, H., Yanagisawa, M., Kamei, M., Imahashi, N., Demachi-Okamura, A., Tanimoto, M., Shiraishi, K., Ito, M., Miyamura, K., Shibata, K., Kikkawa, F., Morishima, Y., Takahashi, T., Emi, N., Kuzushima, K. & Akatsuka, Y., Jul 2011, In: Cancer science. 102, 7, p. 1281-1286 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2010

A high throughput microelectroporation device to introduce a chimeric antigen receptor to redirect the specificity of human T cells

Choi, Y., Yuen, C., Maiti, S. N., Olivares, S., Gibbons, H., Huls, H., Raphael, R., Killian, T. C., Stark, D. J., Lee, D. A., Torikai, H., Monticello, D., Kelly, S. S., Kebriaei, P., Champlin, R. E., Biswal, S. L. & Cooper, L. J. N., Oct 2010, In: Biomedical Microdevices. 12, 5, p. 855-863 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2009

BCR-ABL promotes neutrophil differentiation in the chronic phase of chronic myeloid leukemia by downregulating c-Jun expression

Kobayashi, S., Kimura, F., Ikeda, T., Osawa, Y., Torikai, H., Kobayashi, A., Sato, K. & Motoyoshi, K., Sep 2009, In: Leukemia. 23, 9, p. 1622-1627 6 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

HapMap scanning of novel human minor histocompatibility antigens

Kamei, M., Nannya, Y., Torikai, H., Kawase, T., Taura, K., Inamoto, Y., Takahashi, T., Yazaki, M., Morishima, S., Tsujimura, K., Miyamura, K., Ito, T., Togari, H., Riddell, S. R., Kodera, Y., Morishima, Y., Takahashi, T., Kuzushima, K., Ogawa, S. & Akatsuka, Y., 2009, In: Blood. 113, 21, p. 5041-5048 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

2008

Aberrant expression of BCL2A1-restricted minor histocompatibility antigens in melanoma cells: Application for allogeneic transplantation

Torikai, H., Akatsuka, Y., Yatabe, Y., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., Jun 2008, In: International journal of hematology. 87, 5, p. 467-473 7 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Histiocytic sarcoma of the spleen: Case report of asymptomatic onset of thrombocytopenia and complex imaging features

Kobayashi, S., Kimura, F., Hama, Y., Ogura, K., Torikai, H., Kobayashi, A., Ikeda, T., Sato, K., Aida, S., Kosuda, S. & Motoyoshi, K., Jan 2008, In: International journal of hematology. 87, 1, p. 83-87 5 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Identification of human minor histocompatibility antigens based on genetic association with highly parallel genotyping of pooled DNA

Kawase, T., Nannya, Y., Torikai, H., Yamamoto, G., Onizuka, M., Morishima, S., Tsujimura, K., Miyamura, K., Kodera, Y., Morishima, Y., Takahashi, T., Kuzushima, K., Ogawa, S. & Akatsuka, Y., Mar 15 2008, In: Blood. 111, 6, p. 3286-3294 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Methicillin-resistant Staphylococcus aureus-induced pyomyositis that emerged during recovery from drug-induced pancytopenia

Kobayashi, S., Kimura, F., Ogura, K., Kobayashi, A., Torikai, H., Ikeda, T., Sato, K., Saionji, K., Ito, T., Saito, D. & Motoyoshi, K., Jan 2008, In: [Rinshō ketsueki] The Japanese journal of clinical hematology. 49, 1, p. 55-58 4 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2007

Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen

Kawase, T., Akatsuka, Y., Torikai, H., Morishima, S., Oka, A., Tsujimura, A., Miyazaki, M., Tsujimura, K., Miyamura, K., Ogawa, S., Inoko, H., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., Aug 1 2007, In: Blood. 110, 3, p. 1055-1063 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Identification of an HLA-A24-restricted cytotoxic T lymphocyte epitope from human papillomavirus type-16 E6: The combined effects of bortezomib and interferon-γ on the presentation of a cryptic epitope

Morishima, S., Akatsuka, Y., Nawa, A., Kondo, E., Kiyono, T., Torikai, H., Nakanishi, T., Ito, Y., Tsujimura, K., Iwata, K., Ito, K., Kodera, Y., Morishima, Y., Kuzushima, K. & Takahashi, T., Feb 1 2007, In: International journal of cancer. 120, 3, p. 594-604 11 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

The HLA-A 0201-restricted minor histocompatibility antigen HA-1^H peptide can also be presented by another HLA-A2 subtype, A 0206

Torikai, H., Akatsuka, Y., Miyauchi, H., Terakura, S., Onizuka, M., Tsujimura, K., Miyamura, K., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., Jul 2007, In: Bone marrow transplantation. 40, 2, p. 165-174 10 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

2006

Myeloid/NK cell precursor acute leukemia lost both CD13 and CD33 at first diagnosis

Ogura, K., Kimura, F., Kobayashi, S., Torikai, H., Ikeda, T., Sato, K. & Motoyoshi, K., Jun 2006, In: Leukemia Research. 30, 6, p. 761-763 3 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

The human cathepsin H gene encodes two novel minor histocompatibility antigen epitopes restricted by HLA-A3101 and -A3303

Torikai, H., Akatsuka, Y., Miyazaki, M., Tsujimura, A., Yatabe, Y., Kawase, T., Nakao, Y., Tsujimura, K., Motoyoshi, K., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., Aug 2006, In: British Journal of Haematology. 134, 4, p. 406-416 11 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

2005

HHV-6 encephalitis after unrelated cord blood transplantation in a patient with acute lymphoblastic leukemia

Watanabe, J. I., Ogura, K., Kobayashi, S. I., Torikai, H., Ikeda, T., Sato, K., Kimura, F. & Motoyoshi, K., Nov 10 2005, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 94, 11, p. 2388-2390 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2004

A novel HLA-A*3303-restricted minor histocompatibility antigen encoded by an unconventional open reading frame of human TMSB4Y gene

Torikai, H., Akatsuka, Y., Miyazaki, M., Warren, E. H., Oba, T., Tsujimura, K., Motoyoshi, K., Morishima, Y., Kodera, Y., Kuzushima, K. & Takahashi, T., Dec 1 2004, In: Journal of Immunology. 173, 11, p. 7046-7054 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Emergence and decrement of Ph-negative clone with trisomy 8 in CML during imatinib therapy

Kimura, F., Kobayashi, S., Ogura, K., Kobayashi, A., Torikai, H., Ikeda, T., Sato, K. & Motoyoshi, K., 2004, In: [Rinshō ketsueki] The Japanese journal of clinical hematology. 45, 9, p. 1058-1060 3 p.

Research output: Contribution to journal › Article › peer-review

Hiroki Torikai

Research output

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