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Wenbin Liu

Data Scientist

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    20092023

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    • 2009

      Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics

      Hennessy, B. T., Gonzalez-Angulo, A. M., Stemke-Hale, K., Gilcrease, M. Z., Krishnamurthy, S., Lee, J. S., Fridlyand, J., Sahin, A., Agarwal, R., Joy, C., Liu, W., Stivers, D., Baggerly, K., Carey, M., Lluch, A., Monteagudo, C., He, X., Weigman, V., Fan, C., Palazzo, J., & 7 othersHortobagyi, G. N., Nolden, L. K., Wang, N. J., Valero, V., Gray, J. W., Perou, C. M. & Mills, G. B., May 15 2009, In: Cancer Research. 69, 10, p. 4116-4124 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      720 Scopus citations

    • Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

      Liu, S., Umezu-Goto, M., Murph, M., Lu, Y., Liu, W., Zhang, F., Yu, S., Stephens, L. C., Cui, X., Murrow, G., Coombes, K., Muller, W., Hung, M. C., Perou, C. M., Lee, A. V., Fang, X. & Mills, G. B., Jun 2 2009, In: Cancer cell. 15, 6, p. 539-550 12 p.

      Research output: Contribution to journal › Article › peer-review

      325 Scopus citations

    • Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis

      Murph, M. M., Liu, W., Yu, S., Lu, Y., Hall, H., Hennessy, B. T., Lahad, J., Schaner, M., Helland, Å., Kristenen, G., Bøorresen-Dale, A. L. & Mills, G. B., May 15 2009, In: PloS one. 4, 5, e5583.

      Research output: Contribution to journal › Article › peer-review

      43 Scopus citations

    • Serial dilution curve: A new method for analysis of reverse phase protein array data

      Zhang, L., Wei, Q., Mao, L., Liu, W., Mills, G. B. & Coombes, K., Mar 2009, In: Bioinformatics. 25, 5, p. 650-654 5 p.

      Research output: Contribution to journal › Article › peer-review

      44 Scopus citations
    • 2010

      A technical assessment of the utility of reverse phase protein arrays for the study of the functional proteome in non-microdissected human breast cancers

      Hennessy, B. T., Lu, Y., Gonzalez-Angulo, A. M., Carey, M. S., Myhre, S., Ju, Z., Davies, M. A., Liu, W., Coombes, K., Meric-Bernstam, F., Bedrosian, I., McGahren, M., Agarwal, R., Zhang, F., Overgaard, J., Alsner, J., Neve, R. M., Kuo, W. L., Gray, J. W., Borresen-Dale, A. L., & 1 othersMills, G. B., Dec 2010, In: Clinical Proteomics. 6, 4, p. 129-151 23 p.

      Research output: Contribution to journal › Article › peer-review

      180 Scopus citations

    • Blasted cell line names

      Wang, J., Byers, L. A., Yordy, J. S., Liu, W., Shen, L., Baggerly, K. A., Giri, U., Myers, J. N., Ang, K. K., Story, M. D., Girard, L., Minna, J. D., Heymach, J. V. & Coombes, K. R., 2010, In: Cancer Informatics. 9, p. 251-255 5 p.

      Research output: Contribution to journal › Article › peer-review

    • Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set

      Park, E. S., Rabinovsky, R., Carey, M., Hennessy, B. T., Agarwal, R., Liu, W., Ju, Z., Deng, W., Lu, Y., Woo, H. G., Kim, S. B., Cheong, J. H., Garraway, L. A., Weinstein, J. N., Mills, G. B., Lee, J. S. & Davies, M. A., Feb 2010, In: Molecular cancer therapeutics. 9, 2, p. 257-267 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      79 Scopus citations

    • Molecular signatures and biological pathway profiles of human corneal epithelial progenitor cells

      Bian, F., Liu, W., Yoon, K. C., Lu, R., Zhou, N., Ma, P., Pflugfelder, S. C. & Li, D. Q., Jul 2010, In: International Journal of Biochemistry and Cell Biology. 42, 7, p. 1142-1153 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      29 Scopus citations
    • 2011

      Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer

      Gonzalez-Angulo, A. M., Hennessy, B. T., Meric-Bernstam, F., Sahin, A., Liu, W., Ju, Z., Carey, M. S., Myhre, S., Speers, C., Deng, L., Broaddus, R., Lluch, A., Aparicio, S., Brown, P., Pusztai, L., Symmans, W. F., Alsner, J., Overgaard, J., Borresen-Dale, A. L., Hortobagyi, G. N., & 2 othersCoombes, K. R. & Mills, G. B., 2011, In: Clinical Proteomics. 8, 1, 11.

      Research output: Contribution to journal › Article › peer-review

      81 Scopus citations
    • 2012

      An efficient procedure for protein extraction from formalin-fixed, Paraffin-embedded tissues for reverse phase protein arrays

      Guo, H., Liu, W., Ju, Z., Tamboli, P., Jonasch, E., Mills, G. B., Lu, Y., Hennessy, B. T. & Tsavachidou, D., Sep 24 2012, In: Proteome Science. 10, 1, 56.

      Research output: Contribution to journal › Article › peer-review

      51 Scopus citations

    • Comprehensive molecular portraits of human breast tumours

      Koboldt, D. C., Fulton, R. S., McLellan, M. D., Schmidt, H., Kalicki-Veizer, J., McMichael, J. F., Fulton, L. L., Dooling, D. J., Ding, L., Mardis, E. R., Wilson, R. K., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E., Coope, R. J. N., & 323 othersDhalla, N., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Pleasance, E., Robertson, A. G., Schein, J. E., Shafiei, A., Sipahimalani, P., Slobodan, J. R., Stoll, D., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zeng, T., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Cherniack, A. D., Saksena, G., Onofrio, R. C., Pho, N. H., Carter, S. L., Schumacher, S. E., Tabak, B., Hernandez, B., Gentry, J., Nguyen, H., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Getz, G., Gabriel, S. B., Meyerson, M., Chin, L., Kucherlapati, R., Hoadley, K. A., Auman, J. T., Fan, C., Turman, Y. J., Shi, Y., Li, L., Topal, M. D., He, X., Chao, H. H., Prat, A., Silva, G. O., Iglesia, M. D., Zhao, W., Usary, J., Berg, J. S., Adams, M., Booker, J., Wu, J., Gulabani, A., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Mose, L. E., Jefferys, S. R., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Malik, S., Mahurkar, S., Shen, H., Weisenberger, D. J., Triche, T., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Berman, B. P., Van Den Berg, D. J., Baylin, S. B., Laird, P. W., Creighton, C. J., Donehower, L. A., Noble, M., Voet, D., Gehlenborg, N., Di Cara, D., Zhang, J., Zhang, H., Wu, C. J., Yingchun Liu, S., Lawrence, M. S., Zou, L., Sivachenko, A., Lin, P., Stojanov, P., Jing, R., Cho, J., Sinha, R., Park, R. W., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Park, P. J., Reynolds, S., Kreisberg, R. B., Bernard, B., Bressler, R., Erkkila, T., Lin, J., Thorsson, V., Zhang, W., Shmulevich, I., Ciriello, G., Weinhold, N., Schultz, N., Gao, J., Cerami, E., Gross, B., Jacobsen, A., Sinha, R., Aksoy, B. A., Antipin, Y., Reva, B., Shen, R., Taylor, B. S., Ladanyi, M., Sander, C., Anur, P., Spellman, P. T., Lu, Y., Liu, W., Verhaak, R. R. G., Mills, G. B., Akbani, R., Zhang, N., Broom, B. M., Casasent, T. D., Wakefield, C., Unruh, A. K., Baggerly, K., Coombes, K., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Zhu, J., Szeto, C. C., Scott, G. K., Yau, C., Paull, E. O., Carlin, D., Wong, C., Sokolov, A., Thusberg, J., Mooney, S., Ng, S., Goldstein, T. C., Ellrott, K., Grifford, M., Wilks, C., Ma, S., Craft, B., Yan, C., Hu, Y., Meerzaman, D., Gastier-Foster, J. M., Bowen, J., Ramirez, N. C., Black, A. D., Pyatt, R. E., White, P., Zmuda, E. J., Frick, J., Lichtenberg, T. M., Brookens, R., George, M. M., Gerken, M. A., Harper, H. A., Leraas, K. M., Wise, L. J., Tabler, T. R., McAllister, C., Barr, T., Hart-Kothari, M., Tarvin, K., Saller, C., Sandusky, G., Mitchell, C., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Dolzhansky, O., Abramov, M., Voronina, O., Potapova, O., Marks, J. R., Suchorska, W. M., Murawa, D., Kycler, W., Ibbs, M., Korski, K., Spychała, A., Murawa, P., Brzeziński, J. J., Perz, H., Łaźniak, R., Teresiak, M., Tatka, H., Leporowska, E., Bogusz-Czerniewicz, M., Malicki, J., Mackiewicz, A., Wiznerowicz, M., Van Le, X., Kohl, B., Viet Tien, N., Thorp, R., Van Bang, N., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Phuong, T. V. T., Thang, H. Q., Khan, K. Z., Penny, R., Mallery, D., Curley, E., Shelton, C., Yena, P., Ingle, J. N., Couch, F. J., Lingle, W. L., King, T. A., Gonzalez-Angulo, A. M., Dyer, M. D., Liu, S., Meng, X., Patangan, M., Waldman, F., Stöppler, H., Rathmell, W. K., Thorne, L., Huang, M., Boice, L., Hill, A., Morrison, C., Gaudioso, C., Bshara, W., Daily, K., Egea, S. C., Pegram, M. D., Gomez-Fernandez, C., Dhir, R., Bhargava, R., Brufsky, A., Shriver, C. D., Hooke, J. A., Campbell, J. L., Mural, R. J., Hu, H., Somiari, S., Larson, C., Deyarmin, B., Kvecher, L., Kovatich, A. J., Ellis, M. J., Stricker, T., White, K., Olopade, O., Luo, C., Chen, Y., Bose, R., Chang, L. W., Beck, A. H., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Wang, Z., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Shaw, K. R. M., Yang, L., Eley, G., Ferguson, M. L., Tarnuzzer, R. W., Zhang, J., Dillon, L. A. L., Buetow, K., Fielding, P., Ozenberger, B. A., Guyer, M. S., Sofia, H. J. & Palchik, J. D., Oct 4 2012, In: Nature. 490, 7418, p. 61-70 10 p.

      Research output: Contribution to journal › Article › peer-review

      8965 Scopus citations

    • LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-raf-ERK1/2-mTOR pathway in breast cancer patients

      Duong, M. L. T., Akli, S., Wei, C., Wingate, H. F., Liu, W., Lu, Y., Yi, M., Mills, G. B., Hunt, K. K. & Keyomarsi, K., Mar 2012, In: PLoS genetics. 8, 3, e1002538.

      Research output: Contribution to journal › Article › peer-review

      33 Scopus citations

    • Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma

      Davies, M. A., Fox, P. S., Papadopoulos, N. E., Bedikian, A. Y., Hwu, W-J., Lazar, A. J., Prieto, V. G., Culotta, K. S., Madden, T. L., Xu, Q., Huang, S., Deng, W., Ng, C. S., Gupta, S., Liu, W., Dancey, J. E., Wright, J. J., Bassett, R. L., Hwu, P. & Kim, K. B., Feb 15 2012, In: Clinical Cancer Research. 18, 4, p. 1120-1128 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      43 Scopus citations

    • Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1

      Byers, L. A., Wang, J., Nilsson, M. B., Fujimoto, J., Saintigny, P., Yordy, J., Giri, U., Peyton, M., Fan, Y. H., Diao, L., Masrorpour, F., Shen, L., Liu, W., Duchemann, B., Tumula, P., Bhardwaj, V., Welsh, J., Weber, S., Glisson, B. S., Kalhor, N., & 8 othersWistuba, I. I., Girard, L., Lippman, S. M., Mills, G. B., Coombes, K. R., Weinstein, J. N., Minna, J. D. & Heymach, J. V., Sep 2012, In: Cancer discovery. 2, 9, p. 798-811 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      408 Scopus citations

    • Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment

      Zeng, Z., Shi, Y. X., Tsao, T., Qiu, Y. H., Kornblau, S. M., Baggerly, K. A., Liu, W., Jessen, K., Liu, Y., Kantarjian, H., Rommel, C., Fruman, D. A., Andreeff, M. & Konopleva, M., Sep 27 2012, In: Blood. 120, 13, p. 2679-2689 11 p.

      Research output: Contribution to journal › Article › peer-review

      97 Scopus citations
    • 2013

      Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts

      Li, S., Shen, D., Shao, J., Crowder, R., Liu, W., Prat, A., He, X., Liu, S., Hoog, J., Lu, C., Ding, L., Griffith, O. L., Miller, C., Larson, D., Fulton, R. S., Harrison, M., Mooney, T., McMichael, J. F., Luo, J., Tao, Y., & 35 othersGoncalves, R., Schlosberg, C., Hiken, J. F., Saied, L., Sanchez, C., Giuntoli, T., Bumb, C., Cooper, C., Kitchens, R. T., Lin, A., Phommaly, C., Davies, S. R., Zhang, J., Kavuri, M. S., McEachern, D., Dong, Y. Y., Ma, C., Pluard, T., Naughton, M., Bose, R., Suresh, R., McDowell, R., Michel, L., Aft, R., Gillanders, W., DeSchryver, K., Wilson, R. K., Wang, S., Mills, G. B., Gonzalez-Angulo, A., Edwards, J. R., Maher, C., Perou, C. M., Mardis, E. R. & Ellis, M. J., Sep 26 2013, In: Cell Reports. 4, 6, p. 1116-1130 15 p.

      Research output: Contribution to journal › Article › peer-review

      495 Scopus citations

    • Identification and Characterization of MicroRNAs Controlled by the Osteoblast-Specific Transcription Factor Osterix

      Chen, Q., Liu, W., Sinha, K. M., Yasuda, H. & de Crombrugghe, B., Mar 5 2013, In: PloS one. 8, 3, e58104.

      Research output: Contribution to journal › Article › peer-review

      45 Scopus citations

    • The cancer genome atlas pan-cancer analysis project

      Weinstein, J. N., Collisson, E. A., Mills, G. B., Shaw, K. R. M., Ozenberger, B. A., Ellrott, K., Sander, C., Stuart, J. M., Chang, K., Creighton, C. J., Davis, C., Donehower, L., Drummond, J., Wheeler, D., Ally, A., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chu, A., Chuah, E., & 316 othersChun, H. J. E., Dhalla, N., Guin, R., Hirst, M., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Robertson, A. G., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Varhol, R. J., Beroukhim, R., Bhatt, A. S., Brooks, A. N., Cherniack, A. D., Freeman, S. S., Gabriel, S. B., Helman, E., Jung, J., Meyerson, M., Ojesina, A. I., Pedamallu, C. S., Saksena, G., Schumacher, S. E., Tabak, B., Zack, T., Lander, E. S., Bristow, C. A., Hadjipanayis, A., Haseley, P., Kucherlapati, R., Lee, S., Lee, E., Luquette, L. J., Mahadeshwar, H. S., Pantazi, A., Parfenov, M., Park, P. J., Protopopov, A., Ren, X., Santoso, N., Seidman, J., Seth, S., Song, X., Tang, J., Xi, R., Xu, A. W., Yang, L., Zeng, D., Auman, J. T., Balu, S., Buda, E., Fan, C., Hoadley, K. A., Jones, C. D., Meng, S., Mieczkowski, P. A., Parker, J. S., Perou, C. M., Roach, J., Shi, Y., Silva, G. O., Tan, D., Veluvolu, U., Waring, S., Wilkerson, M. D., Wu, J., Zhao, W., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jeffreys, S. R., Mose, L. E., Simons, J. V., Soloway, M. G., Baylin, S. B., Berman, B. P., Bootwalla, M. S., Danilova, L., Herman, J. G., Hinoue, T., Laird, P. W., Rhie, S. K., Shen, H., Triche, T., Weisenberger, D. J., Carter, S. L., Cibulskis, K., Chin, L., Zhang, J., Sougnez, C., Wang, M., Getz, G., Dinh, H., Doddapaneni, H. V., Gibbs, R., Gunaratne, P., Han, Y., Kalra, D., Kovar, C., Lewis, L., Morgan, M., Morton, D., Muzny, D., Reid, J., Xi, L., Cho, J., Dicara, D., Frazer, S., Gehlenborg, N., Heiman, D. I., Kim, J., Lawrence, M. S., Lin, P., Liu, Y., Noble, M. S., Stojanov, P., Voet, D., Zhang, H., Zou, L., Stewart, C., Bernard, B., Bressler, R., Eakin, A., Iype, L., Knijnenburg, T., Kramer, R., Kreisberg, R., Leinonen, K., Lin, J., Liu, Y., Miller, M., Reynolds, S. M., Rovira, H., Shmulevich, I., Thorsson, V., Yang, D., Zhang, W., Amin, S., Wu, C. J., Wu, C. C., Akbani, R., Aldape, K., Baggerly, K. A., Broom, B., Casasent, T. D., Cleland, J., Dodda, D., Edgerton, M., Han, L., Herbrich, S. M., Ju, Z., Kim, H., Lerner, S., Li, J., Liang, H., Liu, W., Lorenzi, P. L., Lu, Y., Melott, J., Nguyen, L., Su, X., Verhaak, R., Wang, W., Wong, A., Yang, Y., Yao, J., Yao, R., Yoshihara, K., Yuan, Y., Yung, A. K., Zhang, N., Zheng, S., Ryan, M., Kane, D. W., Aksoy, B. A., Ciriello, G., Dresdner, G., Gao, J., Gross, B., Jacobsen, A., Kahles, A., Ladanyi, M., Lee, W., Lehmann, K. V., Miller, M. L., Ramirez, R., Rätsch, G., Reva, B., Schultz, N., Senbabaoglu, Y., Shen, R., Sinha, R., Sumer, S. O., Sun, Y., Taylor, B. S., Weinhold, N., Fei, S., Spellman, P., Benz, C., Carlin, D., Cline, M., Craft, B., Goldman, M., Haussler, D., Ma, S., Ng, S., Paull, E., Radenbaugh, A., Salama, S., Sokolov, A., Swatloski, T., Uzunangelov, V., Waltman, P., Yau, C., Zhu, J., Hamilton, S. R., Abbott, S., Abbott, R., Dees, N. D., Delehaunty, K., Ding, L., Dooling, D. J., Eldred, J. M., Fronick, C. C., Fulton, R., Fulton, L. L., Kalicki-Veizer, J., Kanchi, K. L., Kandoth, C., Koboldt, D. C., Larson, D. E., Ley, T. J., Lin, L., Lu, C., Magrini, V. J., Mardis, E. R., McLellan, M. D., McMichael, J. F., Miller, C. A., O'Laughlin, M., Pohl, C., Schmidt, H., Smith, S. M., Walker, J., Wallis, J. W., Wendl, M. C., Wilson, R. K., Wylie, T., Zhang, Q., Burton, R., Jensen, M. A., Kahn, A., Pihl, T., Pot, D., Wan, Y., Levine, D. A., Black, A. D., Bowen, J., Frick, J., Gastier-Foster, J. M., Harper, H. A., Helsel, C., Leraas, K. M., Lichtenberg, T. M., McAllister, C., Ramirez, N. C., Sharpe, S., Wise, L., Zmuda, E., Chanock, S. J., Davidsen, T., Demchok, J. A., Eley, G., Felau, I., Sheth, M., Sofia, H., Staudt, L., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Omberg, L., Margolin, A., Raphael, B. J., Vandin, F., Wu, H. T., Leiserson, M. D. M., Benz, S. C., Vaske, C. J., Noushmehr, H., Wolf, D., Veer, L. V. T., Anastassiou, D., Yang, T. H. O., Lopez-Bigas, N., Gonzalez-Perez, A., Tamborero, D., Xia, Z., Li, W., Cho, D. Y., Przytycka, T., Hamilton, M., McGuire, S., Nelander, S., Johansson, P., Jörnsten, R. & Kling, T., Oct 1 2013, In: Nature Genetics. 45, 10, p. 1113-1120 8 p.

      Research output: Contribution to journal › Article › peer-review

      5099 Scopus citations

    • The somatic genomic landscape of glioblastoma

      TCGA Research Network, Oct 10 2013, In: Cell. 155, 2, p. 462 1 p.

      Research output: Contribution to journal › Article › peer-review

      3492 Scopus citations
    • 2014

      A comprehensive comparison of normalization methods for loading control and variance stabilization of reverse-phase protein array data

      Liu, W., Ju, Z., Lu, Y., Mills, G. B. & Akbani, R., Oct 16 2014, In: Cancer Informatics. 13, p. 109-117 9 p.

      Research output: Contribution to journal › Article › peer-review

      18 Scopus citations

    • A pan-cancer proteomic perspective on the cancer genome atlas

      Akbani, R., Ng, P. K. S., Werner, H. M. J., Shahmoradgoli, M., Zhang, F., Ju, Z., Liu, W., Yang, J. Y., Yoshihara, K., Li, J., Ling, S., Seviour, E. G., Ram, P. T., Minna, J. D., Diao, L., Tong, P., Heymach, J. V., Hill, S. M., Dondelinger, F., Städler, N., & 9 othersByers, L. A., Meric-Bernstam, F., Weinstein, J. N., Broom, B. M., Verhaak, R. G. W., Liang, H., Mukherjee, S., Lu, Y. & Mills, G. B., May 29 2014, In: Nature communications. 5, 3887.

      Research output: Contribution to journal › Article › peer-review

      406 Scopus citations

    • Comprehensive molecular characterization of gastric adenocarcinoma

      Cancer Genome Atlas Research Network, Sep 11 2014, In: Nature. 513, 7517, p. 202-209 8 p.

      Research output: Contribution to journal › Article › peer-review

      4565 Scopus citations

    • Comprehensive molecular characterization of urothelial bladder carcinoma

      Weinstein, J. N., Akbani, R., Broom, B. M., Wang, W., Verhaak, R. G. W., McConkey, D., Lerner, S., Morgan, M., Creighton, C. J., Smith, C., Cherniack, A. D., Kim, J., Pedamallu, C. S., Noble, M. S., Al-Ahmadie, H. A., Reuter, V. E., Rosenberg, J. E., F.Bajorin, D., Bochner, B. H., Solit, D. B., & 273 othersKoppie, T., Robinson, B., Gordenin, D. A., Fargo, D., Klimczak, L. J., Roberts, S. A., Au, J., Laird, P. W., Hinoue, T., Schultz, N., Ramirez, R., Hansel, D., Hoadley, K. A., Kim, W. Y., Damrauer, J. S., Baylin, S. B., Mungall, A. J., Robertson, A. G., Chu, A., Kwiatkowski, D. J., Sougnez, C., Cibulskis, K., Lichtenstein, L., Sivachenko, A., Stewart, C., Lawrence, M. S., Getz, G., Lander, E., Gabrie, S. B., Donehower, L., Carter, S. L., Saksena, G., Schumacher, S. E., Freeman, S. S., Jung, J., Bhatt, A. S., Pugh, T., Beroukhim, R., Meyerson, M., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Dhalla, N., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Wong, T., Wye, N., Bowlby, R., Chuah, E., Guin, R., Shen, H., Bootwalla, M. S., Triche, T., Lai, P. H., Van Den Berg, D. J., Weisenberger, D. J., Balu, S., Bodenheimer, T., Hoyle, A. P., Jefferys, S. R., Meng, S., Mose, L. E., Simons, J. V., Soloway, M. G., Wu, J., Parker, J. S., Hayes, D. N., Roach, J., Buda, E., Jones, C. D., Mieczkowski, P. A., Tan, D., Veluvolu, U., Waring, S., Auman, J. T., Perou, C. M., Wilkerson, M. D., Santoso, N., Parfenov, M., Ren, X., Pantazi, A., Hadjipanayis, A., Seidman, J., Kucherlapati, R., Lee, S., Yang, L., Park, P. J., Xu, A. W., Protopopov, A., Zhang, J., Bristow, C., Mahadeshwar, H. S., Seth, S., Song, X., Tang, J., Zeng, D., Chin, L., Guo, C., Casasent, T. D., Liu, W., Ju, Z., Motter, T., Peng, B., Ryan, M., Su, X., Yang, J. Y., Lorenzi, P. L., Yao, H., Zhang, N., Zhang, J., Mills, G. B., Cho, J., DiCara, D., Frazer, S., Gehlenborg, N., Heiman, D. I., Lin, P., Liu, Y., Stojanov, P., Voet, D., Zhang, H., Zou, L., Bernard, B., Kreisberg, D., Reynolds, S., Rovira, H., Shmulevich, I., Gao, J., Jacobsen, A., Aksoy, B. A., Antipin, Y., Ciriello, G., Dresdner, G., Gross, B., Lee, W., Reva, B., Shen, R., Sinha, R., Sumer, S. O., Weinhold, N., Ladanyi, M., Sander, C., Benz, C., Carlin, D., Haussler, D., Ng, S., Paull, E., Stuart, J., Zhu, J., Liu, Y., Zhang, W., Taylor, B. S., Lichtenberg, T. M., Zmuda, E., Barr, T., Black, A. D., George, M., Hanf, B., Helsel, C., McAllister, C., Ramirez, N. C., Tabler, T. R., Weaver, S., Wise, L., Bowen, J., Gastier-Foster, J. M., Jian, W., Tello, S., Ittman, M., Castro, P., McClenden, W. D., Gibbs, R., Saller, C., Tarvin, K., DiPiero, J. M., Owens, J., Bollag, R., Li, Q., Weinberger, P., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Swanson, P., Shelton, T., Curley, E., Gardner, J., Mallery, D., Penny, R., Van Bang, N., Hanh, P. T., Kohl, B., Van Le, X., Phu, B. D., Thorp, R., Tien, N. V., Vinh, L. Q., Sandusky, G., Burks, E., Christ, K., Gee, J., Holway, A., Moinzadeh, A., Sorcini, A., Sullivan, T., Garcia-Grossman, I. R., Regazzi, A. M., Boice, L., Rathmell, W. K., Thorne, L., Bastacky, S., Davies, B., Dhir, R., Gingrich, J., Hrebinko, R., Maranchie, J., Nelson, J., Parwani, A., Bshara, W., Gaudioso, C., Morrison, C., Alexopoulou, V., Bartlett, J., Engel, J., Kodeeswaran, S., Antic, T., O'Donnell, P. H., Smith, N. D., Steinberg, G. D., Egea, S., Gomez-Fernandez, C., Herbert, L., Jorda, M., Soloway, M., Beaver, A., Carter, S., Kapur, P., Lewis, C., Lotan, Y., Bondaruk, J., Czerniak, B., Skinner, E., Aldape, K., Jensen, M. A., Kahn, A. B., Pihl, T. D., Pot, D. A., Srinivasan, D., Wan, Y., Ferguson, M. L., Zenklusen, J. C., Davidsen, T., Demchok, J. A., Shaw, K. R. M., Sheth, M., Tarnuzzer, R., Wang, Z., Yang, L., Hutter, C., Ozenberger, B. A., Sofia, H. J. & Eley, G., 2014, In: Nature. 507, 7492, p. 315-322 8 p.

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      2314 Scopus citations

    • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

      Collisson, E. A., Campbell, J. D., Brooks, A. N., Berger, A. H., Lee, W., Chmielecki, J., Beer, D. G., Cope, L., Creighton, C. J., Danilova, L., Ding, L., Getz, G., Hammerman, P. S., Hayes, D. N., Hernandez, B., Herman, J. G., Heymach, J. V., Jurisica, I., Kucherlapati, R., Kwiatkowski, D., & 290 othersLadanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M. S., Travis, W. D., Weinstein, J. N., Wigle, D. A., Wilkerson, M. D., Chu, A., Cherniack, A. D., Hadjipanayis, A., Rosenberg, M., Weisenberger, D. J., Laird, P. W., Radenbaugh, A., Ma, S., Stuart, J. M., Byers, L. A., Baylin, S. B., Govindan, R., Meyerson, M., Gabriel, S. B., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E. S., Lawrence, M. S., Getz, E., Fulton, R., Fulton, L. L., McLellan, M. D., Wilson, R. K., Ye, K., Fronick, C. C., Maher, C. A., Miller, C. A., Wendl, M. C., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R., Robertson, A. G., Wye, N., Thiessen, N., Holt, R. A., Jones, S. J. M., Marra, M. A., Imielinski, M., Onofrio, R. C., Hodis, E., Zack, T., Helman, E., Pedamallu, C. S., Mesirov, J., Saksena, G., Schumacher, S. E., Carter, S. L., Garraway, L., Beroukhim, R., Lee, S., Mahadeshwar, H. S., Pantazi, A., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Yang, L., Zhang, J., Chen, P. C., Parfenov, M., Xu, A. W., Santoso, N., Chin, L., Park, P. J., Hoadley, K. A., Auman, J. T., Meng, S., Shi, Y., Buda, E., Waring, S., Veluvolu, U., Tan, D., Mieczkowski, P. A., Jones, C. D., Simons, J. V., Soloway, M. G., Bodenheimer, T., Jefferys, S. R., Roach, J., Hoyle, A. P., Wu, J., Balu, S., Singh, D., Prins, J. F., Marron, J. S., Parker, J. S., Perou, C. M., Liu, J., Maglinte, D. T., Lai, P. H., Bootwalla, M. S., Van Den Berg, D. J., Triche, T., Cho, J., DiCara, D., Heiman, D., Lin, P., Mallard, W., Voet, D., Zhang, H., Zou, L., Noble, M. S., Gehlenborg, N., Thorvaldsdottir, H., Nazaire, M. D., Robinson, J., Aksoy, B. A., Ciriello, G., Taylor, B. S., Dresdner, G., Gao, J., Gross, B., Seshan, V. E., Reva, B., Sumer, S. O., Weinhold, N., Sander, C., Ng, S., Zhu, J., Benz, C. C., Yau, C., Haussler, D., Spellman, P. T., Kimes, P. K., Broom, B. M., Wang, J., Lu, Y., Ng, P. K. S., Diao, L., Liu, W., Amos, C. I., Akbani, R., Mills, G. B., Curley, E., Paulauskis, J., Lau, K., Morris, S., Shelton, T., Mallery, D., Gardner, J., Penny, R., Saller, C., Tarvin, K., Richards, W. G., Cerfolio, R., Bryant, A., Raymond, D. P., Pennell, N. A., Farver, C., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Brown, J., Bauer, T., Dolzhanskiy, C. O., Potapova, O., Rotin, D., Voronina, O., Nemirovich-Danchenko, E., Fedosenko, K. V., Gal, A., Behera, M., Ramalingam, S. S., Sica, G., Flieder, D., Boyd, J., Weaver, J. E., Kohl, B., Thinh, D. H. Q., Sandusky, G., Juhl, H., Duhig, E., Illei, P., Gabrielson, E., Shin, J., Lee, B., Rogers, K., Trusty, D., Brock, M. V., Williamson, C., Burks, E., Rieger-Christ, K., Holway, A., Sullivan, T., Asiedu, M. K., Kosari, F., Rekhtman, N., Zakowski, M., Rusch, V. W., Zippile, P., Suh, J., Pass, H., Goparaju, C., Owusu-Sarpong, Y., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Sekhon, H., Albert, M., Eckman, J., Myers, J. B., Morrison, C., Gaudioso, C., Borgia, J. A., Bonomi, P., Pool, M., Liptay, M. J., Moiseenko, F., Zaytseva, I., Dienemann, H., Meister, M., Schnabel, P. A., Muley, T. R., Peifer, M., Gomez-Fernandez, C., Herbert, L., Egea, S., Huang, M., Thorne, L. B., Boice, L., Salazar, A. H., Funkhouser, W. K., Rathmell, W. K., Dhir, R., Yousem, S. A., Dacic, S., Schneider, F., Siegfried, J. M., Hajek, R., Watson, M. A., McDonald, S., Meyers, B., Clarke, B., Yang, I. A., Fong, K. M., Hunter, L., Windsor, M., Bowman, R. V., Peters, S., Letovanec, I., Khan, K. Z., Jensen, M. A., Snyder, E. E., Srinivasan, D., Kahn, A. B., Baboud, J., Pot, D. A., Shaw, K. R. M., Sheth, M., Davidsen, T., Demchok, J. A., Yang, L., Wang, Z., Tarnuzzer, R., Zenklusen, J. C., Ozenberger, B. A., Sofia, H. J. & Cheney, R., 2014, In: Nature. 511, 7511, p. 543-550 8 p.

      Research output: Contribution to journal › Article › peer-review

      3986 Scopus citations

    • Copy Number Gain of hsa-miR-569 at 3q26.2 Leads to Loss of TP53INP1 and Aggressiveness of Epithelial Cancers

      Chaluvally-Raghavan, P., Zhang, F., Pradeep, S., Hamilton, M. P., Zhao, X., Rupaimoole, R., Moss, T., Lu, Y., Yu, S., Pecot, C. V., Aure, M. R., Peuget, S., Rodriguez-Aguayo, C., Han, H. D., Zhang, D., Venkatanarayan, A., Krohn, M., Kristensen, V. N., Gagea, M., Ram, P., & 11 othersLiu, W., Lopez-Berestein, G., Lorenzi, P. L., Børresen-Dale, A. L., Chin, K., Gray, J., Dusetti, N. J., McGuire, S. E., Flores, E. R., Sood, A. K. & Mills, G. B., Dec 8 2014, In: Cancer cell. 26, 6, p. 863-879 17 p.

      Research output: Contribution to journal › Article › peer-review

      44 Scopus citations

    • Integrated Genomic Characterization of Papillary Thyroid Carcinoma

      Agrawal, N., Akbani, R., Aksoy, B. A., Ally, A., Arachchi, H., Asa, S. L., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Behera, M., Bernard, B., Beroukhim, R., Bishop, J. A., Black, A. D., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., & 223 othersBristow, C. A., Brookens, R., Brooks, D., Bryant, R., Buda, E., Butterfield, Y. S. N., Carling, T., Carlsen, R., Carter, S. L., Carty, S. E., Chan, T. A., Chen, A. Y., Cherniack, A. D., Cheung, D., Chin, L., Cho, J., Chu, A., Chuah, E., Cibulskis, K., Ciriello, G., Clarke, A., Clayman, G. L., Cope, L., Copland, J. A., Covington, K., Danilova, L., Davidsen, T., Demchok, J. A., DiCara, D., Dhalla, N., Dhir, R., Dookran, S. S., Dresdner, G., Eldridge, J., Eley, G., El-Naggar, A. K., Eng, S., Fagin, J. A., Fennell, T., Ferris, R. L., Fisher, S., Frazer, S., Frick, J., Gabriel, S. B., Ganly, I., Gao, J., Garraway, L. A., Gastier-Foster, J. M., Getz, G., Gehlenborg, N., Ghossein, R., Gibbs, R. A., Giordano, T. J., Gomez-Hernandez, K., Grimsby, J., Gross, B., Guin, R., Hadjipanayis, A., Harper, H. A., Hayes, D. N., Heiman, D. I., Herman, J. G., Hoadley, K. A., Hofree, M., Holt, R. A., Hoyle, A. P., Huang, F. W., Huang, M., Hutter, C. M., Ideker, T., Iype, L., Jacobsen, A., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kasaian, K., Kebebew, E., Khuri, F. R., Kim, J., Kramer, R., Kreisberg, R., Kucherlapati, R., Kwiatkowski, D. J., Ladanyi, M., Lai, P. H., Laird, P. W., Lander, E., Lawrence, M. S., Lee, D., Lee, E., Lee, S., Lee, W., Leraas, K. M., Lichtenberg, T. M., Lichtenstein, L., Lin, P., Ling, S., Liu, J., Liu, W., Liu, Y., LiVolsi, V. A., Lu, Y., Ma, Y., Mahadeshwar, H. S., Marra, M. A., Mayo, M., McFadden, D. G., Meng, S., Meyerson, M., Mieczkowski, P. A., Miller, M., Mills, G., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Nikiforov, Y. E., Noble, M. S., Ojesina, A. I., Owonikoko, T. K., Ozenberger, B. A., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Paull, E. O., Pedamallu, C. S., Perou, C. M., Prins, J. F., Protopopov, A., Ramalingam, S. S., Ramirez, N. C., Ramirez, R., Raphael, B. J., Rathmell, W. K., Ren, X., Reynolds, S. M., Rheinbay, E., Ringel, M. D., Rivera, M., Roach, J., Robertson, A. G., Rosenberg, M. W., Rosenthal, M., Sadeghi, S., Saksena, G., Sander, C., Santoso, N., Schein, J. E., Schultz, N., Schumacher, S. E., Seethala, R. R., Seidman, J., Senbabaoglu, Y., Seth, S., Sharpe, S., Shaw, K. R. M., Shen, J. P., Shen, R., Sherman, S., Sheth, M., Shi, Y., Shmulevich, I., Sica, G. L., Simons, J. V., Sinha, R., Sipahimalani, P., Smallridge, R. C., Sofia, H. J., Soloway, M. G., Song, X., Sougnez, C., Stewart, C., Stojanov, P., Stuart, J. M., Sumer, S. O., Sun, Y., Tabak, B., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorne, L., Thorsson, V., Tuttle, R. M., Umbricht, C. B., Van Den Berg, D. J., Vandin, F., Veluvolu, U., Verhaak, R. G. W., Vinco, M., Voet, D., Walter, V., Wang, Z., Waring, S., Weinberger, P. M., Weinhold, N., Weinstein, J. N., Weisenberger, D. J., Wheeler, D., Wilkerson, M. D., Wilson, J., Williams, M., Winer, D. A., Wise, L., Wu, J., Xi, L., Xu, A. W., Yang, L., Yang, L., Zack, T. I., Zeiger, M. A., Zeng, D., Zenklusen, J. C., Zhao, N., Zhang, H., Zhang, J., Zhang, J., Zhang, W., Zmuda, E. & Zou, L., Oct 23 2014, In: Cell. 159, 3, p. 676-690 15 p.

      Research output: Contribution to journal › Article › peer-review

      2157 Scopus citations

    • Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

      The Cancer Genome Atlas Research Network, Aug 14 2014, In: Cell. 158, 4, p. 929-944 16 p.

      Research output: Contribution to journal › Article › peer-review

      1093 Scopus citations

    • Phosphorylation of ETS1 by src family kinases prevents its recognition by the COP1 tumor suppressor

      Lu, G., Zhang, Q., Huang, Y., Song, J., Tomaino, R., Ehrenberger, T., Lim, E., Liu, W., Bronson, R. T., Bowden, M., Brock, J., Krop, I. E., Dillon, D. A., Gygi, S. P., Mills, G. B., Richardson, A. L., Signoretti, S., Yaffe, M. B. & Kaelin, W. G., Aug 11 2014, In: Cancer cell. 26, 2, p. 222-234 13 p.

      Research output: Contribution to journal › Article › peer-review

      60 Scopus citations

    • Preclinical and early clinical evaluation of the oral AKT inhibitor, MK-2206, for the treatment of acute myelogenous leukemia

      Konopleva, M. Y., Walter, R. B., Faderl, S. H., Jabbour, E. J., Zeng, Z., Borthakur, G., Huang, X., Kadia, T. M., Ruvolo, P. P., Feliu, J. B., Lu, H., Debose, L. K., Burger, J. A., Andreeff, M., Liu, W., Baggerly, K. A., Kornblau, S. M., Doyle, L. A., Estey, E. H. & Kantarjian, H. M., Apr 15 2014, In: Clinical Cancer Research. 20, 8, p. 2226-2235 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      66 Scopus citations

    • Spatial normalization of reverse phase protein array data

      Kaushik, P., Molinelli, E. J., Miller, M. L., Wang, W., Korkut, A., Liu, W., Ju, Z., Lu, Y., Mills, G. & Sander, C., Dec 12 2014, In: PloS one. 9, 12, e97213.

      Research output: Contribution to journal › Article › peer-review

      18 Scopus citations

    • Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer

      Liu, S., Meng, X., Chen, H., Liu, W., Miller, T., Murph, M., Lu, Y., Zhang, F., Gagea, M., Arteaga, C. L., Mills, G. B., Meric-Bernstam, F. & González-Angulo, A. M., 2014, In: Oncotarget. 5, 19, p. 9049-9064 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      23 Scopus citations
    • 2015

      A phase I/II study of the mTOR inhibitor everolimus in combination with hyperCVAD chemotherapy in patients with relapsed/refractory acute lymphoblastic leukemia

      Daver, N., Boumber, Y., Kantarjian, H., Ravandi, F., Cortes, J., Rytting, M. E., Kawedia, J. D., Basnett, J., Culotta, K. S., Zeng, Z., Lu, H., Richie, M. A., Garris, R., Xiao, L., Liu, W., Baggerly, K. A., Jabbour, E., O'Brien, S., Burger, J., Bendall, L. J., & 2 othersThomas, D. & Konopleva, M., Jun 15 2015, In: Clinical Cancer Research. 21, 12, p. 2704-2714 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      50 Scopus citations

    • Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

      Ince, T. A., Sousa, A. D., Jones, M. A., Harrell, J. C., Agoston, E. S., Krohn, M., Selfors, L. M., Liu, W., Chen, K., Yong, M., Buchwald, P., Wang, B., Hale, K. S., Cohick, E., Sergent, P., Witt, A., Kozhekbaeva, Z., Gao, S., Agoston, A. T., Merritt, M. A., & 5 othersFoster, R., Rueda, B. R., Crum, C. P., Brugge, J. S. & Mills, G. B., Jun 17 2015, In: Nature communications. 6, 7419.

      Research output: Contribution to journal › Article › peer-review

      137 Scopus citations

    • Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas

      Brat, D. J., Verhaak, R. G. W., Aldape, K. D., Yung, W. K. A., Salama, S. R., Cooper, L. A. D., Rheinbay, E., Miller, C. R., Vitucci, M., Morozova, O., Robertson, A. G., Noushmehr, H., Laird, P. W., Cherniack, A. D., Akbani, R., Huse, J. T., Ciriello, G., Poisson, L. M., Barnholtz-Sloan, J. S., Berger, M. S., & 287 othersBrennan, C., Colen, R. R., Colman, H., Flanders, A. E., Giannini, C., Grifford, M., Iavarone, A., Jain, R., Joseph, I., Kim, J., Kasaian, K., Mikkelsen, T., Murray, B. A., O'Neill, B. P., Pachter, L., Parsons, D. W., Sougnez, C., Sulman, E. P., Vandenberg, S. R., Van Meir, E. G., Von Deimling, A., Zhang, H., Crain, D., Lau, K., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, T., Sherman, M., Yena, P., Black, A., Bowen, J., Dicostanzo, K., Gastier-Foster, J., Leraas, K. M., Lichtenberg, T. M., Pierson, C. R., Ramirez, N. C., Taylor, C., Weaver, S., Wise, L., Zmuda, E., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M. L., Hutter, C. M., Shaw, K. R. M., Ozenberger, B. A., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Ayala, B., Baboud, J., Chudamani, S., Jensen, M. A., Liu, J., Pihl, T., Raman, R., Wan, Y., Wu, Y., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Beroukhim, R., Bootwalla, M. S., Bowlby, R., Bristow, C. A., Brooks, D., Butterfield, Y., Carlsen, R., Carter, S., Chin, L., Chu, A., Chuah, E., Cibulskis, K., Clarke, A., Coetzee, S. G., Dhalla, N., Fennell, T., Fisher, S., Gabriel, S., Getz, G., Gibbs, R., Guin, R., Hadjipanayis, A., Hayes, D. N., Hinoue, T., Hoadley, K., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S., Jones, C. D., Kucherlapati, R., Lai, P. H., Lander, E., Lee, S., Lichtenstein, L., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., Mayo, M., Meng, S., Meyerson, M. L., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Protopopov, A., Ren, X., Roach, J., Sabedot, T. S., Schein, J., Schumacher, S. E., Seidman, J. G., Seth, S., Shen, H., Simons, J. V., Sipahimalani, P., Soloway, M. G., Song, X., Sun, H., Tabak, B., Tam, A., Tan, D., Tang, J., Thiessen, N., Triche, T., Van Den Berg, D. J., Veluvolu, U., Waring, S., Weisenberger, D. J., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Xu, A. W., Yang, L., Zack, T. I., Zhang, J., Aksoy, B. A., Arachchi, H., Benz, C., Bernard, B., Carlin, D., Cho, J., DiCara, D., Frazer, S., Fuller, G. N., Gao, J. J., Gehlenborg, N., Haussler, D., Heiman, D. I., Iype, L., Jacobsen, A., Ju, Z., Katzman, S., Kim, H., Knijnenburg, T., Kreisberg, R. B., Lawrence, M. S., Lee, W., Leinonen, K., Lin, P., Ling, S., Liu, W., Liu, Y., Liu, Y., Lu, Y., Mills, G., Ng, S., Noble, M. S., Paull, E., Rao, A., Reynolds, S., Saksena, G., Sanborn, Z., Sander, C., Schultz, N., Senbabaoglu, Y., Shen, R., Shmulevich, I., Sinha, R., Stuart, J., Sumer, S. O., Sun, Y., Tasman, N., Taylor, B. S., Voet, D., Weinhold, N., Weinstein, J. N., Yang, D., Yoshihara, K., Zheng, S., Zhang, W., Zou, L., Abel, T., Sadeghi, S., Cohen, M. L., Eschbacher, J., Hattab, E. M., Raghunathan, A., Schniederjan, M. J., Aziz, D., Barnett, G., Barrett, W., Bigner, D. D., Boice, L., Brewer, C., Calatozzolo, C., Campos, B., Carlotti, C. G., Chan, T. A., Cuppini, L., Curley, E., Cuzzubbo, S., Devine, K., DiMeco, F., Duell, R., Elder, J. B., Fehrenbach, A., Finocchiaro, G., Friedman, W., Fulop, J., Gardner, J., Hermes, B., Herold-Mende, C., Jungk, C., Kendler, A., Lehman, N. L., Lipp, E., Liu, O., Mandt, R., McGraw, M., Mclendon, R., McPherson, C., Neder, L., Nguyen, P., Noss, A., Nunziata, R., Ostrom, Q. T., Palmer, C., Perin, A., Pollo, B., Potapov, A., Potapova, O., Rathmell, W. K., Rotin, D., Scarpace, L., Schilero, C., Senecal, K., Shimmel, K., Shurkhay, V., Sifri, S., Singh, R., Sloan, A. E., Smolenski, K., Staugaitis, S. M., Steele, R., Thorne, L., Tirapelli, D. P. C., Unterberg, A., Vallurupalli, M., Wang, Y., Warnick, R., Williams, F., Wolinsky, Y., Bell, S., Rosenberg, M., Stewart, C., Huang, F., Grimsby, J. L., Radenbaugh, A. J. & Zhang, J., Jun 25 2015, In: New England Journal of Medicine. 372, 26, p. 2481-2498 18 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2271 Scopus citations

    • Comprehensive genomic characterization of head and neck squamous cell carcinomas

      The Cancer Genome Atlas Network, Jan 29 2015, In: Nature. 517, 7536, p. 576-582 7 p.

      Research output: Contribution to journal › Article › peer-review

      2873 Scopus citations

    • Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

      Ciriello, G., Gatza, M. L., Beck, A. H., Wilkerson, M. D., Rhie, S. K., Pastore, A., Zhang, H., McLellan, M., Yau, C., Kandoth, C., Bowlby, R., Shen, H., Hayat, S., Fieldhouse, R., Lester, S. C., Tse, G. M. K., Factor, R. E., Collins, L. C., Allison, K. H., Chen, Y. Y., & 119 othersJensen, K., Johnson, N. B., Oesterreich, S., Mills, G. B., Cherniack, A. D., Robertson, G., Benz, C., Sander, C., Laird, P. W., Hoadley, K. A., King, T. A., Akbani, R., Auman, J. T., Balasundaram, M., Balu, S., Barr, T., Benz, S., Berrios, M., Beroukhim, R., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Brooks, D., Chin, L., Cho, J., Chudamani, S., Davidsen, T., Demchok, J. A., Dennison, J. B., Ding, L., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gao, J. J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gibson, W. J., Hayes, D. N., Heiman, D. I., Holbrook, A., Holt, R. A., Hoyle, A. P., Hu, H., Huang, M., Hutter, C. M., Hwang, E. S., Jefferys, S. R., Jones, S. J. M., Ju, Z., Kim, J., Lai, P. H., Lawrence, M. S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Ling, S., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Mardis, E., Marks, J., Marra, M. A., McAllister, C., Meng, S., Meyerson, M., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Olopade, O., Parker, J. S., Pihl, T., Saksena, G., Schumacher, S. E., Shaw, K. R. M., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Schein, J. E., Schultz, N., Sheth, M., Shi, Y., Shih, J., Shelley, C. S., Shriver, C., Simons, J. V., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tarnuzzer, R., Tiezzi, D. G., Van Den Berg, D. J., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wilson, R., Wise, L., Wiznerowicz, M., Wu, J., Wu, Y., Yang, L., Zack, T. I., Zenklusen, J. C., Zhang, J., Zmuda, E. & Perou, C. M., Oct 8 2015, In: Cell. 163, 2, p. 506-519 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1290 Scopus citations

    • Development of a robust classifier for quality control of reverse-phase protein arrays

      Ju, Z., Liu, W., Roebuck, P. L., Siwak, D. R., Zhang, N., Lu, Y., Davies, M. A., Akbani, R., Weinstein, J. N., Mills, G. B. & Coombes, K. R., Mar 15 2015, In: Bioinformatics. 31, 6, p. 912-918 7 p.

      Research output: Contribution to journal › Article › peer-review

      37 Scopus citations

    • Genomic Classification of Cutaneous Melanoma

      The Cancer Genome Atlas Network, Jun 20 2015, In: Cell. 161, 7, p. 1681-1696 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2235 Scopus citations

    • The Molecular Taxonomy of Primary Prostate Cancer

      Abeshouse, A., Ahn, J., Akbani, R., Ally, A., Amin, S., Andry, C. D., Annala, M., Aprikian, A., Armenia, J., Arora, A., Auman, J. T., Balasundaram, M., Balu, S., Barbieri, C. E., Bauer, T., Benz, C. C., Bergeron, A., Beroukhim, R., Berrios, M., Bivol, A., & 292 othersBodenheimer, T., Boice, L., Bootwalla, M. S., Borges Dos Reis, R., Boutros, P. C., Bowen, J., Bowlby, R., Boyd, J., Bradley, R. K., Breggia, A., Brimo, F., Bristow, C. A., Brooks, D., Broom, B. M., Bryce, A. H., Bubley, G., Burks, E., Butterfield, Y. S. N., Button, M., Canes, D., Carlotti, C. G., Carlsen, R., Carmel, M., Carroll, P. R., Carter, S. L., Cartun, R., Carver, B. S., Chan, J. M., Chang, M. T., Chen, Y., Cherniack, A. D., Chevalier, S., Chin, L., Cho, J., Chu, A., Chuah, E., Chudamani, S., Cibulskis, K., Ciriello, G., Clarke, A., Cooperberg, M. R., Corcoran, N. M., Costello, A. J., Cowan, J., Crain, D., Curley, E., David, K., Demchok, J. A., Demichelis, F., Dhalla, N., Dhir, R., Doueik, A., Drake, B., Dvinge, H., Dyakova, N., Felau, I., Ferguson, M. L., Frazer, S., Freedland, S., Fu, Y., Gabriel, S. B., Gao, J., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gerstein, M. B., Getz, G., Godwin, A. K., Gopalan, A., Graefen, M., Graim, K., Gribbin, T., Guin, R., Gupta, M., Hadjipanayis, A., Haider, S., Hamel, L., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Holbrook, A. H., Holt, R. A., Holway, A., Hovens, C. M., Hoyle, A. P., Huang, M., Hutter, C. M., Ittmann, M., Iype, L., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Juhl, H., Kahles, A., Kane, C. J., Kasaian, K., Kerger, M., Khurana, E., Kim, J., Klein, R. J., Kucherlapati, R., Lacombe, L., Ladanyi, M., Lai, P. H., Laird, P. W., Lander, E. S., Latour, M., Lawrence, M. S., Lau, K., Lebien, T., Lee, D., Lee, S., Lehmann, K. V., Leraas, K. M., Leshchiner, I., Leung, R., Libertino, J. A., Lichtenberg, T. M., Lin, P., Linehan, W. M., Ling, S., Lippman, S. M., Liu, J., Liu, W., Lochovsky, L., Loda, M., Logothetis, C., Lolla, L., Longacre, T., Lu, Y., Luo, J., Ma, Y., Mahadeshwar, H. S., Mallery, D., Mariamidze, A., Marra, M. A., Mayo, M., McCall, S., McKercher, G., Meng, S., Mes-Masson, A. M., Merino, M. J., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Shaw, K. R. M., Minner, S., Moinzadeh, A., Moore, R. A., Morris, S., Morrison, C., Mose, L. E., Mungall, A. J., Murray, B. A., Myers, J. B., Naresh, R., Nelson, J., Nelson, M. A., Nelson, P. S., Newton, Y., Noble, M. S., Noushmehr, H., Nykter, M., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Paulauskis, J., Penny, R., Perou, C. M., Piché, A., Pihl, T., Pinto, P. A., Prandi, D., Protopopov, A., Ramirez, N. C., Rao, A., Rathmell, W. K., Rätsch, G., Ren, X., Reuter, V. E., Reynolds, S. M., Rhie, S. K., Rieger-Christ, K., Roach, J., Robertson, A. G., Robinson, B., Rubin, M. A., Saad, F., Sadeghi, S., Saksena, G., Saller, C., Salner, A., Sanchez-Vega, F., Sander, C., Sandusky, G., Sauter, G., Sboner, A., Scardino, P. T., Scarlata, E., Schein, J. E., Schlomm, T., Schmidt, L. S., Schultz, N., Schumacher, S. E., Seidman, J., Neder, L., Seth, S., Sharp, A., Shelton, C., Shelton, T., Shen, H., Shen, R., Sherman, M., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simko, J., Simon, R., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Song, X., Sorcini, A., Sougnez, C., Stepa, S., Stewart, C., Stewart, J., Stuart, J. M., Sullivan, T. B., Sun, C., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Tarvin, K., Taylor, B. S., Teebagy, P., Tenggara, I., Têtu, B., Tewari, A., Thiessen, N., Thompson, T., Thorne, L. B., Tirapelli, D. P., Tomlins, S. A., Trevisan, F. A., Troncoso, P., True, L. D., Tsourlakis, M. C., Tyekucheva, S., Van Allen, E., Van Den Berg, D. J., Veluvolu, U., Verhaak, R., Vocke, C. D., Voet, D., Wan, Y., Wang, Q., Wang, W., Wang, Z., Weinhold, N., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Wise, L., Witte, J., Wu, C. C., Wu, J., Wu, Y., Xu, A. W., Yadav, S. S., Yang, L., Yang, L., Yau, C., Ye, H., Yena, P., Zeng, T., Zenklusen, J. C., Zhang, H., Zhang, J., Zhang, J., Zhang, W., Zhong, Y., Zhu, K. & Zmuda, E., Nov 5 2015, In: Cell. 163, 4, p. 1011-1025 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2130 Scopus citations
    • 2016

      Comprehensive pan-genomic characterization of adrenocortical carcinoma

      The Cancer Genome Atlas Research Network, May 9 2016, In: Cancer cell. 29, 5, p. 723-736 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      398 Scopus citations

    • Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer

      Chaluvally-Raghavan, P., Jeong, K. J., Pradeep, S., Silva, A. M., Yu, S., Liu, W., Moss, T., Rodriguez-Aguayo, C., Zhang, D., Ram, P., Liu, J., Lu, Y., Lopez-Berestein, G., Calin, G. A., Sood, A. K. & Mills, G. B., May 17 2016, In: Cell Reports. 15, 7, p. 1493-1504 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      76 Scopus citations

    • Down-regulation of the cyclin-dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis

      Guo, H., Jing, L., Cheng, Y., Atsaves, V., Lv, Y., Wu, T., Su, R., Zhang, Y., Zhang, R., Liu, W., Rassidakis, G. Z., Wei, Y., Nan, K. & Claret, F. X., Mar 1 2016, In: Hepatology. 63, 3, p. 898-913 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      41 Scopus citations

    • High intratumoral stromal content defines reactive breast cancer as a low-risk breast cancer subtype

      Dennison, J. B., Shahmoradgoli, M., Liu, W., Ju, Z., Meric-Bernstam, F., Perou, C. M., Sahin, A. A., Welm, A., Oesterreich, S., Sikora, M. J., Brown, R. E. & Mills, G. B., Oct 15 2016, In: Clinical Cancer Research. 22, 20, p. 5068-5078 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      27 Scopus citations
    • 2017

      Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

      Li, J., Zhao, W., Akbani, R., Liu, W., Ju, Z., Ling, S., Vellano, C. P., Roebuck, P., Yu, Q., Eterovic, A. K., Byers, L. A., Davies, M. A., Deng, W., Gopal, Y. N. V., Chen, G., von Euw, E. M., Slamon, D., Conklin, D., Heymach, J. V., Gazdar, A. F., & 5 othersMinna, J. D., Myers, J. N., Lu, Y., Mills, G. B. & Liang, H., Feb 13 2017, In: Cancer cell. 31, 2, p. 225-239 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      152 Scopus citations

    • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

      The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

      Research output: Contribution to journal › Article › peer-review

      Open Access
      624 Scopus citations

    • High-throughput profiling of signaling networks identifies mechanism-based combination therapy to eliminate microenvironmental resistance in acute myeloid leukemia

      Zeng, Z., Liu, W., Tsao, T., Qiu, Y. H., Zhao, Y., Samudio, I., Sarbassov, D. D., Kornblau, S. M., Baggerly, K. A., Kantarjian, H. M., Konopleva, M. & Andreeff, M., Aug 31 2017, In: Haematologica. 102, 9, p. 1537-1548 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • Integrated Molecular Characterization of Uterine Carcinosarcoma

      Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., & 130 othersBaylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In: Cancer cell. 31, 3, p. 411-423 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      273 Scopus citations

    • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

      Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L., & 150 othersChang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In: Cancer cell. 32, 2, p. 204-220.e15

      Research output: Contribution to journal › Article › peer-review

      Open Access
      563 Scopus citations

    • Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

      CONSORTIA, Mar 14 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      351 Scopus citations

    • The HGF/c-MET pathway is a driver and biomarker of VEGFR-inhibitor resistance and vascular remodeling in non–small cell lung cancer

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      Research output: Contribution to journal › Article › peer-review

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