Research output per year
Research output per year
- 25 results
Search results
-
2023
A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation
Ralvenius, W. T., Mungenast, A. E., Woolf, H., Huston, M. M., Gillingham, T. Z., Godin, S. K., Penney, J., Cam, H. P., Gao, F., Fernandez, C. G., Czako, B., Lightfoot, Y., Ray, W. J., Beckmann, A., Goate, A. M., Marcora, E., Romero-Molina, C., Ayata, P., Schaefer, A., Gjoneska, E., & 1 others, Nov 6 2023, In: Journal of Experimental Medicine. 220, 11, e20222105.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2020
Immunity to commensal skin fungi promotes psoriasiform skin inflammation
Hurabielle, C., Link, V. M., Bouladoux, N., Han, S. J., Merrill, E. D., Lightfoot, Y. L., Seto, N., Bleck, C. K. E., Smelkinson, M., Harrison, O. J., Linehan, J. L., Tamoutounour, S., Lionakis, M. S., Kaplan, M. J., Nakajima, S. & Belkaid, Y., Jul 14 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16465-16474 10 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Improved Mitochondrial Metabolism and Reduced Inflammation Following Attenuation of Murine Lupus With Coenzyme Q10 Analog Idebenone
Blanco, L. P., Pedersen, H. L., Wang, X., Lightfoot, Y. L., Seto, N., Carmona-Rivera, C., Yu, Z. X., Hoffmann, V., Yuen, P. S. T. & Kaplan, M. J., Mar 1 2020, In: Arthritis and Rheumatology. 72, 3, p. 454-464 11 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
2019
Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus
Rahman, S., Sagar, D., Hanna, R. N., Lightfoot, Y. L., Mistry, P., Smith, C. K., Manna, Z., Hasni, S., Siegel, R. M., Sanjuan, M. A., Kolbeck, R., Kaplan, M. J. & Casey, K. A., Jul 1 2019, In: Annals of the rheumatic diseases. 78, 7, p. 957-966 10 p.Research output: Contribution to journal › Article › peer-review
Open Access101 Scopus citations -
2018
Metabolic pathways and immunometabolism in rare kidney diseases
European Renal cDNA Bank cohort, Nephrotic Syndrome Study Network & Vasculitis Clinical Research Consortium, Aug 1 2018, In: Annals of the rheumatic diseases. 77, 8, p. 1227-1234 8 p.Research output: Contribution to journal › Article › peer-review
Open Access103 Scopus citations -
Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus
Liu, Y., Lightfoot, Y. L., Seto, N., Carmona-Rivera, C., Moore, E., Goel, R., O'Neil, L., Mistry, P., Hoffmann, V., Mondal, S., Premnath, P. N., Gribbons, K., Dell'Orso, S., Jiang, K., Thompson, P. R., Sun, H. W., Coonrod, S. A. & Kaplan, M. J., Dec 6 2018, In: JCI Insight. 3, 23Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
2017
Disentangling the role of neutrophil extracellular traps in rheumatic diseases
Lightfoot, Y. L. & Kaplan, M. J., 2017, In: Current opinion in rheumatology. 29, 1, p. 65-70 6 p.Research output: Contribution to journal › Review article › peer-review
20 Scopus citations -
Metabolic abnormalities and oxidative stress in lupus
Lightfoot, Y. L., Blanco, L. P. & Kaplan, M. J., Sep 1 2017, In: Current opinion in rheumatology. 29, 5, p. 442-449 8 p.Research output: Contribution to journal › Review article › peer-review
65 Scopus citations -
2015
Acute versus progressive onset of diabetes in NOD mice: Potential implications for therapeutic interventions in type 1 diabetes
Mathews, C. E., Xue, S., Posgai, A., Lightfoot, Y. L., Li, X., Lin, A., Wasserfall, C., Haller, M. J., Schatz, D. & Atkinson, M. A., Nov 2015, In: Diabetes. 64, 11, p. 3885-3890 6 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
SIGNR3-dependent immune regulation by Lactobacillus acidophilus surface layer protein A in colitis
Lightfoot, Y. L., Selle, K., Yang, T., Goh, Y. J., Sahay, B., Zadeh, M., Owen, J. L., Colliou, N., Li, E., Johannssen, T., Lepenies, B., Klaenhammer, T. R. & Mohamadzadeh, M., Apr 1 2015, In: EMBO Journal. 34, 7, p. 881-895 15 p.Research output: Contribution to journal › Article › peer-review
Open Access99 Scopus citations -
2014
Colonic immune suppression, barrier dysfunction, and dysbiosis by gastrointestinal bacillus anthracis infection
Lightfoot, Y. L., Yang, T., Sahay, B., Zadeh, M., Cheng, S. X., Wang, G. P., Owen, J. L. & Mohamadzadeh, M., Jun 19 2014, In: PloS one. 9, 6, e100532.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Epithelial CaSR deficiency alters intestinal integrity and promotes proinflammatory immune responses
Cheng, S. X., Lightfoot, Y. L., Yang, T., Zadeh, M., Tang, L., Sahay, B., Wang, G. P., Owen, J. L. & Mohamadzadeh, M., Nov 17 2014, In: FEBS Letters. 588, 22, p. 4158-4166 9 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
Impaired colonic B-cell responses by gastrointestinal Bacillus anthracis infection
Sahay, B., Owen, J. L., Zadeh, M., Yang, T., Lightfoot, Y. L., Abed, F. & Mohamadzadeh, M., Nov 1 2014, In: Journal of Infectious Diseases. 210, 9, p. 1499-1507 9 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2013
Activation of B cells by a dendritic cell-targeted oral vaccine
Sahay, B., Owen, J. L., Yang, T., Zadeh, M., Lightfoot, Y. L., Ge, J. W. & Mohamadzadeh, M., 2013, In: Current Pharmaceutical Biotechnology. 14, 10, p. 867-877 11 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Colonic Immune Stimulation by Targeted Oral Vaccine
Kathania, M., Zadeh, M., Lightfoot, Y. L., Roman, R. M., Sahay, B., Abbott, J. R. & Mohamadzadeh, M., Jan 30 2013, In: PloS one. 8, 1, e55143.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Microbiota impact on the epigenetic regulation of colorectal cancer
Yang, T., Owen, J. L., Lightfoot, Y. L., Kladde, M. P. & Mohamadzadeh, M., Dec 2013, In: Trends in Molecular Medicine. 19, 12, p. 714-725 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access78 Scopus citations -
Tailoring gut immune responses with lipoteichoic acid-deficient Lactobacillus acidophilus
Lightfoot, Y. L. & Mohamadzadeh, M., 2013, In: Frontiers in immunology. 4, FRB, Article 25.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Targeting aberrant colon cancer-specific DNA methylation with lipoteichoic acid-deficient Lactobacillus acidophilus
Lightfoot, Y. L., Yang, T., Sahay, B. & Mohamadzadeh, M., Jan 2013, In: Gut microbes. 4, 1Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2012
Immune-mediated β-cell death in type 1 diabetes: Lessons from human β-cell lines
Lightfoot, Y. L., Chen, J. & Mathews, C. E., Nov 2012, In: European Journal of Clinical Investigation. 42, 11, p. 1244-1251 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access21 Scopus citations -
Mitigating colon cancer with a novel strain of Lactobacillus acidophilus: A (re-)balancing act
Lightfoot, Y. L., Rehman, H. U., Myers, A. D. & Mohamadzadeh, M., Nov 2012, In: Immunotherapy. 4, 11, p. 1087-1089 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Oxidative stress and beta cell dysfunction
Lightfoot, Y. L., Chen, J. & Mathews, C. E., 2012, Autoimmunity: Methods and Protocols. Humana Press Inc., p. 347-362 16 p. (Methods in Molecular Biology; vol. 900).Research output: Chapter in Book/Report/Conference proceeding › Chapter
25 Scopus citations -
2011
Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes
Ize-Ludlow, D., Lightfoot, Y. L., Parker, M., Xue, S., Wasserfall, C., Haller, M. J., Schatz, D., Becker, D. J., Atkinson, M. A. & Mathews, C. E., Aug 2011, In: Diabetes. 60, 8, p. 2086-2091 6 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Role of the mitochondria in immune-mediated apoptotic death of the human pancreatic β cell line βLox5
Lightfoot, Y. L., Chen, J. & Mathews, C. E., 2011, In: PloS one. 6, 6, e20617.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2010
Attacking the source: Anti-PDX-1 responses in type 1 diabetes
Luzardo, Y. & Mathews, C. E., Jan 2010, In: Laboratory Investigation. 90, 1, p. 6-8 3 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
2007
Physiologic effects of forced down-regulation of dnaK and groEL expression in Streptococcus mutans
Lemos, J. A., Luzardo, Y. & Burne, R. A., Mar 2007, In: Journal of bacteriology. 189, 5, p. 1582-1588 7 p.Research output: Contribution to journal › Article › peer-review
Open Access84 Scopus citations