Yiling Lu

View Scopus Profile

Yiling Lu

Professor

 https://orcid.org/0000-0002-3662-2106
    Calculated based on number of publications stored in Pure and citations from Scopus
    1990 …2023

    Research activity per year

    Filter
    Article

    Search results

    • 2016

      Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

      Zhang, G., Frederick, D. T., Wu, L., Wei, Z., Krepler, C., Srinivasan, S., Chae, Y. C., Xu, X., Choi, H., Dimwamwa, E., Ope, O., Shannan, B., Basu, D., Zhang, D., Guha, M., Xiao, M., Randell, S., Sproesser, K., Xu, W., Liu, J., & 22 othersKarakousis, G. C., Schuchter, L. M., Gangadhar, T. C., Amaravadi, R. K., Gu, M., Xu, C., Ghosh, A., Xu, W., Tian, T., Zhang, J., Zha, S., Liu, Q., Brafford, P., Weeraratna, A., Davies, M. A., Wargo, J. A., Avadhani, N. G., Lu, Y., Mills, G. B., Altieri, D. C., Flaherty, K. T. & Herlyn, M., May 2 2016, In: Journal of Clinical Investigation. 126, 5, p. 1834-1856 23 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      202 Scopus citations

    • Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development

      Lisanti, S., Garlick, D. S., Bryant, K. G., Tavecchio, M., Mills, G. B., Lu, Y., Kossenkov, A. V., Showe, L. C., Languino, L. R. & Altieri, D. C., Nov 25 2016, In: Journal of Biological Chemistry. 291, 48, p. 25247-25254 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      30 Scopus citations

    • Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm

      Wang, C., Zhu, X., Feng, W., Yu, Y., Jeong, K., Guo, W., Lu, Y. & Mills, G. B., 2016, In: American Journal of Cancer Research. 6, 1, p. 27-37 11 p.

      Research output: Contribution to journal › Article › peer-review

      211 Scopus citations

    • YAP/TAZ regulates the insulin signaling via IRS1/2 in endometrial cancer

      Wang, C., Jeong, K., Jiang, H., Guo, W., Gu, C., Lu, Y. & Liang, J., 2016, In: American Journal of Cancer Research. 6, 5, p. 996-1010 15 p.

      Research output: Contribution to journal › Article › peer-review

      39 Scopus citations
    • 2017

      A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

      Krepler, C., Sproesser, K., Brafford, P., Beqiri, M., Garman, B., Xiao, M., Shannan, B., Watters, A., Perego, M., Zhang, G., Vultur, A., Yin, X., Liu, Q., Anastopoulos, I. N., Wubbenhorst, B., Wilson, M. A., Xu, W., Karakousis, G., Feldman, M., Xu, X., & 34 othersAmaravadi, R., Gangadhar, T. C., Elder, D. E., Haydu, L. E., Wargo, J. A., Davies, M. A., Lu, Y., Mills, G. B., Frederick, D. T., Barzily-Rokni, M., Flaherty, K. T., Hoon, D. S., Guarino, M., Bennett, J. J., Ryan, R. W., Petrelli, N. J., Shields, C. L., Terai, M., Sato, T., Aplin, A. E., Roesch, A., Darr, D., Angus, S., Kumar, R., Halilovic, E., Caponigro, G., Jeay, S., Wuerthner, J., Walter, A., Ocker, M., Boxer, M. B., Schuchter, L., Nathanson, K. L. & Herlyn, M., Nov 14 2017, In: Cell Reports. 21, 7, p. 1953-1967 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      104 Scopus citations

    • A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome

      Kelly, A. D., Kroeger, H., Yamazaki, J., Taby, R., Neumann, F., Yu, S., Lee, J. T., Patel, B., Li, Y., He, R., Liang, S., Lu, Y., Cesaroni, M., Pierce, S. A., Kornblau, S. M., Bueso-Ramos, C. E., Ravandi, F., Kantarjian, H. M., Jelinek, J. & Issa, J. P. J., Oct 1 2017, In: Leukemia. 31, 10, p. 2011-2019 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      32 Scopus citations

    • A murine preclinical syngeneic transplantation model for breast cancer precision medicine

      Federico, L., Chong, Z., Zhang, D., McGrail, D. J., Zhao, W., Jeong, K. J., Vellano, C. P., Ju, Z., Gagea, M., Liu, S., Mitra, S., Dennison, J. B., Lorenzi, P. L., Cardnell, R., Diao, L., Wang, J., Lu, Y., Byers, L. A., Perou, C. M., Lin, S. Y., & 1 othersMills, G. B., Apr 2017, In: Science Advances. 3, 4, e1600957.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations

    • A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers

      George, E., Kim, H., Krepler, C., Wenz, B., Makvandi, M., Tanyi, J. L., Brown, E., Zhang, R., Brafford, P., Jean, S., Mach, R. H., Lu, Y., Mills, G. B., Herlyn, M., Morgan, M., Zhang, X., Soslow, R., Drapkin, R., Johnson, N., Zheng, Y., & 3 othersCotsarelis, G., Nathanson, K. L. & Simpkins, F., Jan 12 2017, In: JCI Insight. 2, 1, e89760.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      50 Scopus citations

    • A unified approach to targeting the lysosome’s degradative and growth signaling roles

      Rebecca, V. W., Nicastri, M. C., McLaughlin, N., Fennelly, C., McAfee, Q., Ronghe, A., Nofal, M., Lim, C. Y., Witze, E., Chude, C. I., Zhang, G., Alicea, G. M., Piao, S., Murugan, S., Ojha, R., Levi, S. M., Wei, Z., Barber-Rotenberg, J. S., Murphy, M. E., Mills, G. B., & 12 othersLu, Y., Rabinowitz, J., Marmorstein, R., Liu, Q., Liu, S., Xu, X., Herlyn, M., Zoncu, R., Brady, D. C., Speicher, D. W., Winkler, J. D. & Amaravadi, R. K., Nov 2017, In: Cancer discovery. 7, 11, p. 1266-1283 18 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      146 Scopus citations

    • Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

      Li, J., Zhao, W., Akbani, R., Liu, W., Ju, Z., Ling, S., Vellano, C. P., Roebuck, P., Yu, Q., Eterovic, A. K., Byers, L. A., Davies, M. A., Deng, W., Gopal, Y. N. V., Chen, G., von Euw, E. M., Slamon, D., Conklin, D., Heymach, J. V., Gazdar, A. F., & 5 othersMinna, J. D., Myers, J. N., Lu, Y., Mills, G. B. & Liang, H., Feb 13 2017, In: Cancer cell. 31, 2, p. 225-239 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      153 Scopus citations

    • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

      The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

      Research output: Contribution to journal › Article › peer-review

      Open Access
      633 Scopus citations

    • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

      The Cancer Genome Atlas Research Network, Jun 15 2017, In: Cell. 169, 7, p. 1327-1341.e23

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1443 Scopus citations

    • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

      Robertson, A. G., Kim, J., Al-Ahmadie, H., Bellmunt, J., Guo, G., Cherniack, A. D., Hinoue, T., Laird, P. W., Hoadley, K. A., Akbani, R., Castro, M. A. A., Gibb, E. A., Kanchi, R. S., Gordenin, D. A., Shukla, S. A., Sanchez-Vega, F., Hansel, D. E., Czerniak, B. A., Reuter, V. E., Su, X., & 153 othersde Sa Carvalho, B., Chagas, V. S., Mungall, K. L., Sadeghi, S., Pedamallu, C. S., Lu, Y., Klimczak, L. J., Zhang, J., Choo, C., Ojesina, A. I., Bullman, S., Leraas, K. M., Lichtenberg, T. M., Wu, C. J., Schultz, N., Getz, G., Meyerson, M., Mills, G. B., McConkey, D. J., Albert, M., Alexopoulou, I., Ally, A., Antic, T., Aron, M., Balasundaram, M., Bartlett, J., Baylin, S. B., Beaver, A., Birol, I., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., Brooks, D., Broom, B. M., Bshara, W., Burks, E., Cárcano, F. M., Carlsen, R., Carvalho, A. L., Castle, E. P., Castro, P., Catto, J. W., Chesla, D. W., Chuah, E., Chudamani, S., Cortessis, V. K., Cottingham, S. L., Crain, D., Curley, E., Daneshmand, S., Demchok, J. A., Dhalla, N., Djaladat, H., Eckman, J., Egea, S. C., Engel, J., Felau, I., Ferguson, M. L., Gardner, J., Gastier-Foster, J. M., Gerken, M., Gomez-Fernandez, C. R., Harr, J., Hartmann, A., Herbert, L. M., Ho, T. H., Holt, R. A., Hutter, C. M., Jones, S. J. M., Jorda, M., Kahnoski, R. J., Kasaian, K., Kwiatkowski, D. J., Lai, P. H., Lane, B. R., Lerner, S. P., Liu, J., Lolla, L., Lotan, Y., Lucchesi, F. R., Ma, Y., Machado, R. D., Maglinte, D. T., Mallery, D., Marra, M. A., Martin, S. E., Mayo, M., Meraney, A., Moinzadeh, A., Moore, R. A., Mora Pinero, E. M., Morris, S., Morrison, C., Mungall, A. J., Myers, J. B., Naresh, R., O'Donnell, P. H., Parekh, D. J., Parfitt, J., Paulauskis, J. D., Sekhar Pedamallu, C., Penny, R. J., Pihl, T., Porten, S., Quintero-Aguilo, M. E., Ramirez, N. C., Rathmell, W. K., Rieger-Christ, K., Saller, C., Salner, A., Sandusky, G., Scapulatempo-Neto, C., Schein, J. E., Schuckman, A. K., Shelton, C., Shelton, T., Simko, J., Singh, P., Sipahimalani, P., Smith, N. D., Sofia, H. J., Sorcini, A., Stanton, M. L., Steinberg, G. D., Stoehr, R., Su, X., Sullivan, T., Sun, Q., Tam, A., Tarnuzzer, R., Tarvin, K., Taubert, H., Thiessen, N., Thorne, L., Tse, K., Tucker, K., Van Den Berg, D. J., van Kessel, K. E., Wach, S., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wise, L., Wong, T., Wu, Y., Yang, L., Zach, L. A., Zenklusen, J. C., Zhang, J., Zmuda, E. & Zwarthoff, E. C., Oct 19 2017, In: Cell. 171, 3, p. 540-556.e25

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1478 Scopus citations

    • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

      Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J., & 187 othersAsa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In: Cancer cell. 31, 2, p. 181-193 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      506 Scopus citations

    • Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

      Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In: Cell Systems. 4, 1, p. 73-83.e10

      Research output: Contribution to journal › Article › peer-review

      Open Access
      25 Scopus citations

    • Corilagin sensitizes epithelial ovarian cancer to chemotherapy by inhibiting Snail-glycolysis pathways

      Jia, L., Zho, J., Zhao, H., Yanjin, H., Lv, M., Zhao, N., Zheng, Z., Lu, Y., Ming, Y. & Yu, Y., Oct 2017, In: Oncology reports. 38, 4, p. 2464-2470 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      21 Scopus citations

    • Explore, visualize, and analyze functional cancer proteomic data using the cancer proteome atlas

      Li, J., Akbani, R., Zhao, W., Lu, Y., Weinstein, J. N., Mills, G. B. & Liang, H., Nov 1 2017, In: Cancer Research. 77, 21, p. e51-e54

      Research output: Contribution to journal › Article › peer-review

      Open Access
      75 Scopus citations

    • Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

      McGrail, D. J., Lin, C. C. J., Garnett, J., Liu, Q., Mo, W., Dai, H., Lu, Y., Yu, Q., Ju, Z., Yin, J., Vellano, C. P., Hennessy, B., Mills, G. B. & Lin, S. Y., Dec 1 2017, In: npj Systems Biology and Applications. 3, 1, 8.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      45 Scopus citations

    • Integrated genomic and molecular characterization of cervical cancer

      The Cancer Genome Atlas Research Network, Mar 16 2017, In: Nature. 543, 7645, p. 378-384 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      998 Scopus citations

    • Integrated genomic characterization of oesophageal carcinoma

      The Cancer Genome Atlas Research Network, Jan 12 2017, In: Nature. 541, 7636, p. 169-174 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1202 Scopus citations

    • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

      Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B., & 251 othersAkbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In: Cancer cell. 32, 2, p. 185-203.e13

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1185 Scopus citations

    • Integrated Molecular Characterization of Uterine Carcinosarcoma

      Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., & 130 othersBaylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R. G. W., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In: Cancer cell. 31, 3, p. 411-423 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      275 Scopus citations

    • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

      Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L., & 150 othersChang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R. G. W., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In: Cancer cell. 32, 2, p. 204-220.e15

      Research output: Contribution to journal › Article › peer-review

      Open Access
      569 Scopus citations

    • Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

      CONSORTIA, Mar 14 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      354 Scopus citations

    • Molecular heterogeneity at the network level: High-dimensional testing, clustering and a TCGA case study

      Städler, N., Dondelinger, F., Hill, S. M., Akbani, R., Lu, Y., Mills, G. B. & Mukherjee, S., Sep 15 2017, In: Bioinformatics. 33, 18, p. 2890-2896 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • Multiplatform-based molecular subtypes of non-small-cell lung cancer

      Chen, F., Zhang, Y., Parra, E., Rodriguez, J., Behrens, C., Akbani, R., Lu, Y., Kurie, J. M., Gibbons, D. L., Mills, G. B., Wistuba, I. I. & Creighton, C. J., Mar 1 2017, In: Oncogene. 36, 10, p. 1384-1393 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      94 Scopus citations

    • Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer

      Zhang, D., Zhang, G., Hu, X., Wu, L., Feng, Y., He, S., Zhang, Y., Hu, Z., Yang, L., Tian, T., Xu, W., Wei, Z., Lu, Y., Flaherty, K. T., Zhong, X., Mills, G. B., Gimotty, P. A., Xu, X., Herlyn, M. & Zhang, L., Jul 15 2017, In: Cancer Research. 77, 14, p. 3745-3757 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      26 Scopus citations

    • PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

      Lu, H., Liu, S., Zhang, G., Wu, B., Zhu, Y., Frederick, D. T., Hu, Y., Zhong, W., Randell, S., Sadek, N., Zhang, W., Chen, G., Cheng, C., Zeng, J., Wu, L. W., Zhang, J., Liu, X., Xu, W., Krepler, C., Sproesser, K., & 21 othersXiao, M., Miao, B., Liu, J., Song, C. D., Liu, J. Y., Karakousis, G. C., Schuchter, L. M., Lu, Y., Mills, G., Cong, Y., Chernoff, J., Guo, J., Boland, G. M., Sullivan, R. J., Wei, Z., Field, J., Amaravadi, R. K., Flaherty, K. T., Herlyn, M., Xu, X. & Guo, W., Oct 5 2017, In: Nature. 550, 7674, p. 133-136 4 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      128 Scopus citations

    • Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival

      Clarke, C. N., Lee, M. S., Wei, W., Manyam, G., Jiang, Z. Q., Lu, Y., Morris, J., Broom, B., Menter, D., Vilar-Sanchez, E., Raghav, K., Eng, C., Chang, G. J., Simon, I., Bernards, R., Overman, M., Mills, G. B., Maru, D. & Kopetz, S., Dec 1 2017, In: Annals of surgical oncology. 24, 13, p. 4051-4058 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      24 Scopus citations

    • Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers

      Sun, C., Fang, Y., Yin, J., Chen, J., Ju, Z., Zhang, D., Chen, X., Vellano, C. P., Jeong, K. J., Ng, P. K. S., Eterovic, A. K. B., Bhola, N. H., Lu, Y., Westin, S. N., Grandis, J. R., Lin, S. Y., Scott, K. L., Peng, G., Brugge, J. & Mills, G. B., May 31 2017, In: Science translational medicine. 9, 392, aal5148.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      160 Scopus citations

    • Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

      Wang, Y., Xu, X., Yu, S., Jeong, K. J., Zhou, Z., Han, L., Tsang, Y. H., Li, J., Chen, H., Mangala, L. S., Yuan, Y., Eterovic, A. K., Lu, Y., Sood, A. K., Scott, K. L., Mills, G. B. & Liang, H., Jul 2017, In: Genome research. 27, 7, p. 1112-1125 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      128 Scopus citations

    • YAP/TAZ-mediated upregulation of GAB2 leads to increased sensitivity to growth factor-induced activation of the PI3K pathway

      Wang, C., Gu, C., Jeong, K. J., Zhang, D., Guo, W., Lu, Y., Ju, Z., Panupinthu, N., Yang, J. Y., Gagea, M. M., Ng, P. K. S., Zhang, F. & Mills, G. B., 2017, In: Cancer Research. 77, 7, p. 1637-1648 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      42 Scopus citations
    • 2018

      A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

      The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer cell. 33, 4, p. 690-705.e9

      Research output: Contribution to journal › Article › peer-review

      Open Access
      379 Scopus citations

    • AKT isoform-specific expression and activation across cancer lineages

      Wang, J., Zhao, W., Guo, H., Fang, Y., Stockman, S. E., Bai, S., Ng, P. K. S., Li, Y., Yu, Q., Lu, Y., Jeong, K. J., Chen, X., Gao, M., Liang, J., Li, W., Tian, X., Jonasch, E., Mills, G. B. & Ding, Z., Jul 16 2018, In: BMC cancer. 18, 1, 742.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      30 Scopus citations

    • An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

      The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 400-416.e11

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1937 Scopus citations

    • A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

      The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 386-399.e12

      Research output: Contribution to journal › Article › peer-review

      Open Access
      186 Scopus citations

    • A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

      The Cancer Genome Atlas Research Network, Oct 24 2018, In: Cell Systems. 7, 4, p. 422-437.e7

      Research output: Contribution to journal › Article › peer-review

      Open Access
      120 Scopus citations

    • A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

      Peng, X., Xu, X., Wang, Y., Hawke, D. H., Yu, S., Han, L., Zhou, Z., Mojumdar, K., Jeong, K. J., Labrie, M., Tsang, Y. H., Zhang, M., Lu, Y., Hwu, P., Scott, K. L., Liang, H. & Mills, G. B., May 14 2018, In: Cancer cell. 33, 5, p. 817-828.e7

      Research output: Contribution to journal › Article › peer-review

      Open Access
      148 Scopus citations

    • BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

      Sun, C., Yin, J., Fang, Y., Chen, J., Jeong, K. J., Chen, X., Vellano, C. P., Ju, Z., Zhao, W., Zhang, D., Lu, Y., Meric-Bernstam, F., Yap, T. A., Hattersley, M., O'Connor, M. J., Chen, H., Fawell, S., Lin, S. Y., Peng, G. & Mills, G. B., Mar 12 2018, In: Cancer cell. 33, 3, p. 401-416.e8

      Research output: Contribution to journal › Article › peer-review

      Open Access
      198 Scopus citations

    • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

      The Cancer Genome Atlas Network, Apr 5 2018, In: Cell. 173, 2, p. 291-304.e6

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1391 Scopus citations

    • Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype

      Oh, S. C., Sohn, B. H., Cheong, J. H., Kim, S. B., Lee, J. E., Park, K. C., Lee, S. H., Park, J. L., Park, Y. Y., Lee, H. S., Jang, H. J., Park, E. S., Kim, S. C., Heo, J., Chu, I. S., Jang, Y. J., Mok, Y. J., Jung, W., Kim, B. H., Kim, A., & 18 othersCho, J. Y., Lim, J. Y., Hayashi, Y., Song, S., Elimova, E., Estralla, J. S., Lee, J. H., Bhutani, M. S., Lu, Y., Liu, W., Lee, J., Kang, W. K., Kim, S., Noh, S. H., Mills, G. B., Kim, S. Y., Ajani, J. A. & Lee, J. S., Dec 1 2018, In: Nature communications. 9, 1, 1777.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      219 Scopus citations

    • Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

      The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer cell. 33, 4, p. 721-735.e8

      Research output: Contribution to journal › Article › peer-review

      Open Access
      357 Scopus citations

    • Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

      The Cancer Genome Atlas Research Network, Aug 13 2018, In: Cancer cell. 34, 2, p. 211-224.e6

      Research output: Contribution to journal › Article › peer-review

      Open Access
      522 Scopus citations

    • Comprehensive Characterization of Cancer Driver Genes and Mutations

      The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 371-385.e18

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1228 Scopus citations

    • Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

      The Cancer Genome Atlas Research Network, Oct 30 2018, In: Cell Reports. 25, 5, p. 1304-1317.e5

      Research output: Contribution to journal › Article › peer-review

      Open Access
      273 Scopus citations

    • Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma

      Echevarría-Vargas, I. M., Reyes-Uribe, P. I., Guterres, A. N., Yin, X., Kossenkov, A. V., Liu, Q., Zhang, G., Krepler, C., Cheng, C., Wei, Z., Somasundaram, R., Karakousis, G., Xu, W., Morrissette, J. J. D., Lu, Y., Mills, G. B., Sullivan, R. J., Benchun, M., Frederick, D. T., Boland, G., & 9 othersFlaherty, K. T., Weeraratna, A. T., Herlyn, M., Amaravadi, R., Schuchter, L. M., Burd, C. E., Aplin, A. E., Xu, X. & Villanueva, J., May 2018, In: EMBO Molecular Medicine. 10, 5, e8446.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      66 Scopus citations

    • Distinct histone modifications denote early stress-induced drug tolerance in cancer

      Emran, A. A., Marzese, D. M., Menon, D. R., Stark, M. S., Torrano, J., Hammerlindl, H., Zhang, G., Brafford, P., Salomon, M. P., Nelson, N., Hammerlindl, S., Gupta, D., Mills, G. B., Lu, Y., Sturm, R. A., Flaherty, K., Dave, S. B. H., Gabrielli, B., Herlyn, M. & Schaider, H., 2018, In: Oncotarget. 9, 9, p. 8206-8222 17 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      55 Scopus citations

    • Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

      The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 227-238.e3

      Research output: Contribution to journal › Article › peer-review

      Open Access
      356 Scopus citations

    • Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

      Chen, G., Huang, A. C., Zhang, W., Zhang, G., Wu, M., Xu, W., Yu, Z., Yang, J., Wang, B., Sun, H., Xia, H., Man, Q., Zhong, W., Antelo, L. F., Wu, B., Xiong, X., Liu, X., Guan, L., Li, T., Liu, S., & 19 othersYang, R., Lu, Y., Dong, L., McGettigan, S., Somasundaram, R., Radhakrishnan, R., Mills, G., Lu, Y., Kim, J., Chen, Y. H., Dong, H., Zhao, Y., Karakousis, G. C., Mitchell, T. C., Schuchter, L. M., Herlyn, M., Wherry, E. J., Xu, X. & Guo, W., Aug 16 2018, In: Nature. 560, 7718, p. 382-386 5 p.

      Research output: Contribution to journal › Article › peer-review

      1777 Scopus citations

    • Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

      The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 194-212.e6

      Research output: Contribution to journal › Article › peer-review

      Open Access
      217 Scopus citations