Yiling Lu

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Yiling Lu

Professor

 https://orcid.org/0000-0002-3662-2106
    Calculated based on number of publications stored in Pure and citations from Scopus
    1990 …2023

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    • 2017

      A murine preclinical syngeneic transplantation model for breast cancer precision medicine

      Federico, L., Chong, Z., Zhang, D., McGrail, D. J., Zhao, W., Jeong, K. J., Vellano, C. P., Ju, Z., Gagea, M., Liu, S., Mitra, S., Dennison, J. B., Lorenzi, P. L., Cardnell, R., Diao, L., Wang, J., Lu, Y., Byers, L. A., Perou, C. M., Lin, S. Y., & 1 othersMills, G. B., Apr 2017, In: Science Advances. 3, 4, e1600957.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations

    • A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers

      George, E., Kim, H., Krepler, C., Wenz, B., Makvandi, M., Tanyi, J. L., Brown, E., Zhang, R., Brafford, P., Jean, S., Mach, R. H., Lu, Y., Mills, G. B., Herlyn, M., Morgan, M., Zhang, X., Soslow, R., Drapkin, R., Johnson, N., Zheng, Y., & 3 othersCotsarelis, G., Nathanson, K. L. & Simpkins, F., Jan 12 2017, In: JCI Insight. 2, 1, e89760.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      50 Scopus citations

    • A unified approach to targeting the lysosome’s degradative and growth signaling roles

      Rebecca, V. W., Nicastri, M. C., McLaughlin, N., Fennelly, C., McAfee, Q., Ronghe, A., Nofal, M., Lim, C. Y., Witze, E., Chude, C. I., Zhang, G., Alicea, G. M., Piao, S., Murugan, S., Ojha, R., Levi, S. M., Wei, Z., Barber-Rotenberg, J. S., Murphy, M. E., Mills, G. B., & 12 othersLu, Y., Rabinowitz, J., Marmorstein, R., Liu, Q., Liu, S., Xu, X., Herlyn, M., Zoncu, R., Brady, D. C., Speicher, D. W., Winkler, J. D. & Amaravadi, R. K., Nov 2017, In: Cancer discovery. 7, 11, p. 1266-1283 18 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      146 Scopus citations

    • Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

      Li, J., Zhao, W., Akbani, R., Liu, W., Ju, Z., Ling, S., Vellano, C. P., Roebuck, P., Yu, Q., Eterovic, A. K., Byers, L. A., Davies, M. A., Deng, W., Gopal, Y. N. V., Chen, G., von Euw, E. M., Slamon, D., Conklin, D., Heymach, J. V., Gazdar, A. F., & 5 othersMinna, J. D., Myers, J. N., Lu, Y., Mills, G. B. & Liang, H., Feb 13 2017, In: Cancer cell. 31, 2, p. 225-239 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      152 Scopus citations

    • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

      The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

      Research output: Contribution to journal › Article › peer-review

      Open Access
      624 Scopus citations

    • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

      The Cancer Genome Atlas Research Network, Jun 15 2017, In: Cell. 169, 7, p. 1327-1341.e23

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1430 Scopus citations

    • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

      Robertson, A. G., Kim, J., Al-Ahmadie, H., Bellmunt, J., Guo, G., Cherniack, A. D., Hinoue, T., Laird, P. W., Hoadley, K. A., Akbani, R., Castro, M. A. A., Gibb, E. A., Kanchi, R. S., Gordenin, D. A., Shukla, S. A., Sanchez-Vega, F., Hansel, D. E., Czerniak, B. A., Reuter, V. E., Su, X., & 153 othersde Sa Carvalho, B., Chagas, V. S., Mungall, K. L., Sadeghi, S., Pedamallu, C. S., Lu, Y., Klimczak, L. J., Zhang, J., Choo, C., Ojesina, A. I., Bullman, S., Leraas, K. M., Lichtenberg, T. M., Wu, C. J., Schultz, N., Getz, G., Meyerson, M., Mills, G. B., McConkey, D. J., Albert, M., Alexopoulou, I., Ally, A., Antic, T., Aron, M., Balasundaram, M., Bartlett, J., Baylin, S. B., Beaver, A., Birol, I., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., Brooks, D., Broom, B. M., Bshara, W., Burks, E., Cárcano, F. M., Carlsen, R., Carvalho, A. L., Castle, E. P., Castro, P., Catto, J. W., Chesla, D. W., Chuah, E., Chudamani, S., Cortessis, V. K., Cottingham, S. L., Crain, D., Curley, E., Daneshmand, S., Demchok, J. A., Dhalla, N., Djaladat, H., Eckman, J., Egea, S. C., Engel, J., Felau, I., Ferguson, M. L., Gardner, J., Gastier-Foster, J. M., Gerken, M., Gomez-Fernandez, C. R., Harr, J., Hartmann, A., Herbert, L. M., Ho, T. H., Holt, R. A., Hutter, C. M., Jones, S. J. M., Jorda, M., Kahnoski, R. J., Kasaian, K., Kwiatkowski, D. J., Lai, P. H., Lane, B. R., Lerner, S. P., Liu, J., Lolla, L., Lotan, Y., Lucchesi, F. R., Ma, Y., Machado, R. D., Maglinte, D. T., Mallery, D., Marra, M. A., Martin, S. E., Mayo, M., Meraney, A., Moinzadeh, A., Moore, R. A., Mora Pinero, E. M., Morris, S., Morrison, C., Mungall, A. J., Myers, J. B., Naresh, R., O'Donnell, P. H., Parekh, D. J., Parfitt, J., Paulauskis, J. D., Sekhar Pedamallu, C., Penny, R. J., Pihl, T., Porten, S., Quintero-Aguilo, M. E., Ramirez, N. C., Rathmell, W. K., Rieger-Christ, K., Saller, C., Salner, A., Sandusky, G., Scapulatempo-Neto, C., Schein, J. E., Schuckman, A. K., Shelton, C., Shelton, T., Simko, J., Singh, P., Sipahimalani, P., Smith, N. D., Sofia, H. J., Sorcini, A., Stanton, M. L., Steinberg, G. D., Stoehr, R., Su, X., Sullivan, T., Sun, Q., Tam, A., Tarnuzzer, R., Tarvin, K., Taubert, H., Thiessen, N., Thorne, L., Tse, K., Tucker, K., Van Den Berg, D. J., van Kessel, K. E., Wach, S., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wise, L., Wong, T., Wu, Y., Yang, L., Zach, L. A., Zenklusen, J. C., Zhang, J., Zmuda, E. & Zwarthoff, E. C., Oct 19 2017, In: Cell. 171, 3, p. 540-556.e25

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1467 Scopus citations

    • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

      Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J., & 187 othersAsa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In: Cancer cell. 31, 2, p. 181-193 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      500 Scopus citations

    • Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

      Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In: Cell Systems. 4, 1, p. 73-83.e10

      Research output: Contribution to journal › Article › peer-review

      Open Access
      25 Scopus citations

    • Corilagin sensitizes epithelial ovarian cancer to chemotherapy by inhibiting Snail-glycolysis pathways

      Jia, L., Zho, J., Zhao, H., Yanjin, H., Lv, M., Zhao, N., Zheng, Z., Lu, Y., Ming, Y. & Yu, Y., Oct 2017, In: Oncology reports. 38, 4, p. 2464-2470 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      21 Scopus citations

    • Explore, visualize, and analyze functional cancer proteomic data using the cancer proteome atlas

      Li, J., Akbani, R., Zhao, W., Lu, Y., Weinstein, J. N., Mills, G. B. & Liang, H., Nov 1 2017, In: Cancer Research. 77, 21, p. e51-e54

      Research output: Contribution to journal › Article › peer-review

      Open Access
      75 Scopus citations

    • Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

      McGrail, D. J., Lin, C. C. J., Garnett, J., Liu, Q., Mo, W., Dai, H., Lu, Y., Yu, Q., Ju, Z., Yin, J., Vellano, C. P., Hennessy, B., Mills, G. B. & Lin, S. Y., Dec 1 2017, In: npj Systems Biology and Applications. 3, 1, 8.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      45 Scopus citations

    • Integrated genomic and molecular characterization of cervical cancer

      The Cancer Genome Atlas Research Network, Mar 16 2017, In: Nature. 543, 7645, p. 378-384 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      985 Scopus citations

    • Integrated genomic characterization of oesophageal carcinoma

      The Cancer Genome Atlas Research Network, Jan 12 2017, In: Nature. 541, 7636, p. 169-174 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1195 Scopus citations

    • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

      Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B., & 251 othersAkbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In: Cancer cell. 32, 2, p. 185-203.e13

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1172 Scopus citations

    • Integrated Molecular Characterization of Uterine Carcinosarcoma

      Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., & 130 othersBaylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In: Cancer cell. 31, 3, p. 411-423 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      273 Scopus citations

    • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

      Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L., & 150 othersChang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In: Cancer cell. 32, 2, p. 204-220.e15

      Research output: Contribution to journal › Article › peer-review

      Open Access
      563 Scopus citations

    • Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

      CONSORTIA, Mar 14 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      351 Scopus citations

    • Molecular heterogeneity at the network level: High-dimensional testing, clustering and a TCGA case study

      Städler, N., Dondelinger, F., Hill, S. M., Akbani, R., Lu, Y., Mills, G. B. & Mukherjee, S., Sep 15 2017, In: Bioinformatics. 33, 18, p. 2890-2896 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • Multiplatform-based molecular subtypes of non-small-cell lung cancer

      Chen, F., Zhang, Y., Parra, E., Rodriguez, J., Behrens, C., Akbani, R., Lu, Y., Kurie, J. M., Gibbons, D. L., Mills, G. B., Wistuba, I. I. & Creighton, C. J., Mar 1 2017, In: Oncogene. 36, 10, p. 1384-1393 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      94 Scopus citations

    • Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer

      Zhang, D., Zhang, G., Hu, X., Wu, L., Feng, Y., He, S., Zhang, Y., Hu, Z., Yang, L., Tian, T., Xu, W., Wei, Z., Lu, Y., Flaherty, K. T., Zhong, X., Mills, G. B., Gimotty, P. A., Xu, X., Herlyn, M. & Zhang, L., Jul 15 2017, In: Cancer Research. 77, 14, p. 3745-3757 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      26 Scopus citations

    • PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

      Lu, H., Liu, S., Zhang, G., Wu, B., Zhu, Y., Frederick, D. T., Hu, Y., Zhong, W., Randell, S., Sadek, N., Zhang, W., Chen, G., Cheng, C., Zeng, J., Wu, L. W., Zhang, J., Liu, X., Xu, W., Krepler, C., Sproesser, K., & 21 othersXiao, M., Miao, B., Liu, J., Song, C. D., Liu, J. Y., Karakousis, G. C., Schuchter, L. M., Lu, Y., Mills, G., Cong, Y., Chernoff, J., Guo, J., Boland, G. M., Sullivan, R. J., Wei, Z., Field, J., Amaravadi, R. K., Flaherty, K. T., Herlyn, M., Xu, X. & Guo, W., Oct 5 2017, In: Nature. 550, 7674, p. 133-136 4 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      128 Scopus citations

    • Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival

      Clarke, C. N., Lee, M. S., Wei, W., Manyam, G., Jiang, Z. Q., Lu, Y., Morris, J., Broom, B., Menter, D., Vilar-Sanchez, E., Raghav, K., Eng, C., Chang, G. J., Simon, I., Bernards, R., Overman, M., Mills, G. B., Maru, D. & Kopetz, S., Dec 1 2017, In: Annals of surgical oncology. 24, 13, p. 4051-4058 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      23 Scopus citations

    • Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers

      Sun, C., Fang, Y., Yin, J., Chen, J., Ju, Z., Zhang, D., Chen, X., Vellano, C. P., Jeong, K. J., Ng, P. K. S., Eterovic, A. K. B., Bhola, N. H., Lu, Y., Westin, S. N., Grandis, J. R., Lin, S. Y., Scott, K. L., Peng, G., Brugge, J. & Mills, G. B., May 31 2017, In: Science translational medicine. 9, 392, aal5148.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      158 Scopus citations

    • Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

      Wang, Y., Xu, X., Yu, S., Jeong, K. J., Zhou, Z., Han, L., Tsang, Y. H., Li, J., Chen, H., Mangala, L. S., Yuan, Y., Eterovic, A. K., Lu, Y., Sood, A. K., Scott, K. L., Mills, G. B. & Liang, H., Jul 2017, In: Genome research. 27, 7, p. 1112-1125 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      128 Scopus citations

    • YAP/TAZ-mediated upregulation of GAB2 leads to increased sensitivity to growth factor-induced activation of the PI3K pathway

      Wang, C., Gu, C., Jeong, K. J., Zhang, D., Guo, W., Lu, Y., Ju, Z., Panupinthu, N., Yang, J. Y., Gagea, M. M., Ng, P. K. S., Zhang, F. & Mills, G. B., 2017, In: Cancer Research. 77, 7, p. 1637-1648 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      41 Scopus citations
    • 2016

      Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

      Linehan, W. M., Spellman, P. T., Ricketts, C. J., Creighton, C. J., Fei, S. S., Davis, C., Wheeler, D. A., Murray, B. A., Schmidt, L., Vocke, C. D., Peto, M., Al Mamun, A. A. M., Shinbrot, E., Sethi, A., Brooks, S., Rathmell, W. K., Brooks, A. N., Hoadley, K. A., Robertson, A. G., Brooks, D., & 208 othersBowlby, R., Sadeghi, S., Shen, H., Weisenberger, D. J., Bootwalla, M., Baylin, S. B., Laird, P. W., Cherniack, A. D., Saksena, G., Haake, S., Li, J., Liang, H., Lu, Y., Mills, G. B., Akbani, R., Leiserson, M. D. M., Raphael, B. J., Anur, P., Bottaro, D., Albiges, L., Barnabas, N., Choueiri, T. K., Czerniak, B., Godwin, A. K., Hakimi, A. A., Ho, T. H., Hsieh, J., Ittmann, M., Kim, W. Y., Krishnan, B., Merino, M. J., Shaw, K. R. M., Reuter, V. E., Reznik, E., Shelley, C. S., Shuch, B., Signoretti, S., Srinivasan, R., Tamboli, P., Thomas, G., Tickoo, S., Burnett, K., Crain, D., Gardner, J., Lau, K., Mallery, D., Morris, S., Paulauskis, J. D., Penny, R. J., Shelton, C., Shelton, W. T., Sherman, M., Thompson, E., Yena, P., Avedon, M. T., Bowen, J., Gastier-Foster, J. M., Gerken, M., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Santos, T., Wise, L., Zmuda, E., Demchok, J. A., Felau, I., Hutter, C. M., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Zhang, J., Ayala, B., Baboud, J., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Ally, A., Balasundaram, M., Balu, S., Beroukhim, R., Bodenheimer, T., Buhay, C., Butterfield, Y. S. N., Carlsen, R., Carter, S. L., Chao, H., Chuah, E., Clarke, A., Covington, K. R., Dahdouli, M., Dewal, N., Dhalla, N., Doddapaneni, H. V., Drummond, J. A., Gabriel, S. B., Gibbs, R. A., Guin, R., Hale, W., Hawes, A., Hayes, D. N., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kalra, D., Kovar, C., Lewis, L., Li, J., Ma, Y., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Morton, D., Mose, L. E., Mungall, A. J., Muzny, D., Parker, J. S., Perou, C. M., Roach, J., Schein, J. E., Schumacher, S. E., Shi, Y., Simons, J. V., Sipahimalani, P., Skelly, T., Soloway, M. G., Sougnez, C., Tam, A., Tan, D., Thiessen, N., Veluvolu, U., Wang, M., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Zhou, J., Bedford, J., Chen, F., Fu, Y., Gerstein, M., Haussler, D., Kasaian, K., Lai, P., Ling, S., Radenbaugh, A., Van Den Berg, D., Weinstein, J. N., Zhu, J., Albert, M., Alexopoulou, I., Andersen, J. J., Auman, J. T., Bartlett, J., Bastacky, S., Bergsten, J., Blute, M. L., Boice, L., Bollag, R. J., Boyd, J., Castle, E., Chen, Y. B., Cheville, J. C., Curley, E., Davies, B., DeVolk, A., Dhir, R., Dike, L., Eckman, J., Engel, J., Harr, J., Hrebinko, R., Huang, M., Huelsenbeck-Dill, L., Iacocca, M., Jacobs, B., Lobis, M., Maranchie, J. K., McMeekin, S., Myers, J., Nelson, J., Parfitt, J., Parwani, A., Petrelli, N., Rabeno, B., Roy, S., Salner, A. L., Slaton, J., Stanton, M., Thompson, R. H., Thorne, L., Tucker, K., Weinberger, P. M., Winemiller, C., Zach, L. A. & Zuna, R., Jan 14 2016, In: New England Journal of Medicine. 374, 2, p. 135-145 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      932 Scopus citations

    • Comprehensive pan-genomic characterization of adrenocortical carcinoma

      The Cancer Genome Atlas Research Network, May 9 2016, In: Cancer cell. 29, 5, p. 723-736 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      398 Scopus citations

    • Direct Upregulation of STAT3 by MicroRNA-551b-3p Deregulates Growth and Metastasis of Ovarian Cancer

      Chaluvally-Raghavan, P., Jeong, K. J., Pradeep, S., Silva, A. M., Yu, S., Liu, W., Moss, T., Rodriguez-Aguayo, C., Zhang, D., Ram, P., Liu, J., Lu, Y., Lopez-Berestein, G., Calin, G. A., Sood, A. K. & Mills, G. B., May 17 2016, In: Cell Reports. 15, 7, p. 1493-1504 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      76 Scopus citations

    • Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer

      Seviour, E. G., Sehgal, V., Lu, Y., Luo, Z., Moss, T., Zhang, F., Hill, S. M., Liu, W., Maiti, S. N., Cooper, L., Azencot, R., Lopez-Berestein, G., Rodriguez-Aguayo, C., Roopaimoole, R., Pecot, C., Sood, A. K., Mukherjee, S., Gray, J. W., Mills, G. B. & Ram, P. T., Feb 11 2016, In: Oncogene. 35, 6, p. 691-701 11 p.

      Research output: Contribution to journal › Article › peer-review

      37 Scopus citations

    • Glucose starvation induces mutation and lineage-dependent adaptive responses in a large collection of cancer cell lines

      He, N., Kim, N., Jeong, E., Lu, Y., Mills, G. B. & Yoon, S., Jan 2016, In: International journal of oncology. 48, 1, p. 67-72 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer

      Timsah, Z., Ahmed, Z., Ivan, C., Berrout, J., Gagea, M., Zhou, Y., Pena, G. N. A., Hu, X., Vallien, C., Kingsley, C. V., Lu, Y., Hancock, J. F., Liu, J., Gladden, A. B., Mills, G. B., Lopez-Berestein, G., Hung, M. C., Sood, A. K., Bogdanov, M. & Ladbury, J. E., Apr 28 2016, In: Oncogene. 35, 17, p. 2186-2196 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      23 Scopus citations

    • HSP70 inhibition limits FAK-dependent invasion and enhances the response to melanoma treatment with BRAF inhibitors

      Budina-Kolomets, A., Webster, M. R., Leu, J. I. J., Jennis, M., Krepler, C., Guerrini, A., Kossenkov, A. V., Xu, W., Karakousis, G., Schuchter, L., Amaravadi, R. K., Wu, H., Yin, X., Liu, Q., Lu, Y., Mills, G. B., Xu, X., George, D. L., Weeraratna, A. T. & Murphy, M. E., May 1 2016, In: Cancer Research. 76, 9, p. 2720-2730 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      30 Scopus citations

    • Integrative protein-based prognostic model for early-stage endometrioid endometrial cancer

      Yang, J. Y., Werner, H. M. J., Li, J., Westin, S. N., Lu, Y., Halle, M. K., Trovik, J., Salvesen, H. B., Mills, G. B. & Liang, H., Jan 15 2016, In: Clinical Cancer Research. 22, 2, p. 513-523 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      22 Scopus citations

    • MAPK activation predicts poor outcome and the MEK inhibitor, selumetinib, reverses antiestrogen resistance in ER-positive high-grade serous ovarian cancer

      Hew, K. E., Miller, P. C., El-Ashry, D., Sun, J., Besser, A. H., Ince, T. A., Gu, M., Wei, Z., Zhang, G., Brafford, P., Gao, W., Lu, Y., Mills, G. B., Slingerland, J. M. & Simpkins, F., Feb 15 2016, In: Clinical Cancer Research. 22, 4, p. 935-947 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      49 Scopus citations

    • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

      Ceccarelli, M., Barthel, F. P., Malta, T. M., Sabedot, T. S., Salama, S. R., Murray, B. A., Morozova, O., Newton, Y., Radenbaugh, A., Pagnotta, S. M., Anjum, S., Wang, J., Manyam, G., Zoppoli, P., Ling, S., Rao, A. A., Grifford, M., Cherniack, A. D., Zhang, H., Poisson, L., & 188 othersCarlotti, C. G., Tirapelli, D. P. D. C., Uppore Kukkillaya, A. R., Mikkelsen, T., Lau, C. C., Yung, W. K. A., Rabadan, R., Huse, J., Brat, D. J., Lehman, N. L., Barnholtz-Sloan, J. S., Zheng, S., Hess, K. R., Rao, G., Meyerson, M., Beroukhim, R., Cooper, L., Akbani, R., Wrensch, M., Haussler, D., Aldape, K. D., Laird, P. W., Gutmann, D. H., Noushmehr, H., Arachchi, H., Auman, J. T., Balasundaram, M., Balu, S., Barnett, G., Baylin, S., Bell, S., Benz, C., Bir, N., Black, K. L., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Bristow, C. A., Butterfield, Y. S. N., Chen, Q. R., Chin, L., Cho, J., Chuah, E., Chudamani, S., Coetzee, S. G., Cohen, M. L., Colman, H., Couce, M., D'Angelo, F., Davidsen, T., Davis, A., Demchok, J. A., Devine, K., Ding, L., Duell, R., Elder, J. B., Eschbacher, J. M., Fehrenbach, A., Ferguson, M., Frazer, S., Fuller, G., Fulop, J., Gabriel, S. B., Garofano, L., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Giannini, C., Gibson, W. J., Hadjipanayis, A., Hayes, D. N., Heiman, D. I., Hermes, B., Hilty, J., Hoadley, K. A., Hoyle, A. P., Huang, M., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Ju, Z., Kastl, A., Kendler, A., Kim, J., Kucherlapati, R., Lai, P. H., Lawrence, M. S., Lee, S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Liu, Y., Liu, J., Ljubimova, J. Y., Lu, Y., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., McGraw, M., McPherson, C., Meng, S., Mieczkowski, P. A., Miller, C. R., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Naresh, R., Naska, T., Neder, L., Noble, M. S., Noss, A., O'Neill, B. P., Ostrom, Q. T., Palmer, C., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pierson, C. R., Pihl, T., Protopopov, A., Radenbaugh, A., Ramirez, N. C., Rathmell, W. K., Ren, X., Roach, J., Robertson, A. G., Saksena, G., Schein, J. E., Schumacher, S. E., Seidman, J., Senecal, K., Seth, S., Shen, H., Shi, Y., Shih, J., Shimmel, K., Sicotte, H., Sifri, S., Silva, T., Simons, J. V., Singh, R., Skelly, T., Sloan, A. E., Sofia, H. J., Soloway, M. G., Song, X., Sougnez, C., Souza, C., Staugaitis, S. M., Sun, H., Sun, C., Tan, D., Tang, J., Tang, Y., Thorne, L., Trevisan, F. A., Triche, T., Van Den Berg, D. J., Veluvolu, U., Voet, D., Wan, Y., Wang, Z., Warnick, R., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Williams, F., Wise, L., Wolinsky, Y., Wu, J., Xu, A. W., Yang, L., Yang, L., Zack, T. I., Zenklusen, J. C., Zhang, J., Zhang, W., Zhang, J., Zmuda, E., Noushmehr, H., Iavarone, A. & Verhaak, R., Jan 28 2016, In: Cell. 164, 3, p. 550-563 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1446 Scopus citations

    • Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma

      Chen, F., Zhang, Y., Şenbabaoğlu, Y., Ciriello, G., Yang, L., Reznik, E., Shuch, B., Micevic, G., De Velasco, G., Shinbrot, E., Noble, M. S., Lu, Y., Covington, K. R., Xi, L., Drummond, J. A., Muzny, D., Kang, H., Lee, J., Tamboli, P., Reuter, V., & 20 othersShelley, C. S., Kaipparettu, B. A., Bottaro, D. P., Godwin, A. K., Gibbs, R. A., Getz, G., Kucherlapati, R., Park, P. J., Sander, C., Henske, E. P., Zhou, J. H., Kwiatkowski, D. J., Ho, T. H., Choueiri, T. K., Hsieh, J. J., Akbani, R., Mills, G. B., Hakimi, A. A., Wheeler, D. A. & Creighton, C. J., Mar 15 2016, In: Cell Reports. 14, 10, p. 2476-2489 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      264 Scopus citations

    • Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer

      Bissig-Choisat, B., Kettlun-Leyton, C., Legras, X. D., Zorman, B., Barzi, M., Chen, L. L., Amin, M. D., Huang, Y. H., Pautler, R. G., Hampton, O. A., Prakash, M. M., Yang, D., Borowiak, M., Muzny, D., Doddapaneni, H. V., Hu, J., Shi, Y., Gaber, M. W., Hicks, M. J., Thompson, P. A., & 9 othersLu, Y., Mills, G. B., Finegold, M., Goss, J. A., Parsons, D. W., Vasudevan, S. A., Sumazin, P., López-Terrada, D. & Bissig, K. D., Aug 1 2016, In: Journal of Hepatology. 65, 2, p. 325-333 9 p.

      Research output: Contribution to journal › Article › peer-review

      56 Scopus citations

    • Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

      Jeong, A. L., Han, S., Lee, S., Su Park, J., Lu, Y., Yu, S., Li, J., Chun, K. H., Mills, G. B. & Yang, Y., Jun 7 2016, In: Scientific reports. 6, 27391.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      25 Scopus citations

    • Personalized preclinical trials in BRAF Inhibitor-resistant patient-derived xenograft models identify second-line combination therapies

      Krepler, C., Xiao, M., Sproesser, K., Brafford, P. A., Shannan, B., Beqiri, M., Liu, Q., Xu, W., Garman, B., Nathanson, K. L., Xu, X., Karakousis, G. C., Mills, G. B., Lu, Y., Ahmed, T. A., Poulikakos, P. I., Caponigro, G., Boehm, M., Peters, M., Schuchter, L. M., & 2 othersTweeraratna, A. & Herlyn, M., Apr 1 2016, In: Clinical Cancer Research. 22, 7, p. 1592-1602 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      109 Scopus citations

    • Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

      Zhang, G., Frederick, D. T., Wu, L., Wei, Z., Krepler, C., Srinivasan, S., Chae, Y. C., Xu, X., Choi, H., Dimwamwa, E., Ope, O., Shannan, B., Basu, D., Zhang, D., Guha, M., Xiao, M., Randell, S., Sproesser, K., Xu, W., Liu, J., & 22 othersKarakousis, G. C., Schuchter, L. M., Gangadhar, T. C., Amaravadi, R. K., Gu, M., Xu, C., Ghosh, A., Xu, W., Tian, T., Zhang, J., Zha, S., Liu, Q., Brafford, P., Weeraratna, A., Davies, M. A., Wargo, J. A., Avadhani, N. G., Lu, Y., Mills, G. B., Altieri, D. C., Flaherty, K. T. & Herlyn, M., May 2 2016, In: Journal of Clinical Investigation. 126, 5, p. 1834-1856 23 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      200 Scopus citations

    • Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development

      Lisanti, S., Garlick, D. S., Bryant, K. G., Tavecchio, M., Mills, G. B., Lu, Y., Kossenkov, A. V., Showe, L. C., Languino, L. R. & Altieri, D. C., Nov 25 2016, In: Journal of Biological Chemistry. 291, 48, p. 25247-25254 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      30 Scopus citations

    • Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm

      Wang, C., Zhu, X., Feng, W., Yu, Y., Jeong, K., Guo, W., Lu, Y. & Mills, G. B., 2016, In: American Journal of Cancer Research. 6, 1, p. 27-37 11 p.

      Research output: Contribution to journal › Article › peer-review

      207 Scopus citations

    • YAP/TAZ regulates the insulin signaling via IRS1/2 in endometrial cancer

      Wang, C., Jeong, K., Jiang, H., Guo, W., Gu, C., Lu, Y. & Liang, J., 2016, In: American Journal of Cancer Research. 6, 5, p. 996-1010 15 p.

      Research output: Contribution to journal › Article › peer-review

      39 Scopus citations
    • 2015

      Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas

      Brat, D. J., Verhaak, R., Aldape, K. D., Yung, W. K. A., Salama, S. R., Cooper, L. A. D., Rheinbay, E., Miller, C. R., Vitucci, M., Morozova, O., Robertson, A. G., Noushmehr, H., Laird, P. W., Cherniack, A. D., Akbani, R., Huse, J. T., Ciriello, G., Poisson, L. M., Barnholtz-Sloan, J. S., Berger, M. S., & 287 othersBrennan, C., Colen, R., Colman, H., Flanders, A. E., Giannini, C., Grifford, M., Iavarone, A., Jain, R., Joseph, I., Kim, J., Kasaian, K., Mikkelsen, T., Murray, B. A., O'Neill, B. P., Pachter, L., Parsons, D. W., Sougnez, C., Sulman, E. P., Vandenberg, S. R., Van Meir, E. G., Von Deimling, A., Zhang, H., Crain, D., Lau, K., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, T., Sherman, M., Yena, P., Black, A., Bowen, J., Dicostanzo, K., Gastier-Foster, J., Leraas, K. M., Lichtenberg, T. M., Pierson, C. R., Ramirez, N. C., Taylor, C., Weaver, S., Wise, L., Zmuda, E., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M. L., Hutter, C. M., Shaw, K. R. M., Ozenberger, B. A., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Ayala, B., Baboud, J., Chudamani, S., Jensen, M. A., Liu, J., Pihl, T., Raman, R., Wan, Y., Wu, Y., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Beroukhim, R., Bootwalla, M. S., Bowlby, R., Bristow, C. A., Brooks, D., Butterfield, Y., Carlsen, R., Carter, S., Chin, L., Chu, A., Chuah, E., Cibulskis, K., Clarke, A., Coetzee, S. G., Dhalla, N., Fennell, T., Fisher, S., Gabriel, S., Getz, G., Gibbs, R., Guin, R., Hadjipanayis, A., Hayes, D. N., Hinoue, T., Hoadley, K., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S., Jones, C. D., Kucherlapati, R., Lai, P. H., Lander, E., Lee, S., Lichtenstein, L., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., Mayo, M., Meng, S., Meyerson, M. L., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Protopopov, A., Ren, X., Roach, J., Sabedot, T. S., Schein, J., Schumacher, S. E., Seidman, J. G., Seth, S., Shen, H., Simons, J. V., Sipahimalani, P., Soloway, M. G., Song, X., Sun, H., Tabak, B., Tam, A., Tan, D., Tang, J., Thiessen, N., Triche, T., Van Den Berg, D. J., Veluvolu, U., Waring, S., Weisenberger, D. J., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Xu, A. W., Yang, L., Zack, T. I., Zhang, J., Aksoy, B. A., Arachchi, H., Benz, C., Bernard, B., Carlin, D., Cho, J., DiCara, D., Frazer, S., Fuller, G. N., Gao, J. J., Gehlenborg, N., Haussler, D., Heiman, D. I., Iype, L., Jacobsen, A., Ju, Z., Katzman, S., Kim, H., Knijnenburg, T., Kreisberg, R. B., Lawrence, M. S., Lee, W., Leinonen, K., Lin, P., Ling, S., Liu, W., Liu, Y., Liu, Y., Lu, Y., Mills, G. B., Ng, S., Noble, M. S., Paull, E., Rao, A., Reynolds, S., Saksena, G., Sanborn, Z., Sander, C., Schultz, N., Senbabaoglu, Y., Shen, R., Shmulevich, I., Sinha, R., Stuart, J., Sumer, S. O., Sun, Y., Tasman, N., Taylor, B. S., Voet, D., Weinhold, N., Weinstein, J. N., Yang, D., Yoshihara, K., Zheng, S., Zhang, W., Zou, L., Abel, T., Sadeghi, S., Cohen, M. L., Eschbacher, J., Hattab, E. M., Raghunathan, A., Schniederjan, M. J., Aziz, D., Barnett, G., Barrett, W., Bigner, D. D., Boice, L., Brewer, C., Calatozzolo, C., Campos, B., Carlotti, C. G., Chan, T. A., Cuppini, L., Curley, E., Cuzzubbo, S., Devine, K., DiMeco, F., Duell, R., Elder, J. B., Fehrenbach, A., Finocchiaro, G., Friedman, W., Fulop, J., Gardner, J., Hermes, B., Herold-Mende, C., Jungk, C., Kendler, A., Lehman, N. L., Lipp, E., Liu, O., Mandt, R., McGraw, M., Mclendon, R., McPherson, C., Neder, L., Nguyen, P., Noss, A., Nunziata, R., Ostrom, Q. T., Palmer, C., Perin, A., Pollo, B., Potapov, A., Potapova, O., Rathmell, W. K., Rotin, D., Scarpace, L., Schilero, C., Senecal, K., Shimmel, K., Shurkhay, V., Sifri, S., Singh, R., Sloan, A. E., Smolenski, K., Staugaitis, S. M., Steele, R., Thorne, L., Tirapelli, D. P. C., Unterberg, A., Vallurupalli, M., Wang, Y., Warnick, R., Williams, F., Wolinsky, Y., Bell, S., Rosenberg, M., Stewart, C., Huang, F., Grimsby, J. L., Radenbaugh, A. J. & Zhang, J., Jun 25 2015, In: New England Journal of Medicine. 372, 26, p. 2481-2498 18 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2271 Scopus citations

    • Comprehensive genomic characterization of head and neck squamous cell carcinomas

      The Cancer Genome Atlas Network, Jan 29 2015, In: Nature. 517, 7536, p. 576-582 7 p.

      Research output: Contribution to journal › Article › peer-review

      2873 Scopus citations

    • Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers

      Yan, X., Hu, Z., Feng, Y., Hu, X., Yuan, J., Zhao, S. D., Zhang, Y., Yang, L., Shan, W., He, Q., Fan, L., Kandalaft, L. E., Tanyi, J. L., Li, C., Yuan, C. X., Zhang, D., Yuan, H., Hua, K., Lu, Y., Katsaros, D., & 10 othersHuang, Q., Montone, K., Fan, Y., Coukos, G., Boyd, J., Sood, A. K., Rebbeck, T., Mills, G. B., Dang, C. V. & Zhang, L., Oct 12 2015, In: Cancer cell. 28, 4, p. 529-540 12 p., 2143.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      545 Scopus citations

    • Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

      Ciriello, G., Gatza, M. L., Beck, A. H., Wilkerson, M. D., Rhie, S. K., Pastore, A., Zhang, H., McLellan, M., Yau, C., Kandoth, C., Bowlby, R., Shen, H., Hayat, S., Fieldhouse, R., Lester, S. C., Tse, G. M. K., Factor, R. E., Collins, L. C., Allison, K. H., Chen, Y. Y., & 119 othersJensen, K., Johnson, N. B., Oesterreich, S., Mills, G. B., Cherniack, A. D., Robertson, G., Benz, C., Sander, C., Laird, P. W., Hoadley, K. A., King, T. A., Akbani, R., Auman, J. T., Balasundaram, M., Balu, S., Barr, T., Benz, S., Berrios, M., Beroukhim, R., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Brooks, D., Chin, L., Cho, J., Chudamani, S., Davidsen, T., Demchok, J. A., Dennison, J. B., Ding, L., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gao, J. J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gibson, W. J., Hayes, D. N., Heiman, D. I., Holbrook, A., Holt, R. A., Hoyle, A. P., Hu, H., Huang, M., Hutter, C. M., Hwang, E. S., Jefferys, S. R., Jones, S. J. M., Ju, Z., Kim, J., Lai, P. H., Lawrence, M. S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Ling, S., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Mardis, E., Marks, J., Marra, M. A., McAllister, C., Meng, S., Meyerson, M., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Olopade, O., Parker, J. S., Pihl, T., Saksena, G., Schumacher, S. E., Shaw, K. R. M., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Schein, J. E., Schultz, N., Sheth, M., Shi, Y., Shih, J., Shelley, C. S., Shriver, C., Simons, J. V., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tarnuzzer, R., Tiezzi, D. G., Van Den Berg, D. J., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wilson, R., Wise, L., Wiznerowicz, M., Wu, J., Wu, Y., Yang, L., Zack, T. I., Zenklusen, J. C., Zhang, J., Zmuda, E. & Perou, C. M., Oct 8 2015, In: Cell. 163, 2, p. 506-519 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1290 Scopus citations

    • Cupid: Simultaneous reconstruction of micrornatarget and cerna networks

      Chiu, H. S., Llobet-Navas, D., Yang, X., Chung, W. J., Ambesi-Impiombato, A., Iyer, A., Kim, H. R., Seviour, E. G., Luo, Z., Sehgal, V., Moss, T., Lu, Y., Ram, P., Silva, J., Mills, G. B., Califano, A. & Sumazin, P., Feb 1 2015, In: Genome research. 25, 2, p. 257-267 11 p.

      Research output: Contribution to journal › Article › peer-review

      82 Scopus citations

    • Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

      Korkola, J. E., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T., Tomlin, C., & 3 othersMukherjee, S., Gray, J. W. & Jakkula, L., Jul 16 2015, In: PloS one. 10, 7, e0133219.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      17 Scopus citations