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20042024

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  • 2024

    Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer

    Jahangir, C. A., Page, D. B., Broeckx, G., Gonzalez, C. A., Burke, C., Murphy, C., Reis-Filho, J. S., Ly, A., Harms, P. W., Gupta, R. R., Vieth, M., Hida, A. I., Kahila, M., Kos, Z., van Diest, P. J., Verbandt, S., Thagaard, J., Khiroya, R., Abduljabbar, K., Acosta Haab, G., & 117 othersAcs, B., Adams, S., Almeida, J. S., Alvarado-Cabrero, I., Azmoudeh-Ardalan, F., Badve, S., Baharun, N. B., Bellolio, E. R., Bheemaraju, V., Blenman, K. R. M., Botinelly Mendonça Fujimoto, L., Burgues, O., Chardas, A., Cheang, M. C. U., Ciompi, F., Cooper, L. A. D., Coosemans, A., Corredor, G., Dantas Portela, F. L., Deman, F., Demaria, S., Dudgeon, S. N., Elghazawy, M., Fernandez-Martín, C., Fineberg, S., Fox, S. B., Giltnane, J. M., Gnjatic, S., Gonzalez-Ericsson, P. I., Grigoriadis, A., Halama, N., Hanna, M. G., Harbhajanka, A., Hart, S. N., Hartman, J., Hewitt, S., Horlings, H. M., Husain, Z., Irshad, S., Janssen, E. A. M., Kataoka, T. R., Kawaguchi, K., Khramtsov, A. I., Kiraz, U., Kirtani, P., Kodach, L. L., Korski, K., Akturk, G., Scott, E., Kovács, A., Lænkholm, A. V., Lang-Schwarz, C., Larsimont, D., Lennerz, J. K., Lerousseau, M., Li, X., Madabhushi, A., Maley, S. K., Manur Narasimhamurthy, V., Marks, D. K., McDonald, E. S., Mehrotra, R., Michiels, S., Kharidehal, D., Minhas, F. U. A. A., Mittal, S., Moore, D. A., Mushtaq, S., Nighat, H., Papathomas, T., Penault-Llorca, F., Perera, R. D., Pinard, C. J., Pinto-Cardenas, J. C., Pruneri, G., Pusztai, L., Rajpoot, N. M., Rapoport, B. L., Rau, T. T., Ribeiro, J. M., Rimm, D., Vincent-Salomon, A., Saltz, J., Sayed, S., Hytopoulos, E., Mahon, S., Siziopikou, K. P., Sotiriou, C., Stenzinger, A., Sughayer, M., Sur, D., Symmans, F., Tanaka, S., Taxter, T., Tejpar, S., Teuwen, J., Thompson, E. A., Tramm, T., Tran, W. T., van der Laak, J., Verghese, G. E., Viale, G., Wahab, N., Walter, T., Waumans, Y., Wen, H. Y., Yang, W., Yuan, Y., Bartlett, J., Loibl, S., Denkert, C., Savas, P., Loi, S., Specht Stovgaard, E., Salgado, R., Gallagher, W. M. & Rahman, A., Mar 2024, In: Journal of Pathology. 262, 3, p. 271-288 18 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
  • 2023

    Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: a report of the international immuno-oncology biomarker working group

    Thagaard, J., Broeckx, G., Page, D. B., Jahangir, C. A., Verbandt, S., Kos, Z., Gupta, R., Khiroya, R., Abduljabbar, K., Acosta Haab, G., Acs, B., Akturk, G., Almeida, J. S., Alvarado-Cabrero, I., Amgad, M., Azmoudeh-Ardalan, F., Badve, S., Baharun, N. B., Balslev, E., Bellolio, E. R., & 122 othersBheemaraju, V., Blenman, K. R. M., Botinelly Mendonça Fujimoto, L., Bouchmaa, N., Burgues, O., Chardas, A., Chon U Cheang, M., Ciompi, F., Cooper, L. A. D., Coosemans, A., Corredor, G., Dahl, A. B., Dantas Portela, F. L., Deman, F., Demaria, S., Doré Hansen, J., Dudgeon, S. N., Ebstrup, T., Elghazawy, M., Fernandez-Martín, C., Fox, S. B., Gallagher, W. M., Giltnane, J. M., Gnjatic, S., Gonzalez-Ericsson, P. I., Grigoriadis, A., Halama, N., Hanna, M. G., Harbhajanka, A., Hart, S. N., Hartman, J., Hauberg, S., Hewitt, S., Hida, A. I., Horlings, H. M., Husain, Z., Hytopoulos, E., Irshad, S., Janssen, E. A. M., Kahila, M., Kataoka, T. R., Kawaguchi, K., Kharidehal, D., Khramtsov, A. I., Kiraz, U., Kirtani, P., Kodach, L. L., Korski, K., Kovács, A., Laenkholm, A. V., Lang-Schwarz, C., Larsimont, D., Lennerz, J. K., Lerousseau, M., Li, X., Ly, A., Madabhushi, A., Maley, S. K., Manur Narasimhamurthy, V., Marks, D. K., McDonald, E. S., Mehrotra, R., Michiels, S., Minhas, F. U. A. A., Mittal, S., Moore, D. A., Mushtaq, S., Nighat, H., Papathomas, T., Penault-Llorca, F., Perera, R. D., Pinard, C. J., Pinto-Cardenas, J. C., Pruneri, G., Pusztai, L., Rahman, A., Rajpoot, N. M., Rapoport, B. L., Rau, T. T., Reis-Filho, J. S., Ribeiro, J. M., Rimm, D., Roslind, A., Vincent-Salomon, A., Salto-Tellez, M., Saltz, J., Sayed, S., Scott, E., Siziopikou, K. P., Sotiriou, C., Stenzinger, A., Sughayer, M. A., Sur, D., Fineberg, S., Symmans, F., Tanaka, S., Taxter, T., Tejpar, S., Teuwen, J., Thompson, E. A., Tramm, T., Tran, W. T., van der Laak, J., van Diest, P. J., Verghese, G. E., Viale, G., Vieth, M., Wahab, N., Walter, T., Waumans, Y., Wen, H. Y., Yang, W., Yuan, Y., Zin, R. M., Adams, S., Bartlett, J., Loibl, S., Denkert, C., Savas, P., Loi, S., Salgado, R. & Specht Stovgaard, E., Aug 2023, In: Journal of Pathology. 260, 5, p. 498-513 16 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    5 Scopus citations
  • Spatial analyses of immune cell infiltration in cancer: current methods and future directions. A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer

    Page, D. B., Broeckx, G., Jahangir, C. A., Verbandt, S., Gupta, R. R., Thagaard, J., Khiroya, R., Kos, Z., Abduljabbar, K., Acosta Haab, G., Acs, B., Akturk, G., Almeida, J. S., Alvarado-Cabrero, I., Azmoudeh-Ardalan, F., Badve, S., Baharun, N. B., Bellolio, E. R., Bheemaraju, V., Blenman, K. R. M., & 114 othersBotinelly Mendonça Fujimoto, L., Bouchmaa, N., Burgues, O., Cheang, M. C. U., Ciompi, F., Cooper, L. A. D., Coosemans, A., Corredor, G., Dantas Portela, F. L., Deman, F., Demaria, S., Dudgeon, S. N., Elghazawy, M., Ely, S., Fernandez-Martín, C., Fineberg, S., Fox, S. B., Gallagher, W. M., Giltnane, J. M., Gnjatic, S., Gonzalez-Ericsson, P. I., Grigoriadis, A., Halama, N., Hanna, M. G., Harbhajanka, A., Hardas, A., Hart, S. N., Hartman, J., Hewitt, S., Hida, A. I., Horlings, H. M., Husain, Z., Hytopoulos, E., Irshad, S., Janssen, E. A. M., Kahila, M., Kataoka, T. R., Kawaguchi, K., Kharidehal, D., Khramtsov, A. I., Kiraz, U., Kirtani, P., Kodach, L. L., Korski, K., Kovács, A., Laenkholm, A. V., Lang-Schwarz, C., Larsimont, D., Lennerz, J. K., Lerousseau, M., Li, X., Ly, A., Madabhushi, A., Maley, S. K., Manur Narasimhamurthy, V., Marks, D. K., McDonald, E. S., Mehrotra, R., Michiels, S., Minhas, F. U. A. A., Mittal, S., Moore, D. A., Mushtaq, S., Nighat, H., Papathomas, T., Penault-Llorca, F., Perera, R. D., Pinard, C. J., Pinto-Cardenas, J. C., Pruneri, G., Pusztai, L., Rahman, A., Rajpoot, N. M., Rapoport, B. L., Rau, T. T., Reis-Filho, J. S., Ribeiro, J. M., Rimm, D., Vincent-Salomon, A., Salto-Tellez, M., Saltz, J., Sayed, S., Siziopikou, K. P., Sotiriou, C., Stenzinger, A., Sughayer, M. A., Sur, D., Symmans, F., Tanaka, S., Taxter, T., Tejpar, S., Teuwen, J., Thompson, E. A., Tramm, T., Tran, W. T., van der Laak, J., van Diest, P. J., Verghese, G. E., Viale, G., Vieth, M., Wahab, N., Walter, T., Waumans, Y., Wen, H. Y., Yang, W., Yuan, Y., Adams, S., Bartlett, J. M. S., Loibl, S., Denkert, C., Savas, P., Loi, S., Salgado, R. & Specht Stovgaard, E., Aug 2023, In: Journal of Pathology. 260, 5, p. 514-532 19 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    3 Scopus citations
  • The tumour ecology of quiescence: Niches across scales of complexity

    Castillo, S. P., Galvez-Cancino, F., Liu, J., Pollard, S. M., Quezada, S. A. & Yuan, Y., Jul 2023, In: Seminars in cancer biology. 92, p. 139-149 11 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    1 Scopus citations
  • 2022

    Comparative Evaluation of Tumor-Infiltrating Lymphocytes in Companion Animals: Immuno-Oncology as a Relevant Translational Model for Cancer Therapy

    on behalf of the International Immuno-Oncology Biomarker Working Group, Oct 2022, In: Cancers. 14, 20, 5008.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    4 Scopus citations
  • Emerging technologies and their impact on regulatory science

    Anklam, E., Bahl, M. I., Ball, R., Beger, R. D., Cohen, J., Fitzpatrick, S., Girard, P., Halamoda-Kenzaoui, B., Hinton, D., Hirose, A., Hoeveler, A., Honma, M., Hugas, M., Ishida, S., Kass, G. E. N., Kojima, H., Krefting, I., Liachenko, S., Liu, Y., Masters, S., & 28 othersMarx, U., McCarthy, T., Mercer, T., Patri, A., Pelaez, C., Pirmohamed, M., Platz, S., Ribeiro, A. J. S., Rodricks, J. V., Rusyn, I., Salek, R. M., Schoonjans, R., Silva, P., Svendsen, C. N., Sumner, S., Sung, K., Tagle, D., Tong, L., Tong, W., Eijnden-van-Raaij, J. V. D., Vary, N., Wang, T., Waterton, J., Wang, M., Wen, H., Wishart, D., Yuan, Y. & Slikker, W., Jan 2022, In: Experimental Biology and Medicine. 247, 1, p. 1-75 75 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    19 Scopus citations
  • Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

    International Immuno-Oncology Biomarker Working Group, Dec 2022, In: npj Breast Cancer. 6, 1, 16.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    86 Scopus citations
  • 2021

    Artificial intelligence and digital pathology: Opportunities and implications for immuno-oncology

    Sobhani, F., Robinson, R., Hamidinekoo, A., Roxanis, I., Somaiah, N. & Yuan, Y., Apr 2021, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1875, 2, 188520.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    17 Scopus citations
  • The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

    the International Immuno-Oncology Biomarker Working Group, Dec 1 2021, In: npj Breast Cancer. 7, 1, 150.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    101 Scopus citations
  • 2020

    Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

    International Immuno-Oncology Biomarker Working Group, Dec 1 2020, In: npj Breast Cancer. 6, 1, 15.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    12 Scopus citations
  • The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

    Human Tumor Atlas Network, Apr 16 2020, In: Cell. 181, 2, p. 236-249 14 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    248 Scopus citations
  • 2017

    Classifying the evolutionary and ecological features of neoplasms

    Maley, C. C., Aktipis, A., Graham, T. A., Sottoriva, A., Boddy, A. M., Janiszewska, M., Silva, A. S., Gerlinger, M., Yuan, Y., Pienta, K. J., Anderson, K. S., Gatenby, R., Swanton, C., Posada, D., Wu, C. I., Schiffman, J. D., Hwang, E. S., Polyak, K., Anderson, A. R. A., Brown, J. S., & 2 othersGreaves, M. & Shibata, D., Oct 1 2017, In: Nature Reviews Cancer. 17, 10, p. 605-619 15 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    257 Scopus citations
  • 2016

    Computational pathology: Exploring the spatial dimension of tumor ecology

    Nawaz, S. & Yuan, Y., Sep 1 2016, In: Cancer Letters. 380, 1, p. 296-303 8 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    47 Scopus citations