Abstract
We have been developing novel 3-dimensional (3D) detector systems using organic plastic and liquid scintillators to measure and image the dose distribution from proton therapy beams in near-real time. Proof-of-concept and initial feasibility studies using a single charge-coupled device camera have already been conducted. Our recent studies focused on the characterization of scanning proton beams used for patient treatments using a 3D liquid scintillator-based detector system with a set of scientific-complementary metal-oxide-semiconductor (sCMOS) cameras. The basic concept consists of using a large volume of a solid or liquid scintillator to measure or image the dose distributions from proton beams in 3D. We recently developed a large liquid scintillator-based detector system consisting of a 20 - 20 - 20cm transparent acrylic tank filled with a water-equivalent, commercially available liquid scintillator that generates scintillation light when irradiated with protons. To track rapid spatial and dose variations in spot-scanned proton beams, we used 3 high-speed sCMOS cameras to image the scintillation light signals from 3 orthogonal projections in cine mode. Furthermore, we developed a new image acquisition approach that synchronized camera imaging times with dynamic pencil-beam deliveries to efficiently capture the dose and therefore enable accurate dosimetric calculations. This system was fully developed and characterized at the Proton Therapy Center at The University of Texas MD Anderson Cancer Center. We show that such systems can provide fast and accurate measurements of the range, lateral profile, and lateral position of scanning proton beams with excellent spatial resolution (0.21 mm). We also demonstrate that such detectors can rapidly measure proton beam characteristics and intensities at multiple energies, which makes them an ideal tool for scanned proton-beam systems, beam quality assurance studies, and verification of patient treatment delivery.
| Original language | English (US) |
|---|---|
| Article number | 012038 |
| Journal | Journal of Physics: Conference Series |
| Volume | 1305 |
| Issue number | 1 |
| DOIs | |
| State | Published - Aug 29 2019 |
| Event | 10th International Conference on 3D Radiation Dosimetry, IC3DDose 2018 - Kunshan, China Duration: Sep 16 2018 → Sep 19 2018 |
Fingerprint
ASJC Scopus subject areas
- Physics and Astronomy(all)
Cite this
3D dosimetry for proton therapy. / Beddar, S.
In: Journal of Physics: Conference Series, Vol. 1305, No. 1, 012038, 29.08.2019.Research output: Contribution to journal › Conference article
}
TY - JOUR
T1 - 3D dosimetry for proton therapy
AU - Beddar, S.
PY - 2019/8/29
Y1 - 2019/8/29
N2 - We have been developing novel 3-dimensional (3D) detector systems using organic plastic and liquid scintillators to measure and image the dose distribution from proton therapy beams in near-real time. Proof-of-concept and initial feasibility studies using a single charge-coupled device camera have already been conducted. Our recent studies focused on the characterization of scanning proton beams used for patient treatments using a 3D liquid scintillator-based detector system with a set of scientific-complementary metal-oxide-semiconductor (sCMOS) cameras. The basic concept consists of using a large volume of a solid or liquid scintillator to measure or image the dose distributions from proton beams in 3D. We recently developed a large liquid scintillator-based detector system consisting of a 20 - 20 - 20cm transparent acrylic tank filled with a water-equivalent, commercially available liquid scintillator that generates scintillation light when irradiated with protons. To track rapid spatial and dose variations in spot-scanned proton beams, we used 3 high-speed sCMOS cameras to image the scintillation light signals from 3 orthogonal projections in cine mode. Furthermore, we developed a new image acquisition approach that synchronized camera imaging times with dynamic pencil-beam deliveries to efficiently capture the dose and therefore enable accurate dosimetric calculations. This system was fully developed and characterized at the Proton Therapy Center at The University of Texas MD Anderson Cancer Center. We show that such systems can provide fast and accurate measurements of the range, lateral profile, and lateral position of scanning proton beams with excellent spatial resolution (0.21 mm). We also demonstrate that such detectors can rapidly measure proton beam characteristics and intensities at multiple energies, which makes them an ideal tool for scanned proton-beam systems, beam quality assurance studies, and verification of patient treatment delivery.
AB - We have been developing novel 3-dimensional (3D) detector systems using organic plastic and liquid scintillators to measure and image the dose distribution from proton therapy beams in near-real time. Proof-of-concept and initial feasibility studies using a single charge-coupled device camera have already been conducted. Our recent studies focused on the characterization of scanning proton beams used for patient treatments using a 3D liquid scintillator-based detector system with a set of scientific-complementary metal-oxide-semiconductor (sCMOS) cameras. The basic concept consists of using a large volume of a solid or liquid scintillator to measure or image the dose distributions from proton beams in 3D. We recently developed a large liquid scintillator-based detector system consisting of a 20 - 20 - 20cm transparent acrylic tank filled with a water-equivalent, commercially available liquid scintillator that generates scintillation light when irradiated with protons. To track rapid spatial and dose variations in spot-scanned proton beams, we used 3 high-speed sCMOS cameras to image the scintillation light signals from 3 orthogonal projections in cine mode. Furthermore, we developed a new image acquisition approach that synchronized camera imaging times with dynamic pencil-beam deliveries to efficiently capture the dose and therefore enable accurate dosimetric calculations. This system was fully developed and characterized at the Proton Therapy Center at The University of Texas MD Anderson Cancer Center. We show that such systems can provide fast and accurate measurements of the range, lateral profile, and lateral position of scanning proton beams with excellent spatial resolution (0.21 mm). We also demonstrate that such detectors can rapidly measure proton beam characteristics and intensities at multiple energies, which makes them an ideal tool for scanned proton-beam systems, beam quality assurance studies, and verification of patient treatment delivery.
UR - http://www.scopus.com/inward/record.url?scp=85073598200&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85073598200&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1305/1/012038
DO - 10.1088/1742-6596/1305/1/012038
M3 - Conference article
AN - SCOPUS:85073598200
VL - 1305
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
SN - 1742-6588
IS - 1
M1 - 012038
ER -