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1997
Induction of p21(waf1) expression and growth inhibition by transforming growth factor β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells
Grau, A. M., Zhang, L., Wang, W., Ruan, S., Evans, D. B., Abbruzzese, J. L., Zhang, W. & Chiao, P. J., Sep 15 1997, In: Cancer Research. 57, 18, p. 3929-3934 6 p.Research output: Contribution to journal › Article › peer-review
146 Scopus citations -
2003
Mechanisms of proinflammatory cytokine-induced biphasic NF-κB activation
Schmidt, C., Peng, B., Li, Z., Sclabas, G. M., Fujioka, S., Niu, J., Schmidt-Supprian, M., Evans, D. B., Abbruzzese, J. L. & Chiao, P. J., Nov 2003, In: Molecular cell. 12, 5, p. 1287-1300 14 p.Research output: Contribution to journal › Article › peer-review
142 Scopus citations -
2011
Clinical and prognostic implications of plasma insulin-like growth factor-1 and vascular endothelial growth factor in patients with hepatocellular carcinoma
Kaseb, A. O., Morris, J., Hassan, M. M., Siddiqui, A. M., Lin, E., Xiao, L., Abdalla, E. K., Vauthey, J. N., Aloia, T. A., Krishnan, S. & Abbruzzese, J. L., Oct 11 2011, In: Journal of Clinical Oncology. 29, 29, p. 3892-3899 8 p.Research output: Contribution to journal › Article › peer-review
108 Scopus citations -
2003
Inhibition of constitutive NF-κB activity by IκBαM suppresses tumorigenesis
Fujioka, S., Sclabas, G. M., Schmidt, C., Niu, J., Frederick, W. A., Dong, Q. G., Abbruzzese, J. L., Evans, D. B., Baker, C. & Chiao, P. J., Mar 6 2003, In: Oncogene. 22, 9, p. 1365-1370 6 p.Research output: Contribution to journal › Article › peer-review
152 Scopus citations -
2004
Novel therapies for pancreatic adenocarcinoma
Pino, S. M., Xiong, H. Q., McConkey, D. & Abbruzzese, J. L., May 2004, In: Current oncology reports. 6, 3, p. 199-206 8 p.Research output: Contribution to journal › Review article › peer-review
22 Scopus citations -
2003
Randomized phase II comparison of dose-intense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
Tempero, M., Plunkett, W., Van Haperen, V. R., Hainsworth, J., Hochster, H., Lenzi, R. & Abbruzzese, J., Sep 15 2003, In: Journal of Clinical Oncology. 21, 18, p. 3402-3408 7 p.Research output: Contribution to journal › Article › peer-review
479 Scopus citations -
2014
SOX9: A useful marker for pancreatic ductal lineage of pancreatic neoplasms
Shroff, S., Rashid, A., Wang, H., Katz, M. H., Abbruzzese, J. L., Fleming, J. B. & Wang, H., Mar 2014, In: Human Pathology. 45, 3, p. 456-463 8 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
2008
Collagen IV levels are elevated in the serum of patients with primary breast cancer compared to healthy volunteers
Mazouni, C., Arun, B., André, F., Ayers, M., Krishnamurthy, S., Wang, B., Hortobagyi, G. N., Buzdar, A. U. & Pusztai, L., Jul 8 2008, In: British journal of cancer. 99, 1, p. 68-71 4 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
2011
Patient-controlled analgesia in patients with advanced cancer. Should patients be in control?
Dev, R., Del Fabbro, E. & Bruera, E., Aug 2011, In: Journal of pain and symptom management. 42, 2, p. 296-300 5 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2004
Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry
Shen, J., Person, M. D., Zhu, J., Abbruzzese, J. L. & Li, D., Dec 15 2004, In: Cancer Research. 64, 24, p. 9018-9026 9 p.Research output: Contribution to journal › Article › peer-review
Open Access299 Scopus citations -
2008
Effect of different types of smoking and synergism with Hepatitis C virus on risk of hepatocellular carcinoma in American men and wo men: Case-control study
Hassan, M. M., Spitz, M. R., Thomas, M. B., El-Deeb, A. S., Glover, K. Y., Nguyen, N. T., Chan, W., Kaseb, A., Curley, S. A., Vauthey, J. N., Ellis, L. M., Abdalla, E., Lozano, R. D., Patt, Y. Z., Brown, T. D., Abbruzzese, J. L. & Li, D., Oct 15 2008, In: International journal of cancer. 123, 8, p. 1883-1891 9 p.Research output: Contribution to journal › Article › peer-review
Open Access71 Scopus citations -
2011
V-CLIP: Integrating plasma vascular endothelial growth factor into a new scoring system to stratify patients with advanced hepatocellular carcinoma for clinical trials
Kaseb, A. O., Hassan, M. M., Lin, E., Xiao, L., Kumar, V., Pathak, P., Lozano, R., Rashid, A., Abbruzzese, J. L. & Morris, J., Jun 1 2011, In: Cancer. 117, 11, p. 2478-2488 11 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
1991
Saturation of 2′, 2′-difluorodeoxycytidine 5′-triphosphate accumulation by mononuclear cells during a phase I trial of gemcitabine
Grunewald, R., Abbruzzese, J. L., Tarassoff, P. & Plunkett, W., Jul 1991, In: Cancer chemotherapy and pharmacology. 27, 4, p. 258-262 5 p.Research output: Contribution to journal › Article › peer-review
245 Scopus citations -
2007
Differences in K-ras and p53 gene mutations among pancreatic adenocarcinomas associated with regional environmental pollution
Soliman, A. S., Lo, A. C., Banerjee, M., El-Ghawalby, N., Khaled, H. M., Bayoumi, S., Seifeldin, I. A., Abdel-Aziz, A., Abbruzzese, J. L., Greenson, J. K. & Hamilton, S. R., Aug 2007, In: Carcinogenesis. 28, 8, p. 1794-1799 6 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
'Unresectable' pancreatic cancer: Conceptual challenges
Fogelman, D. R. & Abbruzzese, J. L., Nov 2007, In: ONCOLOGY. 21, 13, p. 1571-1572 2 p.Research output: Contribution to journal › Review article › peer-review
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2012
Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release
Jayaraman, P., Parikh, F., Lopez-Rivera, E., Hailemichael, Y., Clark, A., Ma, G., Cannan, D., Ramacher, M., Kato, M., Overwijk, W. W., Chen, S. H., Umansky, V. Y. & Sikora, A. G., Jun 1 2012, In: Journal of Immunology. 188, 11, p. 5365-5376 12 p.Research output: Contribution to journal › Article › peer-review
139 Scopus citations -
2004
Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
Pérez-Soler, R., Chachoua, A., Hammond, L. A., Rowinsky, E. K., Huberman, M., Karp, D., Rigas, J., Clark, G. M., Santabárbara, P. & Bonomi, P., 2004, In: Journal of Clinical Oncology. 22, 16, p. 3238-3247 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1060 Scopus citations -
2007
TAK1-dependent signaling requires functional interaction with TAB2/TAB3
Besse, A., Lamothe, B., Campos, A. D., Webster, W. K., Maddineni, U., Lin, S. C., Wu, H. & Darnay, B. G., Jan 9 2007, In: Journal of Biological Chemistry. 282, 6, p. 3918-3928 11 p.Research output: Contribution to journal › Article › peer-review
113 Scopus citations -
2022
Repeat laser interstitial thermal therapy for recurrent primary and metastatic intracranial tumors
Muir, M., Traylor, J. I., Gadot, R., Patel, R. & Prabhu, S. S., 2022, In: Surgical Neurology International. 13, 311.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2009
Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array
Andre, F., Job, B., Dessen, P., Tordai, A., Michiels, S., Liedtke, C., Richon, C., Yan, K., Wang, B., Vassal, G., Delaloge, S., Hortobagyi, G. N., Symmans, W. F., Lazar, V. & Pusztai, L., Jan 15 2009, In: Clinical Cancer Research. 15, 2, p. 441-451 11 p.Research output: Contribution to journal › Article › peer-review
Open Access279 Scopus citations -
2010
Adolescent behavior and adult health status in childhood cancer survivors
Krull, K. R., Huang, S., Gurney, J. G., Klosky, J. L., Leisenring, W., Termuhlen, A., Ness, K. K., Srivastava, D. K., Mertens, A., Stovall, M., Robison, L. L. & Hudson, M. M., 2010, In: Journal of Cancer Survivorship. 4, 3, p. 210-217 8 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
2009
Antidiabetic Therapies Affect Risk of Pancreatic Cancer
Li, D., Yeung, S. C. J., Hassan, M. M., Konopleva, M. & Abbruzzese, J. L., Aug 2009, In: Gastroenterology. 137, 2, p. 482-488 7 p.Research output: Contribution to journal › Article › peer-review
Open Access524 Scopus citations -
2003
Developmental biology informs cancer: The emerging role of the hedgehog signaling pathway in upper gastrointestinal cancers
Xie, K. & Abbruzzese, J. L., Oct 2003, In: Cancer cell. 4, 4, p. 245-247 3 p.Research output: Contribution to journal › Review article › peer-review
73 Scopus citations -
2000
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
Steinbach, G., Lynch, P. M., Phillips, R. K. S., Wallace, M. H., Hawk, E., Gordon, G. B., Wakabayashi, N., Saunders, B., Shen, Y., Fujimura, T., Su, L. K., Levin, B., Godio, L., Patterson, S., Rodriguez-Bigas, M. A., Jester, S. L., King, K. L., Schumacher, M., Abbruzzese, J., DuBois, R. N., & 4 others , Jun 29 2000, In: New England Journal of Medicine. 342, 26, p. 1946-1952 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2347 Scopus citations -
2007
Effects of base excision repair gene polymorphisms on pancreatic cancer survival
Li, D., Li, Y., Jiao, L., Chang, D. Z., Beinart, G., Wolff, R. A., Evans, D. B., Hassan, M. M. & Abbruzzese, J. L., Apr 15 2007, In: International journal of cancer. 120, 8, p. 1748-1754 7 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2010
Association of diabetes duration and diabetes treatment with the risk of hepatocellular carcinoma
Hassan, M. M., Curley, S. A., Li, D., Kaseb, A., Davila, M., Abdalla, E. K., Javle, M., Moghazy, D. M., Lozano, R. D., Abbruzzese, J. L. & Vauthey, J. N., Apr 15 2010, In: Cancer. 116, 8, p. 1938-1946 9 p.Research output: Contribution to journal › Article › peer-review
Open Access263 Scopus citations -
2013
Modified cisplatin/interferon α-2b/doxorubicin/5-fluorouracil (PIAF) chemotherapy in patients with no hepatitis or cirrhosis is associated with improved response rate, resectability, and survival of initially unresectable hepatocellular carcinoma
Kaseb, A. O., Shindoh, J., Patt, Y. Z., Roses, R. E., Zimmitti, G., Lozano, R. D., Hassan, M. M., Hassabo, H. M., Curley, S. A., Aloia, T. A., Abbruzzese, J. L. & Vauthey, J. N., Sep 15 2013, In: Cancer. 119, 18, p. 3334-3342 9 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
1988
Phase II study of fludarabine phosphate in patients with advanced colorectal carcinoma
Ajani, J. A., Abbruzzese, J. L., Faintuch, J. S., Blackburn, R., Levin, B. & Boman, B. M., Apr 1988, In: Investigational New Drugs. 6, 1, p. 47-50 4 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2011
Genesde proliferacioń y apoptosis como factores predictivos y pronósticos en el ćancer de mama: Hacia una medicina personalizada
Maldonado-Martinez, H., Pluma-Jiménez, M. Á., Grajales-Álvarez, R., Guadarrama-Orozco, J., Valero-Castillo, V., Silva, A., Ochoa-Carrillo, F. J., Baeza-Ramírez, I. & Astudillo-de La Vega, H., Jul 2011, In: Gaceta Mexicana de Oncologia. 10, 4, p. 210-221 12 p.Translated title of the contribution :Proliferation and apoptosis genes as prognostic and predictive factors in breast cancer: Towards personalized medicine Research output: Contribution to journal › Review article › peer-review
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2021
Epigenetic control of Cdkn2a.Arf protects tumor-infiltrating lymphocytes from metabolic exhaustion
Koss, B., Shields, B. D., Taylor, E. M., Storey, A. J., Byrum, S. D., Gies, A. J., Washam, C. L., Choudhury, S. R., Ahn, J. H., Uryu, H., Williams, J. B., Krager, K. J., Chiang, T. C., Mackintosh, S. G., Edmondson, R. D., Aykin-Burns, N., Gajewski, T. F., Wang, G. G. & Tackett, A. J., Nov 1 2021, In: Cancer Research. 80, 21, p. 4707-4719 13 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2009
Phase II study of capecitabine and oxaliplatin for advanced adenocarcinoma of the small bowel and ampulla of vater
Overman, M. J., Varadhachary, G. R., Kopetz, S., Adinin, R., Lin, E., Morris, J., Eng, C., Abbruzzese, J. L. & Wolff, R. A., Jun 1 2009, In: Journal of Clinical Oncology. 27, 16, p. 2598-2603 6 p.Research output: Contribution to journal › Article › peer-review
193 Scopus citations -
1992
Phase II trial of fazarabine in advanced colorectal carcinoma
Hubbard, K. P., Daugherty, K., Ajani, J. A., Pazdur, R., Levin, B. & Abbruzzese, J. L., Mar 1992, In: Investigational New Drugs. 10, 1, p. 39-42 4 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2020
The Utility of Digital Anal Rectal Examinations in a Public Health Screening Program for Anal Cancer
Nyitray, A. G., D'Souza, G., Stier, E. A., Clifford, G. & Chiao, E. Y., Apr 1 2020, In: Journal of lower genital tract disease. 24, 2, p. 192-196 5 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2009
Reply
Hassan, M. M. & Abbruzzese, J. L., 2009, In: Hepatology. 50, 3, p. 994 1 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
2006
Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival
Li, D., Liu, H., Jiao, L., Chang, D. Z., Beinart, G., Wolff, R. A., Evans, D. B., Hassan, M. M. & Abbruzzese, J. L., Mar 15 2006, In: Cancer Research. 66, 6, p. 3323-3330 8 p.Research output: Contribution to journal › Article › peer-review
Open Access73 Scopus citations -
2023
Myeloid cell-targeted therapies for solid tumours
Goswami, S., Anandhan, S., Raychaudhuri, D. & Sharma, P., Feb 2023, In: Nature Reviews Immunology. 23, 2, p. 106-120 15 p.Research output: Contribution to journal › Review article › peer-review
63 Scopus citations -
2009
Barriers to integrating gene profiling for stage II colon cancer
Kopetz, S. & Abbruzzese, J. L., Dec 15 2009, In: Clinical Cancer Research. 15, 24, p. 7451-7452 2 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2017
Epidemiology and Prognosis of Primary Periocular Sweat Gland Carcinomas
Baker, M. S., Yin, V. T., Ivan, D., Allen, R. C., Carter, K. D., Esmaeli, B. & Shriver, E. M., 2017, In: Ophthalmic plastic and reconstructive surgery. 33, 2, p. 101-105 5 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Potential susceptibility loci identified for renal cell carcinoma by targeting obesity-related genes
Shu, X., Purdue, M. P., Ye, Y., Tu, H., Wood, C. G., Tannir, N. M., Wang, Z., Albanes, D., Gapstur, S. M., Stevens, V. L., Rothman, N., Chanock, S. J. & Wu, X., Sep 1 2017, In: Cancer Epidemiology Biomarkers and Prevention. 26, 9, p. 1436-1442 7 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2014
Carcinoma of Unknown Primary
Varadhachary, G. R., Lenzi, R., Raber, M. N. & Abbruzzese, J. L., 2014, Abeloff's Clinical Oncology: Fifth Edition. Elsevier Inc., p. 1792-1803.e2Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
2018
Pain Management in the Era of the Opioid Crisis
Bruera, E. & Del Fabbro, E., May 23 2018, In: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. 38, p. 807-812 6 p.Research output: Contribution to journal › Review article › peer-review
22 Scopus citations -
2014
Pathological unfoldomics of uncontrolled chaos: Intrinsically disordered proteins and human diseases
Uversky, V. N., Davé, V., Iakoucheva, L. M., Malaney, P., Metallo, S. J., Pathak, R. R. & Joerger, A. C., Jul 9 2014, In: Chemical Reviews. 114, 13, p. 6844-6879 36 p.Research output: Contribution to journal › Review article › peer-review
Open Access208 Scopus citations -
2022
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function
Dierickx, P., Zhu, K., Carpenter, B. J., Jiang, C., Vermunt, M. W., Xiao, Y., Luongo, T. S., Yamamoto, T., Martí-Pàmies, Í., Mia, S., Latimer, M., Diwan, A., Zhao, J., Hauck, A. K., Krusen, B., Nguyen, H. C. B., Blobel, G. A., Kelly, D. P., Pei, L., Baur, J. A., & 2 others , Jan 2022, In: Nature Cardiovascular Research. 1, 1, p. 45-58 14 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2011
Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer
Lochhead, P., Ng, M. T. H., Hold, G. L., Rabkin, C. S., Vaughan, T. L., Gammon, M. D., Risch, H. A., Lissowska, J., Mukhopadhya, I., Chow, W. H. & El-Omar, E. M., Jan 2011, In: European Journal of Cancer Prevention. 20, 1, p. 54-57 4 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
2007
IKKβ Suppression of TSC1 Links Inflammation and Tumor Angiogenesis via the mTOR Pathway
Lee, D. F., Kuo, H. P., Chen, C. T., Hsu, J. M., Chou, C. K., Wei, Y., Sun, H. L., Li, L. Y., Ping, B., Huang, W. C., He, X., Hung, J. Y., Lai, C. C., Ding, Q., Su, J. L., Yang, J. Y., Sahin, A. A., Hortobagyi, G. N., Tsai, F. J., Tsai, C. H., & 1 others , Aug 10 2007, In: Cell. 130, 3, p. 440-455 16 p.Research output: Contribution to journal › Article › peer-review
556 Scopus citations -
1998
Functional analysis of Gscl in the pathogenesis of the DiGeorge and velocardiofacial syndromes
Wakamiya, M., Lindsay, E. A., Rivera-Pérez, J. A., Baldini, A. & Behringer, R. R., Nov 1998, In: Human molecular genetics. 7, 12, p. 1835-1840 6 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
2008
A cancer incidence survey in Tianjin: The third largest city in China - Between 1981 and 2000
Song, F., He, M., Li, H., Qian, B., Wei, Q., Zhang, W., Chen, K. & Hao, X., Jun 2008, In: Cancer Causes and Control. 19, 5, p. 443-450 8 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
2006
Surveillance for recurrent bladder cancer using a point-of-care proteomic assay
Barton Grossman, H., Soloway, M., Messing, E., Katz, G., Stein, B., Kassabian, V. & Shen, Y., Jan 18 2006, In: JAMA. 295, 3, p. 299-305 7 p.Research output: Contribution to journal › Article › peer-review
231 Scopus citations -
2007
Intensity of CNS treatment for pediatric cancer: Prediction of social outcomes in survivors
Vannatta, K., Gerhardt, C. A., Wells, R. J. & Noll, R. B., Oct 15 2007, In: Pediatric Blood and Cancer. 49, 5, p. 716-722 7 p.Research output: Contribution to journal › Article › peer-review
92 Scopus citations -
1987
Sustained recovery of hematopoiesis and immunity following transplantation of fetal liver cells in dogs.
Champlin, R. E., Cain, G., Stitzel, K. & Gale, R. P., 1987, In: Thymus. 10, 1-2, p. 13-18 6 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations