A 2D-spline patient specific model for use in radiation therapy

Hadi Fayad, Tinsu Pan, Christian Roux, Catherine Cheze Le Rest, Olivier Pradier, Dimitris Visvikis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Abstract

Modeling of respiratory motion is very important for the efficacy of radiation therapy (RT) which is used in the treatment of cancer in the thorax and the abdomen. Having such a model is a key point to deliver, under breathing induced motion, less dose to the normal healthy tissues and higher dose to the tumor. Many methods have been developed to reduce the respiratory motion induced errors. While 4D CT based methods produce a number of separate frames at different positions in the respiratory cycle, a continuous motion model will be more efficient for radiation therapy. In this paper, we describe an approach based on the creation of a continuous patient specific model that takes into account respiratory signal irregularities and reproduces respiration-induced organ motion. This model has been validated on three patients. Our results show that including both phase and amplitude for the model reconstruction leads to higher accuracy compared to the use of only one of these two parameters.

Original languageEnglish (US)
Title of host publicationProceedings - 2009 IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2009
Pages590-593
Number of pages4
DOIs
StatePublished - 2009
Event2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 - Boston, MA, United States
Duration: Jun 28 2009Jul 1 2009

Publication series

NameProceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009

Other

Other2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
Country/TerritoryUnited States
CityBoston, MA
Period6/28/097/1/09

Keywords

  • 2D bspline
  • Radiation therapy
  • Respiratory motion modeling

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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