Abstract
Proton therapy is an advanced form of radiation delivery for cancer treatment. Precise energy deposition of protons allows treatment planners to deliver a highly conformal radiation dose to the target volume while sparing the surrounding normal tissues. We have developed a mixed integer programming model for selecting treatment angles for Intensity Modulated Proton Therapy (IMPT) treatment planning in 3D modulation. The optimization model determines a set of treatment beam angles and their optimal weights, simultaneously. We assume that number of treatment angles and radiation dose contribution matrix are given as input. We tested our method on a prostate cancer case obtained from a hospital. Superb quality of treatment plans were produced using as few as two angles.
| Original language | English (US) |
|---|---|
| State | Published - 2010 |
| Externally published | Yes |
| Event | IIE Annual Conference and Expo 2010 - Cancun, Mexico Duration: Jun 5 2010 → Jun 9 2010 |
Other
| Other | IIE Annual Conference and Expo 2010 |
|---|---|
| Country/Territory | Mexico |
| City | Cancun |
| Period | 6/5/10 → 6/9/10 |
Keywords
- Beam angle optimization
- Cancer treatment planning
- IMPT
ASJC Scopus subject areas
- Industrial and Manufacturing Engineering