A case of sudden hearing loss in a patient with chronic myelomonocytic leukemia

Rodrick Babakhanlou; Marc Elie Nader; Yesid Alvarado

doi:10.1007/s00277-023-05433-w

A case of sudden hearing loss in a patient with chronic myelomonocytic leukemia

Rodrick Babakhanlou, Marc Elie Nader, Yesid Alvarado

Leukemia

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic myelomonocytic leukemia is a myeloid stem cell disease characterized by an abnormal production and accumulation of monocytic cells in association with other signs of myeloproliferation. Extramedullary manifestations of CMML are common and can affect the spleen, liver skin, and lymph nodes. However, otologic manifestations are extremely rare and could have occurred from either direct leukemic infiltration, hemorrhage of the cochlea, labyrinth, leukostasis, or infection. There is no standard treatment protocol for sensorineural hearing loss in CMML patients. More research is needed to improve the understanding of the pathogenesis of this condition, in order to provide better treatment options.

Original language	English (US)
Pages (from-to)	3427-3430
Number of pages	4
Journal	Annals of Hematology
Volume	102
Issue number	12
DOIs	https://doi.org/10.1007/s00277-023-05433-w
State	Published - Dec 2023

Keywords

Chronic myelomonocytic leukemia
CMML
Hearing loss
Leukemia
Sensorineural hearing loss

ASJC Scopus subject areas

Hematology

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10.1007/s00277-023-05433-w

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abstract = "Chronic myelomonocytic leukemia is a myeloid stem cell disease characterized by an abnormal production and accumulation of monocytic cells in association with other signs of myeloproliferation. Extramedullary manifestations of CMML are common and can affect the spleen, liver skin, and lymph nodes. However, otologic manifestations are extremely rare and could have occurred from either direct leukemic infiltration, hemorrhage of the cochlea, labyrinth, leukostasis, or infection. There is no standard treatment protocol for sensorineural hearing loss in CMML patients. More research is needed to improve the understanding of the pathogenesis of this condition, in order to provide better treatment options.",

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AB - Chronic myelomonocytic leukemia is a myeloid stem cell disease characterized by an abnormal production and accumulation of monocytic cells in association with other signs of myeloproliferation. Extramedullary manifestations of CMML are common and can affect the spleen, liver skin, and lymph nodes. However, otologic manifestations are extremely rare and could have occurred from either direct leukemic infiltration, hemorrhage of the cochlea, labyrinth, leukostasis, or infection. There is no standard treatment protocol for sensorineural hearing loss in CMML patients. More research is needed to improve the understanding of the pathogenesis of this condition, in order to provide better treatment options.

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A case of sudden hearing loss in a patient with chronic myelomonocytic leukemia

Abstract

Keywords

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