TY - JOUR
T1 - A comparison of four-image reconstruction algorithms for 3-D PET imaging of MDAPET camera using phantom data
AU - Baghaei, Hossain
AU - Wong, Wai Hoi
AU - Uribe, Jorge
AU - Li, Hongdi
AU - Wang, Yu
AU - Liu, Yaqiang
AU - Xing, Tao
AU - Ramirez, Rocio
AU - Xie, Shuping
AU - Kim, Soonseok
N1 - Funding Information:
Manuscript received November 9, 2003; revised April 27, 2004. This work was supported in part by the NIH-CA58980 PHS Grant, NIH-CA61880 PHS Grant, NIH-CA76246 PHS Grant, NIH-CA58980S PHS Grant, NIH-EB01481 PHS Grant, NIH-EB00217 PHS Grant, NIH-EB01038 PHS Grant, U.S. Army-Breast Cancer Research Grant, and the Texas ARP/ATP Grant 003657-0058-2001.
PY - 2004/10
Y1 - 2004/10
N2 - We compared two fully three-dimensional (3-D) image reconstruction algorithms and two 3-D rebinning algorithms followed by reconstruction with a two-dimensional (2-D) filtered-backprojection algorithm for 3-D positron emission tomography (PET) imaging. The two 3-D image reconstruction algorithms were ordered-subsets expectation-maximization (3D-OSEM) and 3-D reprojection (3DRP) algorithms. The two rebinning algorithms were Fourier rebinning (FORE) and single slice rebinning (SSRB). The 3-D projection data used for this work were acquired with a high-resolution PET scanner (MDAPET) with an intrinsic transaxial resolution of 2.8 mm. The scanner has 14 detector rings covering an axial field-of-view of 38.5 mm. We scanned three phantoms: 1) a uniform cylindrical phantom with inner diameter of 21.5 cm; 2) a uniform 11.5-cm cylindrical phantom with four embedded small hot lesions with diameters of 3, 4, 5, and 6 mm; and 3) the 3-D Hoffman brain phantom with three embedded small hot lesion phantoms with diameters of 3, 5, and 8.6 nun in a warm background. Lesions were placed at different radial and axial distances. We evaluated the different reconstruction methods for MDAPET camera by comparing the noise level of images, contrast recovery, and hot lesion detection, and visually compared images. We found that overall the 3D-OSEM algorithm, especially when images post filtered with the Metz filter, produced the best results in terms of contrast-noise tradeoff, and detection of hot spots, and reproduction of brain phantom structures. Even though the MDAPET camera has a relatively small maximum axial acceptance (±5 deg), images produced with the 3DRP algorithm had slightly better contrast recovery and reproduced the structures of the brain phantom slightly better than the faster 2-D rebinning methods.
AB - We compared two fully three-dimensional (3-D) image reconstruction algorithms and two 3-D rebinning algorithms followed by reconstruction with a two-dimensional (2-D) filtered-backprojection algorithm for 3-D positron emission tomography (PET) imaging. The two 3-D image reconstruction algorithms were ordered-subsets expectation-maximization (3D-OSEM) and 3-D reprojection (3DRP) algorithms. The two rebinning algorithms were Fourier rebinning (FORE) and single slice rebinning (SSRB). The 3-D projection data used for this work were acquired with a high-resolution PET scanner (MDAPET) with an intrinsic transaxial resolution of 2.8 mm. The scanner has 14 detector rings covering an axial field-of-view of 38.5 mm. We scanned three phantoms: 1) a uniform cylindrical phantom with inner diameter of 21.5 cm; 2) a uniform 11.5-cm cylindrical phantom with four embedded small hot lesions with diameters of 3, 4, 5, and 6 mm; and 3) the 3-D Hoffman brain phantom with three embedded small hot lesion phantoms with diameters of 3, 5, and 8.6 nun in a warm background. Lesions were placed at different radial and axial distances. We evaluated the different reconstruction methods for MDAPET camera by comparing the noise level of images, contrast recovery, and hot lesion detection, and visually compared images. We found that overall the 3D-OSEM algorithm, especially when images post filtered with the Metz filter, produced the best results in terms of contrast-noise tradeoff, and detection of hot spots, and reproduction of brain phantom structures. Even though the MDAPET camera has a relatively small maximum axial acceptance (±5 deg), images produced with the 3DRP algorithm had slightly better contrast recovery and reproduced the structures of the brain phantom slightly better than the faster 2-D rebinning methods.
KW - Filtered backprojection
KW - Image reconstruction
KW - Ordered-subsets expectation-maximization
KW - Positron emission tomography (PET)
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U2 - 10.1109/TNS.2004.834809
DO - 10.1109/TNS.2004.834809
M3 - Article
AN - SCOPUS:8344250334
SN - 0018-9499
VL - 51
SP - 2563
EP - 2569
JO - IEEE Transactions on Nuclear Science
JF - IEEE Transactions on Nuclear Science
IS - 5 II
ER -