A convenient synthesis of 2-(9H-fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid via N-Fmoc-thiourea

Kang Le; Robert A. Goodnow

doi:10.1081/SCC-120034173

A convenient synthesis of 2-(9H-fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid via N-Fmoc-thiourea

Kang Le, Robert A. Goodnow

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

2-(9H-Fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid has been prepared in high yield from 3-bromopyruvic acid and (aminothioxomethyl)carbamic acid 9H-fluoren-9-ylmethyl ester (N-Fmoc-thiourea) that was obtained from potassium thiocyanate.

Original language	English (US)
Pages (from-to)	1891-1895
Number of pages	5
Journal	Synthetic Communications
Volume	34
Issue number	10
DOIs	https://doi.org/10.1081/SCC-120034173
State	Published - 2004
Externally published	Yes

Keywords

2-(9H-Fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid
2-Aminothiazole-4-carboxylic acid
N-tert-butoxycarbonylthiourea

ASJC Scopus subject areas

Organic Chemistry

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10.1081/SCC-120034173

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title = "A convenient synthesis of 2-(9H-fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid via N-Fmoc-thiourea",

abstract = "2-(9H-Fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid has been prepared in high yield from 3-bromopyruvic acid and (aminothioxomethyl)carbamic acid 9H-fluoren-9-ylmethyl ester (N-Fmoc-thiourea) that was obtained from potassium thiocyanate.",

keywords = "2-(9H-Fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid, 2-Aminothiazole-4-carboxylic acid, N-tert-butoxycarbonylthiourea",

author = "Kang Le and Goodnow, {Robert A.}",

year = "2004",

doi = "10.1081/SCC-120034173",

language = "English (US)",

volume = "34",

pages = "1891--1895",

journal = "Synthetic Communications",

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T1 - A convenient synthesis of 2-(9H-fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid via N-Fmoc-thiourea

AU - Le, Kang

AU - Goodnow, Robert A.

PY - 2004

Y1 - 2004

N2 - 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid has been prepared in high yield from 3-bromopyruvic acid and (aminothioxomethyl)carbamic acid 9H-fluoren-9-ylmethyl ester (N-Fmoc-thiourea) that was obtained from potassium thiocyanate.

AB - 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid has been prepared in high yield from 3-bromopyruvic acid and (aminothioxomethyl)carbamic acid 9H-fluoren-9-ylmethyl ester (N-Fmoc-thiourea) that was obtained from potassium thiocyanate.

KW - 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid

KW - 2-Aminothiazole-4-carboxylic acid

KW - N-tert-butoxycarbonylthiourea

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UR - http://www.scopus.com/inward/citedby.url?scp=2942618702&partnerID=8YFLogxK

U2 - 10.1081/SCC-120034173

DO - 10.1081/SCC-120034173

M3 - Article

AN - SCOPUS:2942618702

SN - 0039-7911

VL - 34

SP - 1891

EP - 1895

JO - Synthetic Communications

JF - Synthetic Communications

IS - 10

ER -

A convenient synthesis of 2-(9H-fluoren-9-ylmethoxycarbonylamino)-thiazole-4-carboxylic acid via N-Fmoc-thiourea

Abstract

Keywords

ASJC Scopus subject areas

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