A Core System for the Implementation of Task Sets

Nico U.F. Dosenbach; Kristina M. Visscher; Erica D. Palmer; Francis M. Miezin; Kristin K. Wenger; Hyunseon C. Kang; E. Darcy Burgund; Ansley L. Grimes; Bradley L. Schlaggar; Steven E. Petersen

doi:10.1016/j.neuron.2006.04.031

A Core System for the Implementation of Task Sets

Nico U.F. Dosenbach, Kristina M. Visscher, Erica D. Palmer, Francis M. Miezin, Kristin K. Wenger, Hyunseon C. Kang, E. Darcy Burgund, Ansley L. Grimes, Bradley L. Schlaggar, Steven E. Petersen

Research output: Contribution to journal › Article › peer-review

1381 Scopus citations

Abstract

When performing tasks, humans are thought to adopt task sets that configure moment-to-moment data processing. Recently developed mixed blocked/event-related designs allow task set-related signals to be extracted in fMRI experiments, including activity related to cues that signal the beginning of a task block, "set-maintenance" activity sustained for the duration of a task block, and event-related signals for different trial types. Data were conjointly analyzed from mixed design experiments using ten different tasks and 183 subjects. Dorsal anterior cingulate cortex/medial superior frontal cortex (dACC/msFC) and bilateral anterior insula/frontal operculum (aI/fO) showed reliable start-cue and sustained activations across all or nearly all tasks. These regions also carried the most reliable error-related signals in a subset of tasks, suggesting that the regions form a "core" task-set system. Prefrontal regions commonly related to task control carried task-set signals in a smaller subset of tasks and lacked convergence across signal types.

Original language	English (US)
Pages (from-to)	799-812
Number of pages	14
Journal	Neuron
Volume	50
Issue number	5
DOIs	https://doi.org/10.1016/j.neuron.2006.04.031
State	Published - Jun 1 2006
Externally published	Yes

Keywords

SYSNEURO

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2006.04.031

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title = "A Core System for the Implementation of Task Sets",

abstract = "When performing tasks, humans are thought to adopt task sets that configure moment-to-moment data processing. Recently developed mixed blocked/event-related designs allow task set-related signals to be extracted in fMRI experiments, including activity related to cues that signal the beginning of a task block, {"}set-maintenance{"} activity sustained for the duration of a task block, and event-related signals for different trial types. Data were conjointly analyzed from mixed design experiments using ten different tasks and 183 subjects. Dorsal anterior cingulate cortex/medial superior frontal cortex (dACC/msFC) and bilateral anterior insula/frontal operculum (aI/fO) showed reliable start-cue and sustained activations across all or nearly all tasks. These regions also carried the most reliable error-related signals in a subset of tasks, suggesting that the regions form a {"}core{"} task-set system. Prefrontal regions commonly related to task control carried task-set signals in a smaller subset of tasks and lacked convergence across signal types.",

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note = "Funding Information: We thank Heather Lugar and Rebecca Coalson for their help with data collection. We thank Mark McAvoy for his help with data analysis. We thank Elizabeth Murray for pointing us toward the literature on insular infarcts. This work was supported by NIH grants NS41255 and NS46424 to SEP and the John Merck Scholars Fund, the Burroughs-Wellcome Fund, and the Dana Foundation (B.L.S.).",

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AU - Dosenbach, Nico U.F.

AU - Visscher, Kristina M.

AU - Palmer, Erica D.

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AU - Wenger, Kristin K.

AU - Kang, Hyunseon C.

AU - Burgund, E. Darcy

AU - Grimes, Ansley L.

AU - Schlaggar, Bradley L.

AU - Petersen, Steven E.

N1 - Funding Information: We thank Heather Lugar and Rebecca Coalson for their help with data collection. We thank Mark McAvoy for his help with data analysis. We thank Elizabeth Murray for pointing us toward the literature on insular infarcts. This work was supported by NIH grants NS41255 and NS46424 to SEP and the John Merck Scholars Fund, the Burroughs-Wellcome Fund, and the Dana Foundation (B.L.S.).

PY - 2006/6/1

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N2 - When performing tasks, humans are thought to adopt task sets that configure moment-to-moment data processing. Recently developed mixed blocked/event-related designs allow task set-related signals to be extracted in fMRI experiments, including activity related to cues that signal the beginning of a task block, "set-maintenance" activity sustained for the duration of a task block, and event-related signals for different trial types. Data were conjointly analyzed from mixed design experiments using ten different tasks and 183 subjects. Dorsal anterior cingulate cortex/medial superior frontal cortex (dACC/msFC) and bilateral anterior insula/frontal operculum (aI/fO) showed reliable start-cue and sustained activations across all or nearly all tasks. These regions also carried the most reliable error-related signals in a subset of tasks, suggesting that the regions form a "core" task-set system. Prefrontal regions commonly related to task control carried task-set signals in a smaller subset of tasks and lacked convergence across signal types.

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A Core System for the Implementation of Task Sets

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Keywords

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