TY - JOUR
T1 - A diagnostic approach to basaloid neoplasms of the skin
T2 - squamous is red; basals are blue but alas! If only that were true
AU - Liu, Yi Ariel
AU - Ciurea, Ana Mercedes
AU - Aung, Phyu P.
N1 - Publisher Copyright:
© 2023
PY - 2024/1
Y1 - 2024/1
N2 - Basaloid neoplasms of the skin are often challenging not only to general pathologists but also dermatopathologists especially in the setting of partial sampling. While basal cell carcinomas make up most cutaneous neoplasms, there is a wide variety of both benign and malignant entities that have a basaloid morphology, which are particularly important to distinguish when present on skin in sensitive areas. Distinguishing between the malignant from the benign requires an understanding of the clinical presentation, histological correlation, emergence of new subclassification, as well as molecular discoveries. This chapter will examine the common cutaneous basaloid neoplasms encountered in routine practice and will highlight pitfalls to avoid misdiagnosis of rare but aggressive mimics.
AB - Basaloid neoplasms of the skin are often challenging not only to general pathologists but also dermatopathologists especially in the setting of partial sampling. While basal cell carcinomas make up most cutaneous neoplasms, there is a wide variety of both benign and malignant entities that have a basaloid morphology, which are particularly important to distinguish when present on skin in sensitive areas. Distinguishing between the malignant from the benign requires an understanding of the clinical presentation, histological correlation, emergence of new subclassification, as well as molecular discoveries. This chapter will examine the common cutaneous basaloid neoplasms encountered in routine practice and will highlight pitfalls to avoid misdiagnosis of rare but aggressive mimics.
KW - Basal cell carcinoma
KW - basaloid neoplasms
KW - basaloid squamous cell carcinoma
KW - cutaneous adnexal neoplasms
KW - melanoma
KW - Merkel cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85175353998&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85175353998&partnerID=8YFLogxK
U2 - 10.1016/j.mpdhp.2023.10.006
DO - 10.1016/j.mpdhp.2023.10.006
M3 - Review article
AN - SCOPUS:85175353998
SN - 1756-2317
VL - 30
SP - 60
EP - 76
JO - Diagnostic Histopathology
JF - Diagnostic Histopathology
IS - 1
ER -