A Double-blind Study of Prazosin in the Treatment of Raynaud's Phenomenon in Scleroderma

Richard S. Surwit, Robert S. Gilgor, Lyle M. Allen, Madeleine Duvic

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Nineteen patients with Raynaud's phenomenon in conjunction with progressive systemic sclerosis were given either prazosin hydrochloride (1 mg orally three times a day) or a placebo for eight weeks, after which the treatment procedure was reversed for four weeks. Prazosin was shown to be effective in reducing both the frequency and the severity of vasospasm reported by the patients.

Original languageEnglish (US)
Pages (from-to)329-331
Number of pages3
JournalArchives of Dermatology
Volume120
Issue number3
DOIs
StatePublished - Mar 1984
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology

Fingerprint

Dive into the research topics of 'A Double-blind Study of Prazosin in the Treatment of Raynaud's Phenomenon in Scleroderma'. Together they form a unique fingerprint.

Cite this