A dual-layer TOF-DOI detector block for whole-body PET

Shitao Liu; Shaohui An; Hongdi Li; Chao Wang; Rocio A. Ramirez; Yuxuan Zhang; Hossain Baghaei; Wai Hoi Wong

doi:10.1109/TNS.2012.2210053

A dual-layer TOF-DOI detector block for whole-body PET

Shitao Liu, Shaohui An, Hongdi Li, Chao Wang, Rocio A. Ramirez, Yuxuan Zhang, Hossain Baghaei, Wai Hoi Wong

Cancer Systems Imaging

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We developed a dual-layer high-resolution detector block for whole-body positron-emission tomography systems. The top layer is a 13\times13 array of lutetium yttrium orthosilicate (LYSO) crystals (2.85× 2.85× 10 mm ³) and the bottom layer a 13× 13 array of lutetium gadolinium oxyorthosilicate (LGSO) crystals (2.85× 2.85× 10 mm ³). The LGSO layer was coupled to four Hamamatsu R11194HA photomultiplier tubes (PMTs) by a photomultiplier quadrant-sharing configuration. This block has both time-of-flight and depth-of-interaction functions. Using a Na-22 point source, the performance of this block was evaluated by coinciding with a reference detector which consisted of a 4×4×10 mm ³ LYSO crystal coupled to a Hamamatsu R9779 PMT. A total of 4.7% of the counts were mixed among the two layers. The LYSO layer had 11.4% energy resolution and 329 ps coincidence time resolution against the reference detector. The LGSO layer had 14.8% energy resolution and 356 ps coincidence time resolution against the reference detector.

Original language	English (US)
Article number	6291767
Pages (from-to)	1805-1808
Number of pages	4
Journal	IEEE Transactions on Nuclear Science
Volume	59
Issue number	5 PART 1
DOIs	https://doi.org/10.1109/TNS.2012.2210053
State	Published - 2012

Keywords

Depth of interaction (DOI)
lutetium gadolinium oxyorthosilicate (LGSO)
lutetium yttrium orthosilicate (LYSO)
photomultiplier quadrant sharing (PQS)
positron emission tomography (PET)
time of flight (TOF)

ASJC Scopus subject areas

Nuclear and High Energy Physics
Nuclear Energy and Engineering
Electrical and Electronic Engineering

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10.1109/TNS.2012.2210053

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@article{8399b16cb0c9426d9d605076e6d6a483,

title = "A dual-layer TOF-DOI detector block for whole-body PET",

abstract = "We developed a dual-layer high-resolution detector block for whole-body positron-emission tomography systems. The top layer is a 13\times13 array of lutetium yttrium orthosilicate (LYSO) crystals (2.85× 2.85× 10 mm 3) and the bottom layer a 13× 13 array of lutetium gadolinium oxyorthosilicate (LGSO) crystals (2.85× 2.85× 10 mm 3). The LGSO layer was coupled to four Hamamatsu R11194HA photomultiplier tubes (PMTs) by a photomultiplier quadrant-sharing configuration. This block has both time-of-flight and depth-of-interaction functions. Using a Na-22 point source, the performance of this block was evaluated by coinciding with a reference detector which consisted of a 4×4×10 mm 3 LYSO crystal coupled to a Hamamatsu R9779 PMT. A total of 4.7% of the counts were mixed among the two layers. The LYSO layer had 11.4% energy resolution and 329 ps coincidence time resolution against the reference detector. The LGSO layer had 14.8% energy resolution and 356 ps coincidence time resolution against the reference detector.",

keywords = "Depth of interaction (DOI), lutetium gadolinium oxyorthosilicate (LGSO), lutetium yttrium orthosilicate (LYSO), photomultiplier quadrant sharing (PQS), positron emission tomography (PET), time of flight (TOF)",

author = "Shitao Liu and Shaohui An and Hongdi Li and Chao Wang and Ramirez, {Rocio A.} and Yuxuan Zhang and Hossain Baghaei and Wong, {Wai Hoi}",

note = "Funding Information: Manuscript received July 26, 2011; revised November 21, 2011, March 25, 2012; accepted May 22, 2012. Date of publication August 31, 2012; date of current version October 09, 2012. This work was supported by the National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering under Grant R01-EB001038.",

year = "2012",

doi = "10.1109/TNS.2012.2210053",

language = "English (US)",

volume = "59",

pages = "1805--1808",

journal = "IEEE Transactions on Nuclear Science",

issn = "0018-9499",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

number = "5 PART 1",

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TY - JOUR

T1 - A dual-layer TOF-DOI detector block for whole-body PET

AU - Liu, Shitao

AU - An, Shaohui

AU - Li, Hongdi

AU - Wang, Chao

AU - Ramirez, Rocio A.

AU - Zhang, Yuxuan

AU - Baghaei, Hossain

AU - Wong, Wai Hoi

N1 - Funding Information: Manuscript received July 26, 2011; revised November 21, 2011, March 25, 2012; accepted May 22, 2012. Date of publication August 31, 2012; date of current version October 09, 2012. This work was supported by the National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering under Grant R01-EB001038.

PY - 2012

Y1 - 2012

N2 - We developed a dual-layer high-resolution detector block for whole-body positron-emission tomography systems. The top layer is a 13\times13 array of lutetium yttrium orthosilicate (LYSO) crystals (2.85× 2.85× 10 mm 3) and the bottom layer a 13× 13 array of lutetium gadolinium oxyorthosilicate (LGSO) crystals (2.85× 2.85× 10 mm 3). The LGSO layer was coupled to four Hamamatsu R11194HA photomultiplier tubes (PMTs) by a photomultiplier quadrant-sharing configuration. This block has both time-of-flight and depth-of-interaction functions. Using a Na-22 point source, the performance of this block was evaluated by coinciding with a reference detector which consisted of a 4×4×10 mm 3 LYSO crystal coupled to a Hamamatsu R9779 PMT. A total of 4.7% of the counts were mixed among the two layers. The LYSO layer had 11.4% energy resolution and 329 ps coincidence time resolution against the reference detector. The LGSO layer had 14.8% energy resolution and 356 ps coincidence time resolution against the reference detector.

AB - We developed a dual-layer high-resolution detector block for whole-body positron-emission tomography systems. The top layer is a 13\times13 array of lutetium yttrium orthosilicate (LYSO) crystals (2.85× 2.85× 10 mm 3) and the bottom layer a 13× 13 array of lutetium gadolinium oxyorthosilicate (LGSO) crystals (2.85× 2.85× 10 mm 3). The LGSO layer was coupled to four Hamamatsu R11194HA photomultiplier tubes (PMTs) by a photomultiplier quadrant-sharing configuration. This block has both time-of-flight and depth-of-interaction functions. Using a Na-22 point source, the performance of this block was evaluated by coinciding with a reference detector which consisted of a 4×4×10 mm 3 LYSO crystal coupled to a Hamamatsu R9779 PMT. A total of 4.7% of the counts were mixed among the two layers. The LYSO layer had 11.4% energy resolution and 329 ps coincidence time resolution against the reference detector. The LGSO layer had 14.8% energy resolution and 356 ps coincidence time resolution against the reference detector.

KW - Depth of interaction (DOI)

KW - lutetium gadolinium oxyorthosilicate (LGSO)

KW - lutetium yttrium orthosilicate (LYSO)

KW - photomultiplier quadrant sharing (PQS)

KW - positron emission tomography (PET)

KW - time of flight (TOF)

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U2 - 10.1109/TNS.2012.2210053

DO - 10.1109/TNS.2012.2210053

M3 - Article

AN - SCOPUS:84867580868

SN - 0018-9499

VL - 59

SP - 1805

EP - 1808

JO - IEEE Transactions on Nuclear Science

JF - IEEE Transactions on Nuclear Science

IS - 5 PART 1

M1 - 6291767

ER -

A dual-layer TOF-DOI detector block for whole-body PET

Abstract

Keywords

ASJC Scopus subject areas

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