A facile and selective oxidation of sulfides to sulfones

Waldemar Priebe; Grzegorz Grynkiewicz

doi:10.1016/0040-4039(91)80105-F

A facile and selective oxidation of sulfides to sulfones

Waldemar Priebe, Grzegorz Grynkiewicz

Experimental Therapeutics

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Abstract

Sulfides undergo a facile and selective oxidation to sulfones under mild conditions using a catalytic amount of osmium tetroxide and tertiary amine N-oxides (N-methylmorpholine N-oxide or trimethylamine N-oxide). Both N-oxides are equally effective. The observed yields ranged between 60%-95%.

Original language	English (US)
Pages (from-to)	7353-7356
Number of pages	4
Journal	Tetrahedron Letters
Volume	32
Issue number	50
DOIs	https://doi.org/10.1016/0040-4039(91)80105-F
State	Published - Dec 9 1991

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(91)80105-F

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title = "A facile and selective oxidation of sulfides to sulfones",

abstract = "Sulfides undergo a facile and selective oxidation to sulfones under mild conditions using a catalytic amount of osmium tetroxide and tertiary amine N-oxides (N-methylmorpholine N-oxide or trimethylamine N-oxide). Both N-oxides are equally effective. The observed yields ranged between 60%-95%.",

author = "Waldemar Priebe and Grzegorz Grynkiewicz",

note = "Funding Information: work was suppoitedriln, part, by National Institute$o f Health grant No,",

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T1 - A facile and selective oxidation of sulfides to sulfones

AU - Priebe, Waldemar

AU - Grynkiewicz, Grzegorz

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PY - 1991/12/9

Y1 - 1991/12/9

N2 - Sulfides undergo a facile and selective oxidation to sulfones under mild conditions using a catalytic amount of osmium tetroxide and tertiary amine N-oxides (N-methylmorpholine N-oxide or trimethylamine N-oxide). Both N-oxides are equally effective. The observed yields ranged between 60%-95%.

AB - Sulfides undergo a facile and selective oxidation to sulfones under mild conditions using a catalytic amount of osmium tetroxide and tertiary amine N-oxides (N-methylmorpholine N-oxide or trimethylamine N-oxide). Both N-oxides are equally effective. The observed yields ranged between 60%-95%.

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U2 - 10.1016/0040-4039(91)80105-F

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M3 - Article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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A facile and selective oxidation of sulfides to sulfones

Abstract

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