A fluorescence-coupled assay for gamma aminobutyric acid (GABA) reveals metabolic stress-induced modulation of GABA content in neuroendocrine cancer

Medicine & Life Sciences

• Physiological Stress 99%
• gamma-Aminobutyric Acid 80%
• Fluorescence 68%
• glutamate decarboxylase 1 64%
• Neoplasms 26%
• Cell Line 16%
• Prostate 15%
• resazurin 12%
• Glutamate-Ammonia Ligase 12%
• Neuroendocrine Carcinoma 11%
• Neuroendocrine Cells 11%
• Enzyme Assays 10%
• Atlases 9%
• Glutamine 9%
• Renal Cell Carcinoma 8%
• Disease-Free Survival 8%
• Androgens 8%
• Neurotransmitter Agents 8%
• Prostatic Neoplasms 7%
• Adenocarcinoma 7%
• Acids 7%
• Genome 6%
• Glucose 5%
• Enzymes 5%
• Therapeutics 1%

Agriculture & Biology

• gamma-aminobutyric acid 90%
• neoplasms 63%
• fluorescence 62%
• glutamate decarboxylase 49%
• assays 44%
• cell lines 20%
• neoplasm cells 16%
• synthesis 15%
• renal cell carcinoma 15%
• prostatic neoplasms 12%
• topographic maps 11%
• adenocarcinoma 10%
• glutamate-ammonia ligase 10%
• carcinoma 9%
• androgens 9%
• glutamine 9%
• pathogenesis 8%
• stress response 7%
• therapeutics 7%
• glucose 5%
• metabolism 5%
• organisms 5%
• acids 5%
• genome 5%
• enzymes 4%
• cells 2%

Chemistry

• Gamma-Aminobutyric Acid 100%
• Metabolic 67%
• Glutamine 20%
• Resazurin 14%
• Neurotransmitter 10%
• Pharmacological Metabolism 7%
• Glucose 6%
• Reduction 4%
• Acid 3%