@inproceedings{b9a13e738a744443b47b01ce3f58901d,
title = "A {"}leukolike{"} multistage delivery system to overcome biological barriers",
abstract = "The localization of theranostic nanoparticles (NPs) to a tumor site has been the subject of considerable research that so far has not translated into comparably comforting advances in clinical medicine. Due to limitations in their structure and surface properties, NPs are still unable to overcome the multiplicity of biological barriers they encounter after intravenous administration and that adversely impact their ability to reach the intended target at effective concentrations. We developed a novel hybrid biomimetic delivery system that combines together the characteristics of an artificial multistage delivery system with the physiologic components that trigger the natural ability of leukocytes (T and B cells) to transmigrate from the blood stream to the tumor site.",
keywords = "Biological barriers, Delivery system, Leukocytes, Nanoparticles",
author = "N. Quattrocchi and C. Chiappini and L. Cooper and M. Ferrari and E. Tasciotti",
note = "Copyright: Copyright 2010 Elsevier B.V., All rights reserved.; Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy - 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010 ; Conference date: 21-06-2010 Through 24-06-2010",
year = "2010",
language = "English (US)",
isbn = "9781439834152",
series = "Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010",
pages = "346--349",
booktitle = "Nanotechnology 2010",
}