A method for immunoisolation of sporocysts of Schistosoma mansoni in nonsusceptible snails

J. T. Sullivan, P. C. Hu

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A technique is described for immunoisolation of sporocysts of Schistosoma mansoni in nonsusceptible Biomphalaria glabrata by microencapsulation in agarose. Based on histological evidence, all 11 microencapsulated sporocysts implanted into 3 schistosome-resistant 13-16-R1 snails were alive at 72 hr postimplantation, although in a developmentally retarded condition. However, among 146 sporocysts derived from miracidia that had penetrated 5 snails, 96% were dead by 72 hr. These results suggest that hemocyte contact is necessary for rapid sporocyst death in vivo.

Original languageEnglish (US)
Pages (from-to)1029-1031
Number of pages3
JournalJournal of Parasitology
Volume81
Issue number6
DOIs
StatePublished - 1995
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Ecology, Evolution, Behavior and Systematics

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