A Novel Role for a Familiar Protein in Apoptosis Induced by Proteasome Inhibition

David J. McConkey

doi:10.1016/j.ccr.2008.06.011

A Novel Role for a Familiar Protein in Apoptosis Induced by Proteasome Inhibition

David J. McConkey

Urology

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

In this issue of Cancer Cell, Nickeleit et al. (2008) identify a new proteasome inhibitor, argyrin A, and show that it induces apoptosis and inhibits angiogenesis via p27-dependent mechanisms. Their observations challenge current thinking about how this class of promising cancer therapies works and why they selectively kill cancer cells.

Original language	English (US)
Pages (from-to)	1-2
Number of pages	2
Journal	Cancer cell
Volume	14
Issue number	1
DOIs	https://doi.org/10.1016/j.ccr.2008.06.011
State	Published - Jul 8 2008

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2008.06.011

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title = "A Novel Role for a Familiar Protein in Apoptosis Induced by Proteasome Inhibition",

abstract = "In this issue of Cancer Cell, Nickeleit et al. (2008) identify a new proteasome inhibitor, argyrin A, and show that it induces apoptosis and inhibits angiogenesis via p27-dependent mechanisms. Their observations challenge current thinking about how this class of promising cancer therapies works and why they selectively kill cancer cells.",

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AB - In this issue of Cancer Cell, Nickeleit et al. (2008) identify a new proteasome inhibitor, argyrin A, and show that it induces apoptosis and inhibits angiogenesis via p27-dependent mechanisms. Their observations challenge current thinking about how this class of promising cancer therapies works and why they selectively kill cancer cells.

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A Novel Role for a Familiar Protein in Apoptosis Induced by Proteasome Inhibition

Abstract

ASJC Scopus subject areas

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