TY - JOUR
T1 - A proposed staging system for chronic myeloid leukemia
AU - Ross, Dennis W.
AU - Brunning, Richard D.
AU - Kantarjian, Hagop M.
AU - Phillip Koeffler, H.
AU - Ozer, Howard
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1993/6/1
Y1 - 1993/6/1
N2 - A staging system was proposed for chronic myeloid leukemia (CML) that groups patients into three stages (I, II, and III), each with two subclasses (A and B). The system uses pathologic parameters, of which the percentage of blasts in the blood and bone marrow is the most important. CML is defined as a myeloproliferative disorder with molecular or cytogenetic evidence of the translocation of the abl oncogene on chromosome 9 to the breakpoint cluster region gene on chromosome 22. The proposed staging system is similar in format to the standard TNM system used for many solid tumors.
AB - A staging system was proposed for chronic myeloid leukemia (CML) that groups patients into three stages (I, II, and III), each with two subclasses (A and B). The system uses pathologic parameters, of which the percentage of blasts in the blood and bone marrow is the most important. CML is defined as a myeloproliferative disorder with molecular or cytogenetic evidence of the translocation of the abl oncogene on chromosome 9 to the breakpoint cluster region gene on chromosome 22. The proposed staging system is similar in format to the standard TNM system used for many solid tumors.
KW - blasts
KW - chronic myeloid leukemia
KW - classification
KW - staging
UR - http://www.scopus.com/inward/record.url?scp=0027319651&partnerID=8YFLogxK
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U2 - 10.1002/1097-0142(19930601)71:11<3788::AID-CNCR2820711150>3.0.CO;2-7
DO - 10.1002/1097-0142(19930601)71:11<3788::AID-CNCR2820711150>3.0.CO;2-7
M3 - Letter
C2 - 8490930
AN - SCOPUS:0027319651
SN - 0008-543X
VL - 71
SP - 3788
EP - 3791
JO - Cancer
JF - Cancer
IS - 11
ER -