A prospective pilot study comparing rate of processing techniques in autologous fat grafting

Research output: Contribution to journalArticle

Abstract

Background Autologous fat grafting (AFG) is increasing in popularity to address a variety of defects. There is interest in developing techniques to harvest, process, and inject fat to improve clinical outcomes as well as operative efficiency. Objectives The purpose of this pilot study is to compare the rate of graft processing of two commercially available systems for graft preparation. Methods Twenty consecutive cases using an active filtration system (system-AF) were observed followed by 20 consecutive cases using a passive filtration system (system-PF) to compare efficiency rate. Fat processing rate was quantified in milliliters/minute. Results Forty patients underwent AFG with no differences in patient characteristics between the groups. There was 1 incidence of palpable fat necrosis per group (5%). For all patients, this was the first fat grafting procedure; 20% of patients (n = 4 per group) had additional fat grafting. Overall, the rate of adipose tissue preparation was significantly higher with system-AF compared to system-PF (19.8 mL/min vs 5.3 mL/min, P ≤ 0.001). The resulting percent of graftable fat was comparable (AF: 41% vs PF: 42%; P = 0.83). Conclusions Time and motion studies such as this provide a means to systematically document each of the steps involved in fat grafting in a reliable fashion. The authors demonstrate a significantly higher rate of lipoaspirate processing using an active filtration system compared to a passive system. Further large-scale studies of the efficacy and cost analysis of AFG are a necessary component of determining best practices in the field. Level of Evidence: 2

Original languageEnglish (US)
Pages (from-to)331-337
Number of pages7
JournalAesthetic surgery journal
Volume39
Issue number3
DOIs
StatePublished - Feb 15 2019

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Fats
Prospective Studies
Fat Necrosis
Transplants
Efficiency
Time and Motion Studies
Practice Guidelines
Adipose Tissue
Costs and Cost Analysis
Incidence

ASJC Scopus subject areas

  • Surgery

Cite this

@article{f122d7fa112143f5bebed7577fd7f975,
title = "A prospective pilot study comparing rate of processing techniques in autologous fat grafting",
abstract = "Background Autologous fat grafting (AFG) is increasing in popularity to address a variety of defects. There is interest in developing techniques to harvest, process, and inject fat to improve clinical outcomes as well as operative efficiency. Objectives The purpose of this pilot study is to compare the rate of graft processing of two commercially available systems for graft preparation. Methods Twenty consecutive cases using an active filtration system (system-AF) were observed followed by 20 consecutive cases using a passive filtration system (system-PF) to compare efficiency rate. Fat processing rate was quantified in milliliters/minute. Results Forty patients underwent AFG with no differences in patient characteristics between the groups. There was 1 incidence of palpable fat necrosis per group (5{\%}). For all patients, this was the first fat grafting procedure; 20{\%} of patients (n = 4 per group) had additional fat grafting. Overall, the rate of adipose tissue preparation was significantly higher with system-AF compared to system-PF (19.8 mL/min vs 5.3 mL/min, P ≤ 0.001). The resulting percent of graftable fat was comparable (AF: 41{\%} vs PF: 42{\%}; P = 0.83). Conclusions Time and motion studies such as this provide a means to systematically document each of the steps involved in fat grafting in a reliable fashion. The authors demonstrate a significantly higher rate of lipoaspirate processing using an active filtration system compared to a passive system. Further large-scale studies of the efficacy and cost analysis of AFG are a necessary component of determining best practices in the field. Level of Evidence: 2",
author = "Hanson, {Summer Elizabeth} and Garvey, {Patrick Bryan} and Chang, {Edward I-Fei} and Reece, {Greg P} and Jun Liu and Butler, {Charles E}",
year = "2019",
month = "2",
day = "15",
doi = "10.1093/asj/sjy154",
language = "English (US)",
volume = "39",
pages = "331--337",
journal = "Aesthetic Surgery Journal",
issn = "1090-820X",
publisher = "SAGE Publications Inc.",
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T1 - A prospective pilot study comparing rate of processing techniques in autologous fat grafting

AU - Hanson, Summer Elizabeth

AU - Garvey, Patrick Bryan

AU - Chang, Edward I-Fei

AU - Reece, Greg P

AU - Liu, Jun

AU - Butler, Charles E

PY - 2019/2/15

Y1 - 2019/2/15

N2 - Background Autologous fat grafting (AFG) is increasing in popularity to address a variety of defects. There is interest in developing techniques to harvest, process, and inject fat to improve clinical outcomes as well as operative efficiency. Objectives The purpose of this pilot study is to compare the rate of graft processing of two commercially available systems for graft preparation. Methods Twenty consecutive cases using an active filtration system (system-AF) were observed followed by 20 consecutive cases using a passive filtration system (system-PF) to compare efficiency rate. Fat processing rate was quantified in milliliters/minute. Results Forty patients underwent AFG with no differences in patient characteristics between the groups. There was 1 incidence of palpable fat necrosis per group (5%). For all patients, this was the first fat grafting procedure; 20% of patients (n = 4 per group) had additional fat grafting. Overall, the rate of adipose tissue preparation was significantly higher with system-AF compared to system-PF (19.8 mL/min vs 5.3 mL/min, P ≤ 0.001). The resulting percent of graftable fat was comparable (AF: 41% vs PF: 42%; P = 0.83). Conclusions Time and motion studies such as this provide a means to systematically document each of the steps involved in fat grafting in a reliable fashion. The authors demonstrate a significantly higher rate of lipoaspirate processing using an active filtration system compared to a passive system. Further large-scale studies of the efficacy and cost analysis of AFG are a necessary component of determining best practices in the field. Level of Evidence: 2

AB - Background Autologous fat grafting (AFG) is increasing in popularity to address a variety of defects. There is interest in developing techniques to harvest, process, and inject fat to improve clinical outcomes as well as operative efficiency. Objectives The purpose of this pilot study is to compare the rate of graft processing of two commercially available systems for graft preparation. Methods Twenty consecutive cases using an active filtration system (system-AF) were observed followed by 20 consecutive cases using a passive filtration system (system-PF) to compare efficiency rate. Fat processing rate was quantified in milliliters/minute. Results Forty patients underwent AFG with no differences in patient characteristics between the groups. There was 1 incidence of palpable fat necrosis per group (5%). For all patients, this was the first fat grafting procedure; 20% of patients (n = 4 per group) had additional fat grafting. Overall, the rate of adipose tissue preparation was significantly higher with system-AF compared to system-PF (19.8 mL/min vs 5.3 mL/min, P ≤ 0.001). The resulting percent of graftable fat was comparable (AF: 41% vs PF: 42%; P = 0.83). Conclusions Time and motion studies such as this provide a means to systematically document each of the steps involved in fat grafting in a reliable fashion. The authors demonstrate a significantly higher rate of lipoaspirate processing using an active filtration system compared to a passive system. Further large-scale studies of the efficacy and cost analysis of AFG are a necessary component of determining best practices in the field. Level of Evidence: 2

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