Abstract
A 57-year-old woman admitted for right hypochondoralgia had normal laboratory data and tumor markers and was negative for hepatitis virus type B s-antigen and type C antibody. Ultrasonography showed extremely hypoechoic hepatic tumors of 8.3 × 6.5cm in diameter at segment 6 and 1.7 × 1.5cm at segmen 8. Drip-infusion cholangiography computed tomography showed highly dense straight vasculature in the S8 tumor, considered to be the biliary duct. Needle biopsy specimens showed undifferentiated carcinoma, necessitating extended right hepatectomy. We found no abdominal splenomegaly or lymphadenopathy, and tumors appeared localized in the liver. Microscopic findings of resected specimens showed tumors to be composed of round lymphocyte-like cells. CD20 protein was positive immunohistochemically, leading to a diagnosis of primary non-Hodgkin's hepatic lymphoma type B. To ensure definitive diagnosis, we should first consider primary lymphoma differentially, then conduct immunohistochemical staining with biopsy specimens.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 644-649 |
| Number of pages | 6 |
| Journal | Japanese Journal of Gastroenterological Surgery |
| Volume | 38 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2005 |
Keywords
- Immunohistochemical staining
- Needle biopsy
- Primary hepatic lymphoma
ASJC Scopus subject areas
- Surgery
- Gastroenterology