A review of stereotactic radiosurgery practice in the management of skull base meningiomas

Elena Vera; J. Bryan Iorgulescu; Daniel M.S. Raper; Karthik Madhavan; Brian E. Lally; Jacques Morcos; Samy Elhammady; Jonathan Sherman; Ricardo J. Komotar

doi:10.1055/s-0033-1354747

A review of stereotactic radiosurgery practice in the management of skull base meningiomas

Elena Vera, J. Bryan Iorgulescu, Daniel M.S. Raper, Karthik Madhavan, Brian E. Lally, Jacques Morcos, Samy Elhammady, Jonathan Sherman, Ricardo J. Komotar

Research output: Contribution to journal › Review article › peer-review

20 Scopus citations

Abstract

Gross total resection of skull base meningiomas poses a surgical challenge due to their proximity to neurovascular structures. Once the gold standard therapy for skull base meningiomas, microsurgery has been gradually replaced by or used in combination with stereotactic radiosurgery (SRS). This review surveys the safety and efficacy of SRS in the treatment of cranial base meningiomas including 36 articles from 1991 to 2010. SRS produces excellent tumor control with low morbidity rates compared with surgery alone for asymptomatic small skull base meningiomas, patients with risk factors precluding conventional surgery, and as adjuvant therapy for recurrent or residual lesions.

Original language	English (US)
Pages (from-to)	152-158
Number of pages	7
Journal	Journal of Neurological Surgery, Part B: Skull Base
Volume	75
Issue number	3
DOIs	https://doi.org/10.1055/s-0033-1354747
State	Published - Jun 2014
Externally published	Yes

Keywords

meningiomas
radiosurgery
skull base
stereotactic
surgery

ASJC Scopus subject areas

Clinical Neurology

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10.1055/s-0033-1354747

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abstract = "Gross total resection of skull base meningiomas poses a surgical challenge due to their proximity to neurovascular structures. Once the gold standard therapy for skull base meningiomas, microsurgery has been gradually replaced by or used in combination with stereotactic radiosurgery (SRS). This review surveys the safety and efficacy of SRS in the treatment of cranial base meningiomas including 36 articles from 1991 to 2010. SRS produces excellent tumor control with low morbidity rates compared with surgery alone for asymptomatic small skull base meningiomas, patients with risk factors precluding conventional surgery, and as adjuvant therapy for recurrent or residual lesions.",

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AU - Iorgulescu, J. Bryan

AU - Raper, Daniel M.S.

AU - Madhavan, Karthik

AU - Lally, Brian E.

AU - Morcos, Jacques

AU - Elhammady, Samy

AU - Sherman, Jonathan

AU - Komotar, Ricardo J.

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AB - Gross total resection of skull base meningiomas poses a surgical challenge due to their proximity to neurovascular structures. Once the gold standard therapy for skull base meningiomas, microsurgery has been gradually replaced by or used in combination with stereotactic radiosurgery (SRS). This review surveys the safety and efficacy of SRS in the treatment of cranial base meningiomas including 36 articles from 1991 to 2010. SRS produces excellent tumor control with low morbidity rates compared with surgery alone for asymptomatic small skull base meningiomas, patients with risk factors precluding conventional surgery, and as adjuvant therapy for recurrent or residual lesions.

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A review of stereotactic radiosurgery practice in the management of skull base meningiomas

Abstract

Keywords

ASJC Scopus subject areas

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