A swiss army knife for CTLs

Peter Friedl; Bettina Weigelin

doi:10.1016/j.immuni.2014.12.008

A swiss army knife for CTLs

Peter Friedl, Bettina Weigelin

Genitourinary Medical Oncology

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell lysis. In this issue of Immunity, Prakash etal. (2014) demonstrate that granzyme B cleaves basement membrane proteins and promotes cytotoxic Tcell diapedesis into inflamed tissue. Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell lysis. Prakash etal. demonstrate that granzyme B cleaves basement membrane proteins and promotes cytotoxic Tcell diapedesis into inflamed tissue.

Original language	English (US)
Pages (from-to)	873-875
Number of pages	3
Journal	Immunity
Volume	41
Issue number	6
DOIs	https://doi.org/10.1016/j.immuni.2014.12.008
State	Published - Dec 18 2014

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2014.12.008

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title = "A swiss army knife for CTLs",

abstract = "Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell lysis. In this issue of Immunity, Prakash etal. (2014) demonstrate that granzyme B cleaves basement membrane proteins and promotes cytotoxic Tcell diapedesis into inflamed tissue. Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell lysis. Prakash etal. demonstrate that granzyme B cleaves basement membrane proteins and promotes cytotoxic Tcell diapedesis into inflamed tissue.",

author = "Peter Friedl and Bettina Weigelin",

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year = "2014",

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AU - Weigelin, Bettina

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AB - Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell lysis. In this issue of Immunity, Prakash etal. (2014) demonstrate that granzyme B cleaves basement membrane proteins and promotes cytotoxic Tcell diapedesis into inflamed tissue. Granzyme B released by leukocytes cleaves multiple intracellular substrates required for target cell lysis. Prakash etal. demonstrate that granzyme B cleaves basement membrane proteins and promotes cytotoxic Tcell diapedesis into inflamed tissue.

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A swiss army knife for CTLs

Abstract

ASJC Scopus subject areas

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