Abdominal aorta: Evaluation with dual-source dual-energy multidetector CT after endovascular repair of aneurysms-initial observations

Hersh Chandarana, Myrna C.B. Godoy, Loannis Vlahos, Anno Graser, James Babb, Christianne Leidecker, Michael Macari

Research output: Contribution to journalArticlepeer-review

148 Scopus citations

Abstract

Purpose: To evaluate the possible radiation dose reduction facilitated by using dual-energy (DE) multidetector computed tomography (CT) after endovascular repair of abdominal aortic aneurysms (AAAs). Materials and Methods: This prospective study was HIPAA compliant and institutional review board approved. Twenty-two patients who previously had undergone endovascular repair of AAAs underwent 24 DE multidetector CT examinations, which were performed with a 64-detector scanner. Initial nonen- hanced CT was followed by arterial phase and venous phase acquisitions. Virtual nonenhanced, pure 80-kVp, and weighted-average peak voltage CT data sets were generated from the venous acquisition. Two independent readers interpreted the virtual nonenhanced and DE weighted-average CT data for the presence or absence of endoleaks. These interpretations were compared with the clinical interpretations of the data performed by a different radiologist by using true nonenhanced, arterial phase, and venous phase data. Region-of-interest measurements of the abdominal aorta and of the region of the endoleaks were obtained. Effective radiation dose was calculated. Results: Both independent readers' interpretations of the virtual nonenhanced and weighted-average venous CT data revealed six type II endoleaks. There were no false-positive or false-negative findings. Aortic attenuation during the arterial, 80-kVp venous, and weighted-average data acquisitions were 288, 213, and 150 HU, respectively. The attenuation ofthe endoleaks was higher during the 80-kVp acquisition (P < .03) than during the arterial phase and weighted-average venous phase acquisitions. The mean effective dose for DE venous phase CT was 11.1 mSv compared with 27.8 mSv for standard triple-phase CT with a single-source configuration. Conclusion: Preliminary observations suggest that obtaining DE multi- detector CT data by using a single 60-second contrast material- enhanced acquisition may be all that is required for surveillance after endovascular repair of AAA.

Original languageEnglish (US)
Pages (from-to)692-700
Number of pages9
JournalRadiology
Volume249
Issue number2
DOIs
StatePublished - Nov 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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