Achieving Fidelity in Homologous Recombination Despite Extreme Complexity: Informed Decisions by Molecular Profiling

Robert P. Rambo; Gareth J. Williams; John A. Tainer

doi:10.1016/j.molcel.2010.10.032

Achieving Fidelity in Homologous Recombination Despite Extreme Complexity: Informed Decisions by Molecular Profiling

Robert P. Rambo, Gareth J. Williams, John A. Tainer

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

In this issue of Molecular Cell, Savir and Tlusty (2010) apply signal detection theory to show that homologous recombination machinery is optimally tuned to find homologous DNA sequences within an exceptionally high background of heterologous sequences.

Original language	English (US)
Pages (from-to)	347-348
Number of pages	2
Journal	Molecular cell
Volume	40
Issue number	3
DOIs	https://doi.org/10.1016/j.molcel.2010.10.032
State	Published - Nov 12 2010
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2010.10.032

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title = "Achieving Fidelity in Homologous Recombination Despite Extreme Complexity: Informed Decisions by Molecular Profiling",

abstract = "In this issue of Molecular Cell, Savir and Tlusty (2010) apply signal detection theory to show that homologous recombination machinery is optimally tuned to find homologous DNA sequences within an exceptionally high background of heterologous sequences.",

author = "Rambo, {Robert P.} and Williams, {Gareth J.} and Tainer, {John A.}",

year = "2010",

month = nov,

day = "12",

doi = "10.1016/j.molcel.2010.10.032",

language = "English (US)",

volume = "40",

pages = "347--348",

journal = "Molecular cell",

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publisher = "Cell Press",

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T1 - Achieving Fidelity in Homologous Recombination Despite Extreme Complexity

T2 - Informed Decisions by Molecular Profiling

AU - Rambo, Robert P.

AU - Williams, Gareth J.

AU - Tainer, John A.

PY - 2010/11/12

Y1 - 2010/11/12

N2 - In this issue of Molecular Cell, Savir and Tlusty (2010) apply signal detection theory to show that homologous recombination machinery is optimally tuned to find homologous DNA sequences within an exceptionally high background of heterologous sequences.

AB - In this issue of Molecular Cell, Savir and Tlusty (2010) apply signal detection theory to show that homologous recombination machinery is optimally tuned to find homologous DNA sequences within an exceptionally high background of heterologous sequences.

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UR - http://www.scopus.com/inward/citedby.url?scp=78149422766&partnerID=8YFLogxK

U2 - 10.1016/j.molcel.2010.10.032

DO - 10.1016/j.molcel.2010.10.032

M3 - Short survey

C2 - 21070960

AN - SCOPUS:78149422766

SN - 1097-2765

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SP - 347

EP - 348

JO - Molecular cell

JF - Molecular cell

IS - 3

ER -

Achieving Fidelity in Homologous Recombination Despite Extreme Complexity: Informed Decisions by Molecular Profiling

Abstract

ASJC Scopus subject areas

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