Acquired resistance to selective estrogen receptor modulators (SERMs) in clinical practice (tamoxifen & raloxifene) by selection pressure in breast cancer cell populations

Medicine & Life Sciences

• Raloxifene Hydrochloride 82%
• Selective Estrogen Receptor Modulators 80%
• Tamoxifen 64%
• Pressure 39%
• Breast Neoplasms 38%
• Population 23%
• Estrogens 15%
• Growth 9%
• Estrogen Receptors 8%
• Therapeutics 6%
• Neoplasms 6%
• Survival 5%
• Nude Mice 4%
• Drug Resistance 4%
• Clinical Trials 3%
• Apoptosis 2%
• Membranes 2%
• Genes 1%

Chemistry

• Raloxifene 100%
• Tamoxifen 82%
• Estrogen 41%
• Resistance 38%
• Pressure 34%
• Adjuvant 13%
• Plastic Property 6%
• Agonist 5%
• Error 4%
• Length 3%
• Environment 3%
• Molecule 1%
• Application 1%