Actinic granuloma occurring in an unusual association with cutaneous B-cell chronic lymphocytic leukemia

Julia A. Kauffman; Doina Ivan; Jonathan E. Cutlan; Sharon R. Hymes

doi:10.1111/j.1600-0560.2011.01811.x

Actinic granuloma occurring in an unusual association with cutaneous B-cell chronic lymphocytic leukemia

Julia A. Kauffman, Doina Ivan, Jonathan E. Cutlan, Sharon R. Hymes

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Granulomatous cutaneous reactions are well described in association with T-cell non-Hodgkin lymphoma and Hodgkin lymphoma, but are rarely seen in association with B-cell non-Hodgkin lymphoma or leukemia. We report a case of a 65-year-old woman with B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who presented with multiple, tender, firm pink papules on the face, upper trunk and upper extremities 6 years after diagnosis of CLL. Biopsy revealed both palisading granulomatous dermatitis consistent with actinic granuloma and a dense perivascular lymphocytic infiltrate consistent with the patient's known history of leukemia. This is an unusual manifestation of cutaneous B-cell CLL that is rarely seen.

Original language	English (US)
Pages (from-to)	294-297
Number of pages	4
Journal	Journal of cutaneous pathology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1111/j.1600-0560.2011.01811.x
State	Published - Feb 2012

Keywords

Collagenolytic granulomas
Cutaneous lymphoma
Granuloma
Skin

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Dermatology

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10.1111/j.1600-0560.2011.01811.x

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abstract = "Granulomatous cutaneous reactions are well described in association with T-cell non-Hodgkin lymphoma and Hodgkin lymphoma, but are rarely seen in association with B-cell non-Hodgkin lymphoma or leukemia. We report a case of a 65-year-old woman with B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who presented with multiple, tender, firm pink papules on the face, upper trunk and upper extremities 6 years after diagnosis of CLL. Biopsy revealed both palisading granulomatous dermatitis consistent with actinic granuloma and a dense perivascular lymphocytic infiltrate consistent with the patient's known history of leukemia. This is an unusual manifestation of cutaneous B-cell CLL that is rarely seen.",

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Actinic granuloma occurring in an unusual association with cutaneous B-cell chronic lymphocytic leukemia

Abstract

Keywords

ASJC Scopus subject areas

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