Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant staphylococcus aureus

V. Chokkavelu; P. Chandrasekar; K. Rolston; J. L. LeFrock; R. F. Schell

doi:10.1159/000238254

Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant staphylococcus aureus

V. Chokkavelu, P. Chandrasekar, K. Rolston, J. L. LeFrock, R. F. Schell

Infectious Diseases, Infection Control, and Employee Health

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant Staphylococcus aureus was studied using a microtiter broth dilution technique. Coumermycin was the most active agent. Vancomycin, rifampin, fusidic acid and N-formimidoyl-thienamycin showed excellent activity aginst methicillin-resistant St. aureus (MRSA). Antimicrobial susceptibility pattern was similar for MRSA and methicillin- and rifampin-resistant St. aureus. 8% of MRSA were resistant to trimethoprim and sulfamethoxazole.

Original language	English (US)
Pages (from-to)	97-101
Number of pages	5
Journal	Chemotherapy
Volume	30
Issue number	2
DOIs	https://doi.org/10.1159/000238254
State	Published - 1984

Keywords

Coumermycin
Fusidic acid
Methicillin-resistant staphylococcus aureus
Trimethoprim/sulfamethoxazole
Vancomycin

ASJC Scopus subject areas

Oncology
Pharmacology
Drug Discovery
Pharmacology (medical)
Infectious Diseases

Access to Document

10.1159/000238254

Cite this

@article{99fd769795e1431e9150cc68c57ff0af,

title = "Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant staphylococcus aureus",

abstract = "Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant Staphylococcus aureus was studied using a microtiter broth dilution technique. Coumermycin was the most active agent. Vancomycin, rifampin, fusidic acid and N-formimidoyl-thienamycin showed excellent activity aginst methicillin-resistant St. aureus (MRSA). Antimicrobial susceptibility pattern was similar for MRSA and methicillin- and rifampin-resistant St. aureus. 8% of MRSA were resistant to trimethoprim and sulfamethoxazole.",

keywords = "Coumermycin, Fusidic acid, Methicillin-resistant staphylococcus aureus, Trimethoprim/sulfamethoxazole, Vancomycin",

author = "V. Chokkavelu and P. Chandrasekar and K. Rolston and LeFrock, {J. L.} and Schell, {R. F.}",

year = "1984",

doi = "10.1159/000238254",

language = "English (US)",

volume = "30",

pages = "97--101",

journal = "Chemotherapy",

issn = "0009-3157",

publisher = "S. Karger AG",

number = "2",

}

TY - JOUR

T1 - Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant staphylococcus aureus

AU - Chokkavelu, V.

AU - Chandrasekar, P.

AU - Rolston, K.

AU - LeFrock, J. L.

AU - Schell, R. F.

PY - 1984

Y1 - 1984

N2 - Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant Staphylococcus aureus was studied using a microtiter broth dilution technique. Coumermycin was the most active agent. Vancomycin, rifampin, fusidic acid and N-formimidoyl-thienamycin showed excellent activity aginst methicillin-resistant St. aureus (MRSA). Antimicrobial susceptibility pattern was similar for MRSA and methicillin- and rifampin-resistant St. aureus. 8% of MRSA were resistant to trimethoprim and sulfamethoxazole.

AB - Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant Staphylococcus aureus was studied using a microtiter broth dilution technique. Coumermycin was the most active agent. Vancomycin, rifampin, fusidic acid and N-formimidoyl-thienamycin showed excellent activity aginst methicillin-resistant St. aureus (MRSA). Antimicrobial susceptibility pattern was similar for MRSA and methicillin- and rifampin-resistant St. aureus. 8% of MRSA were resistant to trimethoprim and sulfamethoxazole.

KW - Coumermycin

KW - Fusidic acid

KW - Methicillin-resistant staphylococcus aureus

KW - Trimethoprim/sulfamethoxazole

KW - Vancomycin

UR - http://www.scopus.com/inward/record.url?scp=0021288711&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021288711&partnerID=8YFLogxK

U2 - 10.1159/000238254

DO - 10.1159/000238254

M3 - Article

C2 - 6559665

AN - SCOPUS:0021288711

SN - 0009-3157

VL - 30

SP - 97

EP - 101

JO - Chemotherapy

JF - Chemotherapy

IS - 2

ER -

Activity of eleven antimicrobial agents against methicillin-, methicillin-and rifampin-resistant staphylococcus aureus

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this