Acute confusional states in patients with advanced cancer

Friedrich Stiefel; Robin Fainsinger; Eduardo Bruera

doi:10.1016/0885-3924(92)90120-7

Acute confusional states in patients with advanced cancer

Friedrich Stiefel, Robin Fainsinger, Eduardo Bruera

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

In 39 of 100 cancer patients admitted to the palliative care unit at Edmonton General Hospital, the presence of delirium during their last week of life required psychotropic drug treatment. In 10 of the 39 delirious patients, symptoms were only controllable by sedation; this was achieved in 9 patients by a continuous subcutaneous infusion of midazolam. Although haloperidol is considered to be the treatment of choice in agitated, delirious cancer patients, our data suggest that palliative care treatment strategies for these patients may be different.

Original language	English (US)
Pages (from-to)	94-98
Number of pages	5
Journal	Journal of pain and symptom management
Volume	7
Issue number	2
DOIs	https://doi.org/10.1016/0885-3924(92)90120-7
State	Published - Feb 1992
Externally published	Yes

Keywords

Delirium
cancer
midazolam
psychotropic drug

ASJC Scopus subject areas

General Nursing
Clinical Neurology
Anesthesiology and Pain Medicine

Access to Document

10.1016/0885-3924(92)90120-7

Cite this

@article{65abb5312a714c0697b9c26ebf21e8c2,

title = "Acute confusional states in patients with advanced cancer",

abstract = "In 39 of 100 cancer patients admitted to the palliative care unit at Edmonton General Hospital, the presence of delirium during their last week of life required psychotropic drug treatment. In 10 of the 39 delirious patients, symptoms were only controllable by sedation; this was achieved in 9 patients by a continuous subcutaneous infusion of midazolam. Although haloperidol is considered to be the treatment of choice in agitated, delirious cancer patients, our data suggest that palliative care treatment strategies for these patients may be different.",

keywords = "Delirium, cancer, midazolam, psychotropic drug",

author = "Friedrich Stiefel and Robin Fainsinger and Eduardo Bruera",

year = "1992",

month = feb,

doi = "10.1016/0885-3924(92)90120-7",

language = "English (US)",

volume = "7",

pages = "94--98",

journal = "Journal of pain and symptom management",

issn = "0885-3924",

publisher = "Elsevier Inc.",

number = "2",

}

TY - JOUR

T1 - Acute confusional states in patients with advanced cancer

AU - Stiefel, Friedrich

AU - Fainsinger, Robin

AU - Bruera, Eduardo

PY - 1992/2

Y1 - 1992/2

N2 - In 39 of 100 cancer patients admitted to the palliative care unit at Edmonton General Hospital, the presence of delirium during their last week of life required psychotropic drug treatment. In 10 of the 39 delirious patients, symptoms were only controllable by sedation; this was achieved in 9 patients by a continuous subcutaneous infusion of midazolam. Although haloperidol is considered to be the treatment of choice in agitated, delirious cancer patients, our data suggest that palliative care treatment strategies for these patients may be different.

AB - In 39 of 100 cancer patients admitted to the palliative care unit at Edmonton General Hospital, the presence of delirium during their last week of life required psychotropic drug treatment. In 10 of the 39 delirious patients, symptoms were only controllable by sedation; this was achieved in 9 patients by a continuous subcutaneous infusion of midazolam. Although haloperidol is considered to be the treatment of choice in agitated, delirious cancer patients, our data suggest that palliative care treatment strategies for these patients may be different.

KW - Delirium

KW - cancer

KW - midazolam

KW - psychotropic drug

UR - http://www.scopus.com/inward/record.url?scp=0026576759&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026576759&partnerID=8YFLogxK

U2 - 10.1016/0885-3924(92)90120-7

DO - 10.1016/0885-3924(92)90120-7

M3 - Article

C2 - 1573291

AN - SCOPUS:0026576759

SN - 0885-3924

VL - 7

SP - 94

EP - 98

JO - Journal of pain and symptom management

JF - Journal of pain and symptom management

IS - 2

ER -

Acute confusional states in patients with advanced cancer

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this