ACVR1 mutations and the genomic landscape of pediatric diffuse glioma

Gelareh Zadeh; Kenneth Aldape

doi:10.1038/ng.2970

ACVR1 mutations and the genomic landscape of pediatric diffuse glioma

Gelareh Zadeh, Kenneth Aldape

Pathology

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

Pediatric diffuse gliomas are rare but aggressive brain tumors for which effective therapies are unavailable. New studies identify recurrent mutations of the ACVR1 gene in these tumors, identify molecular subtypes and highlight differences between gliomas affecting children and adults.

Original language	English (US)
Pages (from-to)	421-422
Number of pages	2
Journal	Nature Genetics
Volume	46
Issue number	5
DOIs	https://doi.org/10.1038/ng.2970
State	Published - May 2014

ASJC Scopus subject areas

Genetics

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10.1038/ng.2970

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title = "ACVR1 mutations and the genomic landscape of pediatric diffuse glioma",

abstract = "Pediatric diffuse gliomas are rare but aggressive brain tumors for which effective therapies are unavailable. New studies identify recurrent mutations of the ACVR1 gene in these tumors, identify molecular subtypes and highlight differences between gliomas affecting children and adults.",

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ACVR1 mutations and the genomic landscape of pediatric diffuse glioma

Abstract

ASJC Scopus subject areas

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