TY - JOUR
T1 - Adjuvant and neoadjuvant therapy for gastric cancer
AU - Gonzalez, Ricardo J.
AU - Mansfield, Paul F.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/10
Y1 - 2005/10
N2 - The incidence of gastric cancer in the United States is decreasing; however, this disease still results in considerable mortality. Although effective surgical resection abiding by accepted oncologic principles allows for the highest probability of a cure, additional therapy in the form of neoadjuvant or adjuvant techniques may improve survival and quality of life. Well-designed prospective randomized trials are needed to determine whether the addition of new antineoplastic agents, the use of inhibitors of angiogenesis, or preoperative as opposed to postoperative therapy will further improve survival rates for this disease.
AB - The incidence of gastric cancer in the United States is decreasing; however, this disease still results in considerable mortality. Although effective surgical resection abiding by accepted oncologic principles allows for the highest probability of a cure, additional therapy in the form of neoadjuvant or adjuvant techniques may improve survival and quality of life. Well-designed prospective randomized trials are needed to determine whether the addition of new antineoplastic agents, the use of inhibitors of angiogenesis, or preoperative as opposed to postoperative therapy will further improve survival rates for this disease.
UR - http://www.scopus.com/inward/record.url?scp=24044520336&partnerID=8YFLogxK
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U2 - 10.1016/j.suc.2005.05.004
DO - 10.1016/j.suc.2005.05.004
M3 - Review article
C2 - 16139035
AN - SCOPUS:24044520336
SN - 0039-6109
VL - 85
SP - 1033
EP - 1051
JO - Surgical Clinics of North America
JF - Surgical Clinics of North America
IS - 5
ER -